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Q72MT7 (G6PI_LEPIC) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:LIC_13105
OrganismLeptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130) [Complete proteome] [HAMAP]
Taxonomic identifier267671 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira

Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 445445Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180666

Sites

Active site2841Proton donor By similarity
Active site3051 By similarity
Active site4191 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q72MT7 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 5ACA2EAC6387A6A9

FASTA44549,735
        10         20         30         40         50         60 
MIRLETRFAS SFIQSSKLEP FLEKSESARL TLHSSQGQGK EYLGWLYLPK ELKNSEIERM 

        70         80         90        100        110        120 
TQVAERLRNS SEVIVVIGIG GSYLGSRAVL EATLPFFKKP SIGNPEIIFA GHHLESRYFS 

       130        140        150        160        170        180 
ELIEYLEDKN FSINVISKSG TTTEPAIAFR LLWELLRKKY GSSASSRVVA TTDSSKGVLK 

       190        200        210        220        230        240 
KFADSEKLDT FTIPDNVGGR YSVLTPVGLF PLAVAGISIS KFILGFQNIL NDIHSITDPT 

       250        260        270        280        290        300 
RNPATYYSAL RNYFLSEGRY IEVLANFNPS LRYVSEWWKQ LFGESEGKEN KGIFPASMDF 

       310        320        330        340        350        360 
TTDLHSLGQY IQEGKRILFE TVLSPSEVCS NLTLKPTQDN LDSLNFLSGN TLGYVNEQAR 

       370        380        390        400        410        420 
LGTLLAHADG GVPCLELVFP DISPQSLGEL MYFFEYSCAI SGYSLGVNPF DQPGVEAYKK 

       430        440 
NMFALLNKPG FEQEGETLRK RISRN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016823 Genomic DNA. Translation: AAS71651.1.
RefSeqYP_003014.1. NC_005823.1.

3D structure databases

ProteinModelPortalQ72MT7.
SMRQ72MT7. Positions 2-442.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267671.LIC13105.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS71651; AAS71651; LIC_13105.
GeneID2771728.
KEGGlic:LIC13105.
PATRIC22379215. VBILepInt6257_3756.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01810.
OMAAIAFREF.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycLINT267671:GHQI-3096-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_LEPIC
AccessionPrimary (citable) accession number: Q72MT7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways