Q72MR3 (Q72MR3_LEPIC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase HAMAP MF_00277
Short name=PII uridylyl-transferase HAMAP MF_00277
EC=2.7.7.59 HAMAP MF_00277

Alternative name(s):
UTase HAMAP MF_00277
Uridylyl-removing enzyme HAMAP MF_00277

Gene names

Name:	glnD HAMAP MF_00277 EMBL AAS71675.1
Ordered Locus Names:	LIC_13130

Organism

Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130) [Complete proteome] [HAMAP]

Taxonomic identifier

267671 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira

Protein attributes

Sequence length	876 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277 SAAS SAAS013546
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277 SAAS SAAS013546
Sequence similarities	Belongs to the glnD family. HAMAP MF_00277

Ontologies

Keywords
Molecular function	Nucleotidyltransferase HAMAP MF_00277 SAAS SAAS010043 EMBL AAS71675.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q72MR3 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: B2DF3A73110F1E4F	FASTA	876	100,645
	10 20 30 40 50 60 MPLQLDITYS FQRLLEKSRN IDGRLVSRQL THIVDSFILS KFESSKIGLK SGDELCIVAM 70 80 90 100 110 120 GGYGRMEMAP HSDIDLLYLH NGIKEERLET IISKINTYLY DSGKEVGHSC RTIKECFRYL 130 140 150 160 170 180 DNMSTYHAFL DARFLAGSKS LFEKFKTNFL EKLPVKLTKR YNEIKEEILT SRFLNEERPI 190 200 210 220 230 240 LLSEPNLKTD LCGLRDIQYM FWMEKPFRNL PSLSGLSILP AFQRGEIQLL QEAYDFILRV 250 260 270 280 290 300 RIAMHTITSR KTDRLDLNLQ QEVAEYLGYG KKEELSSVEK FMHVLYRHQK NIYFIIRTYL 310 320 330 340 350 360 DSILEKRGSS KGENFSYEDL NFFKIGDTVF PPTTGTLFTN PHTIYRDVML SFRMIQEKNL 370 380 390 400 410 420 QVSGTLLNEF RFASNFLDDD FKYSSEVNEE FLKILRTPSQ RGRILKLMHE SGVLGAILPE 430 440 450 460 470 480 FGACTNFPLF SYHHEYTVDE HTLLILHELD LLDRGEFQDE EIQKTYNECS KIELLALAIL 490 500 510 520 530 540 LHDAGKVKEG DHSEYGAELV VSLGDRLGLD EEDTDLCRFL VEKHTLMSEL SSKRDIGDPK 550 560 570 580 590 600 LILDFAKIVG SRERLRKLYI LTVIDTKSVG TGVLTNWKSA ILNTLYQNTI PYLAGDSKDN 610 620 630 640 650 660 FEETGPTREI QLENLKNYLI DKEDLNEEIS KSIVEFANQV VPSSYLNTVS NRKILRNFKS 670 680 690 700 710 720 IGILAQNPTF KTIFETEQDP AFVTIDVVTS NQPEILLDLS CAISSEGLSL LGMKSYALGE 730 740 750 760 770 780 YWITTVQLTD STGGGNIPQN KLDRVENKLK SISSGNLKRE SIAFQRTDWN PRKPAPESIV 790 800 810 820 830 840 NRSIQFYNED LPDVTIMEVR MPDVVGLVYR ILQIILYLDL KVCYLRVSTS ADYAYDSFYL 850 860 870 QTSNGCKLED QNLLLKLKEK ILTIQLGEQI LEEVSI

References

[1]

"Comparative genomics of two Leptospira interrogans serovars reveals novel insights into physiology and pathogenesis." Nascimento A.L.T.O., Ko A.I., Martins E.A.L., Monteiro-Vitorello C.B., Ho P.L., Haake D.A., Verjovski-Almeida S., Hartskeerl R.A., Marques M.V., Oliveira M.C., Menck C.F.M., Leite L.C.C., Carrer H., Coutinho L.L., Degrave W.M., Dellagostin O.A., El-Dorry H., Ferro E.S. , Ferro M.I.T., Furlan L.R., Gamberini M., Giglioti E.A., Goes-Neto A., Goldman G.H., Goldman M.H.S., Harakava R., Jeronimo S.M.B., Junqueira-de-Azevedo I.L.M., Kimura E.T., Kuramae E.E., Lemos E.G.M., Lemos M.V.F., Marino C.L., Nunes L.R., de Oliveira R.C., Pereira G.G., Reis M.S., Schriefer A., Siqueira W.J., Sommer P., Tsai S.M., Simpson A.J.G., Ferro J.A., Camargo L.E.A., Kitajima J.P., Setubal J.C., Van Sluys M.A. J. Bacteriol. 186:2164-2172(2004) [PubMed: 15028702] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Fiocruz L1-130.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016823 Genomic DNA. Translation: AAS71675.1.
RefSeq	YP_003038.1. NC_005823.1.
3D structure databases
ProteinModelPortal	Q72MR3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2770288.
GenomeReviews	Gene locus LIC_13130 in contig AE016823_GR.
KEGG	lic:LIC13130.
NMPDR	fig|267671.1.peg.3038.
PATRIC	22379271. VBILepInt6257_3783.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG530216.
OMA	LPHTATR.
PhylomeDB	Q72MR3.
ProtClustDB	CLSK223156.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl_transf. [Tree]
InterPro	IPR010043. GlnD_Uridyltrans. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Gene3D	G3DSA:1.10.3210.10. HD. 1 hit.
KO	K00990.
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q72MR3_LEPIC

Accession

Primary (citable) accession number: Q72MR3

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)