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Q72I09 (RL22_THET2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
50S ribosomal protein L22
Gene names
Name:rplV
Ordered Locus Names:TT_C1323
OrganismThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [Complete proteome] [HAMAP]
Taxonomic identifier262724 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus ›

Protein attributes

Sequence length113 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity. HAMAP-Rule MF_01331

The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome By similarity. HAMAP-Rule MF_01331

Subunit structure

Part of the 50S ribosomal subunit By similarity.

Sequence similarities

Belongs to the ribosomal protein L22P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentlarge ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11311350S ribosomal protein L22 HAMAP-Rule MF_01331
PRO_0000125248

Secondary structure

1 ...................... 113
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q72I09 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 11814D2DE644AF1F

FASTA11312,780
        10         20         30         40         50         60 
MEAKAIARYV RISPRKVRLV VDLIRGKSLE EARNILRYTN KRGAYFVAKV LESAAANAVN 

        70         80         90        100        110 
NHDMLEDRLY VKAAYVDEGP ALKRVLPRAR GRADIIKKRT SHITVILGEK HGK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017221 Genomic DNA. Translation: AAS81665.1.
RefSeqYP_005292.1. NC_005835.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1VSAX-ray3.71Q1-113[»]
1VSPX-ray3.83Q1-113[»]
3D5BX-ray3.21W1-113[»]
3D5DX-ray3.21W1-113[»]
3F1FX-ray3.00W1-113[»]
3F1HX-ray3.00W1-113[»]
3MRZX-ray3.62S1-112[»]
3MS1X-ray3.62S1-112[»]
3PYOX-ray3.50S1-112[»]
3PYRX-ray3.50S1-112[»]
3PYTX-ray3.40S1-112[»]
3PYVX-ray3.40S1-112[»]
ProteinModelPortalQ72I09.
SMRQ72I09. Positions 1-113.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS81665; AAS81665; TT_C1323.
GeneID2775362.
KEGGtth:TTC1323.
PATRIC23953053. VBITheThe54392_1315.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0091.
KOK02890.
OMAASRINKR.
ProtClustDBPRK00565.

Family and domain databases

Gene3D3.90.470.10. 1 hit.
HAMAPMF_01331_B. Ribosomal_L22_B.
InterProIPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view]
PANTHERPTHR13501. PTHR13501. 1 hit.
PfamPF00237. Ribosomal_L22. 1 hit.
[Graphical view]
SUPFAMSSF54843. Ribosomal_L22. 1 hit.
TIGRFAMsTIGR01044. rplV_bact. 1 hit.
PROSITEPS00464. RIBOSOMAL_L22. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ72I09.

Entry information

Entry nameRL22_THET2
AccessionPrimary (citable) accession number: Q72I09
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: July 5, 2004
Last modified: May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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