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Q72I09

- RL22_THET2

UniProt

Q72I09 - RL22_THET2

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Protein

50S ribosomal protein L22

Gene

rplV

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).UniRule annotation
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-1338-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L22UniRule annotation
Gene namesi
Name:rplVUniRule annotation
Ordered Locus Names:TT_C1323
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000000592: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. large ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11311350S ribosomal protein L22PRO_0000125248Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Structurei

Secondary structure

1
113
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi6 – 127
Helixi14 – 218
Turni22 – 265
Helixi29 – 3810
Helixi42 – 6221
Turni66 – 683
Beta strandi70 – 734
Beta strandi76 – 8712
Helixi89 – 913
Beta strandi93 – 10412
Beta strandi106 – 1083

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VSAX-ray3.71Q1-113[»]
1VSPX-ray3.83Q1-113[»]
3D5BX-ray3.21W1-113[»]
3D5DX-ray3.21W1-113[»]
3F1FX-ray3.00W1-113[»]
3F1HX-ray3.00W1-113[»]
3MRZX-ray3.62S1-112[»]
3MS1X-ray3.62S1-112[»]
3PYOX-ray3.50S1-112[»]
3PYRX-ray3.50S1-112[»]
3PYTX-ray3.40S1-112[»]
3PYVX-ray3.40S1-112[»]
4KBUX-ray3.86W1-113[»]
4KBWX-ray3.86W1-113[»]
4KCZX-ray3.50W1-113[»]
4KD2X-ray3.50W1-113[»]
4KD9X-ray3.50W1-113[»]
4KDBX-ray3.50W1-113[»]
4KDHX-ray4.00W1-113[»]
4KDKX-ray4.00W1-113[»]
4KFIX-ray3.40W1-112[»]
4KFLX-ray3.40W1-112[»]
4L6JX-ray3.40S1-112[»]
4L6LX-ray3.40S1-112[»]
ProteinModelPortaliQ72I09.
SMRiQ72I09. Positions 1-113.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ72I09.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L22P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0091.
KOiK02890.
OMAiINRSCHI.
OrthoDBiEOG6V4GKB.

Family and domain databases

Gene3Di3.90.470.10. 1 hit.
HAMAPiMF_01331_B. Ribosomal_L22_B.
InterProiIPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view]
PANTHERiPTHR13501. PTHR13501. 1 hit.
PfamiPF00237. Ribosomal_L22. 1 hit.
[Graphical view]
SUPFAMiSSF54843. SSF54843. 1 hit.
TIGRFAMsiTIGR01044. rplV_bact. 1 hit.
PROSITEiPS00464. RIBOSOMAL_L22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q72I09-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEAKAIARYV RISPRKVRLV VDLIRGKSLE EARNILRYTN KRGAYFVAKV
60 70 80 90 100
LESAAANAVN NHDMLEDRLY VKAAYVDEGP ALKRVLPRAR GRADIIKKRT
110
SHITVILGEK HGK
Length:113
Mass (Da):12,780
Last modified:July 5, 2004 - v1
Checksum:i11814D2DE644AF1F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017221 Genomic DNA. Translation: AAS81665.1.
RefSeqiWP_011173710.1. NC_005835.1.
YP_005292.1. NC_005835.1.

Genome annotation databases

EnsemblBacteriaiAAS81665; AAS81665; TT_C1323.
GeneIDi2775362.
KEGGitth:TTC1323.
PATRICi23953053. VBITheThe54392_1315.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017221 Genomic DNA. Translation: AAS81665.1 .
RefSeqi WP_011173710.1. NC_005835.1.
YP_005292.1. NC_005835.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1VSA X-ray 3.71 Q 1-113 [» ]
1VSP X-ray 3.83 Q 1-113 [» ]
3D5B X-ray 3.21 W 1-113 [» ]
3D5D X-ray 3.21 W 1-113 [» ]
3F1F X-ray 3.00 W 1-113 [» ]
3F1H X-ray 3.00 W 1-113 [» ]
3MRZ X-ray 3.62 S 1-112 [» ]
3MS1 X-ray 3.62 S 1-112 [» ]
3PYO X-ray 3.50 S 1-112 [» ]
3PYR X-ray 3.50 S 1-112 [» ]
3PYT X-ray 3.40 S 1-112 [» ]
3PYV X-ray 3.40 S 1-112 [» ]
4KBU X-ray 3.86 W 1-113 [» ]
4KBW X-ray 3.86 W 1-113 [» ]
4KCZ X-ray 3.50 W 1-113 [» ]
4KD2 X-ray 3.50 W 1-113 [» ]
4KD9 X-ray 3.50 W 1-113 [» ]
4KDB X-ray 3.50 W 1-113 [» ]
4KDH X-ray 4.00 W 1-113 [» ]
4KDK X-ray 4.00 W 1-113 [» ]
4KFI X-ray 3.40 W 1-112 [» ]
4KFL X-ray 3.40 W 1-112 [» ]
4L6J X-ray 3.40 S 1-112 [» ]
4L6L X-ray 3.40 S 1-112 [» ]
ProteinModelPortali Q72I09.
SMRi Q72I09. Positions 1-113.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS81665 ; AAS81665 ; TT_C1323 .
GeneIDi 2775362.
KEGGi tth:TTC1323.
PATRICi 23953053. VBITheThe54392_1315.

Phylogenomic databases

eggNOGi COG0091.
KOi K02890.
OMAi INRSCHI.
OrthoDBi EOG6V4GKB.

Enzyme and pathway databases

BioCyci TTHE262724:GCAT-1338-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q72I09.

Family and domain databases

Gene3Di 3.90.470.10. 1 hit.
HAMAPi MF_01331_B. Ribosomal_L22_B.
InterProi IPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view ]
PANTHERi PTHR13501. PTHR13501. 1 hit.
Pfami PF00237. Ribosomal_L22. 1 hit.
[Graphical view ]
SUPFAMi SSF54843. SSF54843. 1 hit.
TIGRFAMsi TIGR01044. rplV_bact. 1 hit.
PROSITEi PS00464. RIBOSOMAL_L22. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB27 / ATCC BAA-163 / DSM 7039.

Entry informationi

Entry nameiRL22_THET2
AccessioniPrimary (citable) accession number: Q72I09
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: July 5, 2004
Last modified: October 1, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3