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Q72I07 (RL2_THET2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L2
Gene names
Name:rplB
Ordered Locus Names:TT_C1325
OrganismThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [Complete proteome] [HAMAP]
Taxonomic identifier262724 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome By similarity. HAMAP-Rule MF_01320

Subunit structure

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome By similarity.

Sequence similarities

Belongs to the ribosomal protein L2P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentlarge ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

transferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 27627650S ribosomal protein L2 HAMAP-Rule MF_01320
PRO_0000237259

Secondary structure

...................................................................... 276
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q72I07 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 7CF40C2BD586349B

FASTA27630,468
        10         20         30         40         50         60 
MAVKKFKPYT PSRRFMTVAD FSEITKTEPE KSLVKPLKKT GGRNNQGRIT VRFRGGGHKR 

        70         80         90        100        110        120 
LYRIIDFKRW DKVGIPAKVA AIEYDPNRSA RIALLHYVDG EKRYIIAPDG LQVGQQVVAG 

       130        140        150        160        170        180 
PDAPIQVGNA LPLRFIPVGT VVHAVELEPK KGAKLARAAG TSAQIQGREG DYVILRLPSG 

       190        200        210        220        230        240 
ELRKVHGECY ATVGAVGNAD HKNIVLGKAG RSRWLGRRPH VRGAAMNPVD HPHGGGEGRA 

       250        260        270 
PRGRPPASPW GWQTKGLKTR KRRKPSSRFI IARRKK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017221 Genomic DNA. Translation: AAS81667.1.
RefSeqYP_005294.1. NC_005835.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1VSAX-ray3.71B1-276[»]
1VSPX-ray3.83B1-276[»]
3D5BX-ray3.21D1-276[»]
3D5DX-ray3.21D1-276[»]
3F1FX-ray3.00D1-276[»]
3F1HX-ray3.00D1-276[»]
3MRZX-ray3.62C2-276[»]
3MS1X-ray3.62C2-276[»]
3PYOX-ray3.50C2-272[»]
3PYRX-ray3.50C2-272[»]
3PYTX-ray3.40C2-272[»]
3PYVX-ray3.40C2-272[»]
4KBUX-ray3.86D2-276[»]
4KBWX-ray3.86D2-276[»]
4KCZX-ray3.50D2-276[»]
4KD2X-ray3.50D2-276[»]
4KD9X-ray3.50D2-276[»]
4KDBX-ray3.50D2-276[»]
4KDHX-ray4.00D2-276[»]
4KDKX-ray4.00D2-276[»]
4KFIX-ray3.40D2-272[»]
4KFLX-ray3.40D2-272[»]
4L6JX-ray3.40D2-272[»]
4L6LX-ray3.40D2-272[»]
ProteinModelPortalQ72I07.
SMRQ72I07. Positions 2-273.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262724.TTC1325.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS81667; AAS81667; TT_C1325.
GeneID2775711.
KEGGtth:TTC1325.
PATRIC23953057. VBITheThe54392_1317.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0090.
KOK02886.
OMAVYIRINE.
OrthoDBEOG6TR0J1.

Enzyme and pathway databases

BioCycTTHE262724:GCAT-1340-MONOMER.

Family and domain databases

Gene3D2.30.30.30. 1 hit.
2.40.50.140. 1 hit.
4.10.950.10. 1 hit.
HAMAPMF_01320_B. Ribosomal_L2_B.
InterProIPR012340. NA-bd_OB-fold.
IPR022666. Rbsml_prot_L2_RNA-bd_dom.
IPR014722. Rib_L2_dom2.
IPR002171. Ribosomal_L2.
IPR005880. Ribosomal_L2_bac/org-type.
IPR022669. Ribosomal_L2_C.
IPR022671. Ribosomal_L2_CS.
IPR014726. Ribosomal_L2_dom3.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERPTHR13691. PTHR13691. 1 hit.
PTHR13691:SF5. PTHR13691:SF5. 1 hit.
PfamPF00181. Ribosomal_L2. 1 hit.
PF03947. Ribosomal_L2_C. 1 hit.
[Graphical view]
PIRSFPIRSF002158. Ribosomal_L2. 1 hit.
SUPFAMSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR01171. rplB_bact. 1 hit.
PROSITEPS00467. RIBOSOMAL_L2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ72I07.

Entry information

Entry nameRL2_THET2
AccessionPrimary (citable) accession number: Q72I07
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references