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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei140GTPUniRule annotation1
Binding sitei144GTPUniRule annotation1
Binding sitei188GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 26GTPUniRule annotation5
Nucleotide bindingi109 – 111GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:LIC_12969Imported
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)Imported
Taxonomic identifieri267671 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000007037 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ72N68

Interactioni

Protein-protein interaction databases

STRINGi267671.LIC12969

Structurei

3D structure databases

ProteinModelPortaliQ72N68
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 206TubulinInterPro annotationAdd BLAST193
Domaini208 – 326Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q72N68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRFEEETKT SPAVIKVFGV GGGGMNAVTR MSNSSLKGVE FAILNTDEQV
60 70 80 90 100
LLRSPVENKI ILGTKVTRGM GAGGDPELGL KAAEEDKERI QSIVRGSDMV
110 120 130 140 150
FITAGMGGGT GTGAAPVIAK IAKEMKCLVV GVVTLPFSFE GRRRMEFARK
160 170 180 190 200
GIEQLRSHVD TLILINNDSI FRVVDKNTPI DLAFQVIDDI LLNAVRGISD
210 220 230 240 250
IINNPGLINV DFADVKTIMR DTGDAVMGVG EGSGEGKVKE AVEYAINNSL
260 270 280 290 300
LDSTSIAGAS SLLINVSGGK DLTISDWNEV SGIITSQVDP NANIIVGLHE
310 320 330 340 350
DESLSNKIRV TVIATGFHKR GKLLQNQDSI QRGAQENYGF QRKAVGMENS
360 370 380 390 400
ALEKKDFFQD ENTEQNRNSG SLRLRSSNSS SSKVEDYDIP AYLRRNSSGP
Length:400
Mass (Da):43,068
Last modified:July 5, 2004 - v1
Checksum:iAB58B5A84D5399E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016823 Genomic DNA Translation: AAS71519.1
RefSeqiWP_000617710.1, NC_005823.1

Genome annotation databases

EnsemblBacteriaiAAS71519; AAS71519; LIC_12969
KEGGilic:LIC_12969

Similar proteinsi

Entry informationi

Entry nameiQ72N68_LEPIC
AccessioniPrimary (citable) accession number: Q72N68
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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