Q72J91 (GCP_THET2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	TT_C0888

Organism

Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [Complete proteome] [HAMAP]

Taxonomic identifier

262724 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 323	323	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303596

Sequences

	Sequence		Length	Mass (Da)
	Q72J91 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 2B448B814BE81223	FASTA	323	34,401
	10 20 30 40 50 60 MWVLGIDTSC DDTGVGLVRD GKVVVNLVAS QVRLHEAFGG VVPELASREH LKALPLLVER 70 80 90 100 110 120 ALAEAGLRPK DLDLVAATRG PGLIGALLVG YTFAKGMAFA LDRPFYAVHH LEGHIAAAWP 130 140 150 160 170 180 EGLPPPFLAL VASGGHTHLY EVLDLGRYRL LGATRDDAAG EAFDKVARLL GLGFPGGPEV 190 200 210 220 230 240 ERLAEEAEEA IPFPVPLRGQ EGYDFSFSGL KTKALHLVEK GLPKAALAKG FQEAAIAHLA 250 260 270 280 290 300 EVVLKAAKDT GHRVLLVAGG VAANRALQER FKEAGLEVHF PPRGLSQDNG AMIALAAWRR 310 320 HQRGFPPSPL SLGATAYWPL EEA

References

[1]

"The genome sequence of the extreme thermophile Thermus thermophilus." Henne A., Brueggemann H., Raasch C., Wiezer A., Hartsch T., Liesegang H., Johann A., Lienard T., Gohl O., Martinez-Arias R., Jacobi C., Starkuviene V., Schlenczeck S., Dencker S., Huber R., Klenk H.-P., Kramer W., Merkl R., Gottschalk G., Fritz H.-J. Nat. Biotechnol. 22:547-553(2004) [PubMed: 15064768] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB27 / ATCC BAA-163 / DSM 7039.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017221 Genomic DNA. Translation: AAS81232.1.
RefSeq	YP_004859.1. NC_005835.1.
3D structure databases
ProteinModelPortal	Q72J91.
ModBase	Search...
Protein-protein interaction databases
STRING	Q72J91.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2775710.
GenomeReviews	Gene locus TT_C0888 in contig AE017221_GR.
PATRIC	23952179. VBITheThe54392_0882.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	MEVIGQT.
PhylomeDB	Q72J91.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	TTHE262724:TT_C0888-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_THET2

Accession

Primary (citable) accession number: Q72J91

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program