Q72IX8 (Q72IX8_THET2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Signal peptidase I RuleBase RU003993
EC=3.4.21.89 RuleBase RU003993

Gene names

Ordered Locus Names:

TT_C1003 EMBL AAS81345.1

Organism

Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [Complete proteome] [HAMAP] EMBL AAS81345.1

Taxonomic identifier

262724 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus › Thermus thermophilus

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins. RuleBase RU003993
Sequence similarities	Belongs to the peptidase S26 family. RuleBase RU003989

Ontologies

Keywords
Molecular function	Hydrolase Protease RuleBase RU003988
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	serine-type peptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q72IX8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 0AE171AC3E776DA9	FASTA	267	30,381
	10 20 30 40 50 60 MKAFWDYLFK EWFRQVGEAL LVAFLVTTFV FTTVGVVGQS MYPTLRNGER VLVPKWETWL 70 80 90 100 110 120 VRLGFMEWRR GEIAILKPPE GTPFSTARFP VLGFSFRAFF IKRIVAVPGD EVYVDRGVVY 130 140 150 160 170 180 VNGKPLAETH ITDRITPWPD SFPGVCYEGG RLTRIVTQQG DFPVELLPAY LRPLKEMLLP 190 200 210 220 230 240 PSQETLARSE LGEVCEVGRI KLKPGYYFVM GDNRTLGGSE DSRTFGPIPV ERIAGRASFV 250 260 WWPVVVREEG GFRLNLRALA IPPAYRQ

References

[1]

"The genome sequence of the extreme thermophile Thermus thermophilus." Henne A., Brueggemann H., Raasch C., Wiezer A., Hartsch T., Liesegang H., Johann A., Lienard T., Gohl O., Martinez-Arias R., Jacobi C., Starkuviene V., Schlenczeck S., Dencker S., Huber R., Klenk H.-P., Overbeek R., Kramer W. , Merkl R., Gottschalk G., Fritz H.-J. Nat. Biotechnol. 22:547-553(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB27 / ATCC BAA-163 / DSM 7039.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017221 Genomic DNA. Translation: AAS81345.1.
RefSeq	YP_004972.1. NC_005835.1.
3D structure databases
HSSP	HSSP built from PDB template 1B12 based on UniProtKB P00803.
ProteinModelPortal	Q72IX8.
ModBase	Search...
Protein-protein interaction databases
STRING	262724.TTC1003.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAS81345; AAS81345; TT_C1003.
GeneID	2775210.
KEGG	tth:TTC1003.
PATRIC	23952407. VBITheThe54392_0996.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0681.
KO	K03100.
OMA	MPTLHNH.
ProtClustDB	CLSK738696.
Family and domain databases
Gene3D	2.10.109.10. 2 hits.
InterPro	IPR000223. Pept_S26A_signal_pept_1. IPR019757. Pept_S26A_signal_pept_1_Lys-AS. IPR019756. Pept_S26A_signal_pept_1_Ser-AS. IPR019759. Peptidase_S24_S26. IPR015927. Peptidase_S24_S26A/B/C. IPR011056. Peptidase_S24_S26A/B/C_b-rbn. [Graphical view]
PANTHER	PTHR12383. PTHR12383. 1 hit.
Pfam	PF00717. Peptidase_S24. 1 hit. [Graphical view]
PRINTS	PR00727. LEADERPTASE.
SUPFAM	SSF51306. Pept_S24_S26_C. 1 hit.
TIGRFAMs	TIGR02227. sigpep_I_bact. 1 hit.
PROSITE	PS00501. SPASE_I_1. 1 hit. PS00760. SPASE_I_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q72IX8_THET2

Accession

Primary (citable) accession number: Q72IX8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)