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Q72I09

- RL22_THET2

UniProt

Q72I09 - RL22_THET2

Protein

50S ribosomal protein L22

Gene

rplV

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity.UniRule annotation
    The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.UniRule annotation

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciTTHE262724:GCAT-1338-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L22UniRule annotation
    Gene namesi
    Name:rplVUniRule annotation
    Ordered Locus Names:TT_C1323
    OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
    Taxonomic identifieri262724 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000592: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. large ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 11311350S ribosomal protein L22PRO_0000125248Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit.UniRule annotation

    Structurei

    Secondary structure

    1
    113
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi6 – 127
    Helixi14 – 218
    Turni22 – 265
    Helixi29 – 3810
    Helixi42 – 6221
    Turni66 – 683
    Beta strandi70 – 734
    Beta strandi76 – 8712
    Helixi89 – 913
    Beta strandi93 – 10412
    Beta strandi106 – 1083

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1VSAX-ray3.71Q1-113[»]
    1VSPX-ray3.83Q1-113[»]
    3D5BX-ray3.21W1-113[»]
    3D5DX-ray3.21W1-113[»]
    3F1FX-ray3.00W1-113[»]
    3F1HX-ray3.00W1-113[»]
    3MRZX-ray3.62S1-112[»]
    3MS1X-ray3.62S1-112[»]
    3PYOX-ray3.50S1-112[»]
    3PYRX-ray3.50S1-112[»]
    3PYTX-ray3.40S1-112[»]
    3PYVX-ray3.40S1-112[»]
    4KBUX-ray3.86W1-113[»]
    4KBWX-ray3.86W1-113[»]
    4KCZX-ray3.50W1-113[»]
    4KD2X-ray3.50W1-113[»]
    4KD9X-ray3.50W1-113[»]
    4KDBX-ray3.50W1-113[»]
    4KDHX-ray4.00W1-113[»]
    4KDKX-ray4.00W1-113[»]
    4KFIX-ray3.40W1-112[»]
    4KFLX-ray3.40W1-112[»]
    4L6JX-ray3.40S1-112[»]
    4L6LX-ray3.40S1-112[»]
    ProteinModelPortaliQ72I09.
    SMRiQ72I09. Positions 1-113.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ72I09.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L22P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0091.
    KOiK02890.
    OMAiINRSCHI.
    OrthoDBiEOG6V4GKB.

    Family and domain databases

    Gene3Di3.90.470.10. 1 hit.
    HAMAPiMF_01331_B. Ribosomal_L22_B.
    InterProiIPR001063. Ribosomal_L22.
    IPR018260. Ribosomal_L22/L17_CS.
    IPR005727. Ribosomal_L22_bac/chlpt-type.
    [Graphical view]
    PANTHERiPTHR13501. PTHR13501. 1 hit.
    PfamiPF00237. Ribosomal_L22. 1 hit.
    [Graphical view]
    SUPFAMiSSF54843. SSF54843. 1 hit.
    TIGRFAMsiTIGR01044. rplV_bact. 1 hit.
    PROSITEiPS00464. RIBOSOMAL_L22. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q72I09-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEAKAIARYV RISPRKVRLV VDLIRGKSLE EARNILRYTN KRGAYFVAKV    50
    LESAAANAVN NHDMLEDRLY VKAAYVDEGP ALKRVLPRAR GRADIIKKRT 100
    SHITVILGEK HGK 113
    Length:113
    Mass (Da):12,780
    Last modified:July 5, 2004 - v1
    Checksum:i11814D2DE644AF1F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS81665.1.
    RefSeqiWP_011173710.1. NC_005835.1.
    YP_005292.1. NC_005835.1.

    Genome annotation databases

    EnsemblBacteriaiAAS81665; AAS81665; TT_C1323.
    GeneIDi2775362.
    KEGGitth:TTC1323.
    PATRICi23953053. VBITheThe54392_1315.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS81665.1 .
    RefSeqi WP_011173710.1. NC_005835.1.
    YP_005292.1. NC_005835.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1VSA X-ray 3.71 Q 1-113 [» ]
    1VSP X-ray 3.83 Q 1-113 [» ]
    3D5B X-ray 3.21 W 1-113 [» ]
    3D5D X-ray 3.21 W 1-113 [» ]
    3F1F X-ray 3.00 W 1-113 [» ]
    3F1H X-ray 3.00 W 1-113 [» ]
    3MRZ X-ray 3.62 S 1-112 [» ]
    3MS1 X-ray 3.62 S 1-112 [» ]
    3PYO X-ray 3.50 S 1-112 [» ]
    3PYR X-ray 3.50 S 1-112 [» ]
    3PYT X-ray 3.40 S 1-112 [» ]
    3PYV X-ray 3.40 S 1-112 [» ]
    4KBU X-ray 3.86 W 1-113 [» ]
    4KBW X-ray 3.86 W 1-113 [» ]
    4KCZ X-ray 3.50 W 1-113 [» ]
    4KD2 X-ray 3.50 W 1-113 [» ]
    4KD9 X-ray 3.50 W 1-113 [» ]
    4KDB X-ray 3.50 W 1-113 [» ]
    4KDH X-ray 4.00 W 1-113 [» ]
    4KDK X-ray 4.00 W 1-113 [» ]
    4KFI X-ray 3.40 W 1-112 [» ]
    4KFL X-ray 3.40 W 1-112 [» ]
    4L6J X-ray 3.40 S 1-112 [» ]
    4L6L X-ray 3.40 S 1-112 [» ]
    ProteinModelPortali Q72I09.
    SMRi Q72I09. Positions 1-113.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS81665 ; AAS81665 ; TT_C1323 .
    GeneIDi 2775362.
    KEGGi tth:TTC1323.
    PATRICi 23953053. VBITheThe54392_1315.

    Phylogenomic databases

    eggNOGi COG0091.
    KOi K02890.
    OMAi INRSCHI.
    OrthoDBi EOG6V4GKB.

    Enzyme and pathway databases

    BioCyci TTHE262724:GCAT-1338-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q72I09.

    Family and domain databases

    Gene3Di 3.90.470.10. 1 hit.
    HAMAPi MF_01331_B. Ribosomal_L22_B.
    InterProi IPR001063. Ribosomal_L22.
    IPR018260. Ribosomal_L22/L17_CS.
    IPR005727. Ribosomal_L22_bac/chlpt-type.
    [Graphical view ]
    PANTHERi PTHR13501. PTHR13501. 1 hit.
    Pfami PF00237. Ribosomal_L22. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54843. SSF54843. 1 hit.
    TIGRFAMsi TIGR01044. rplV_bact. 1 hit.
    PROSITEi PS00464. RIBOSOMAL_L22. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB27 / ATCC BAA-163 / DSM 7039.

    Entry informationi

    Entry nameiRL22_THET2
    AccessioniPrimary (citable) accession number: Q72I09
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 16, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3