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Q72I05

- RL4_THET2

UniProt

Q72I05 - RL4_THET2

Protein

50S ribosomal protein L4

Gene

rplD

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.UniRule annotation
    Forms part of the polypeptide exit tunnel.UniRule annotation

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciTTHE262724:GCAT-1342-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L4UniRule annotation
    Gene namesi
    Name:rplDUniRule annotation
    Ordered Locus Names:TT_C1327
    OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
    Taxonomic identifieri262724 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000592: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 20520550S ribosomal protein L4PRO_0000242455Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit.

    Structurei

    Secondary structure

    1
    205
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi4 – 63
    Beta strandi13 – 153
    Helixi25 – 3814
    Beta strandi48 – 514
    Beta strandi52 – 543
    Beta strandi62 – 654
    Beta strandi73 – 753
    Beta strandi78 – 814
    Beta strandi83 – 853
    Helixi98 – 11518
    Beta strandi118 – 1214
    Turni125 – 1295
    Helixi131 – 1399
    Turni140 – 1423
    Beta strandi145 – 1473
    Beta strandi149 – 1524
    Helixi156 – 1649
    Beta strandi168 – 1714
    Helixi173 – 1753
    Helixi178 – 1814
    Beta strandi184 – 1907
    Helixi191 – 20010

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1VSAX-ray3.71D1-205[»]
    1VSPX-ray3.83D1-205[»]
    3D5BX-ray3.21F1-205[»]
    3D5DX-ray3.21F1-205[»]
    3MRZX-ray3.62E1-205[»]
    3MS1X-ray3.62E1-205[»]
    3PYOX-ray3.50E1-202[»]
    3PYRX-ray3.50E1-202[»]
    3PYTX-ray3.40E1-202[»]
    3PYVX-ray3.40E1-202[»]
    4KBUX-ray3.86F1-203[»]
    4KBWX-ray3.86F1-203[»]
    4KCZX-ray3.50F1-203[»]
    4KD2X-ray3.50F1-203[»]
    4KD9X-ray3.50F1-203[»]
    4KDBX-ray3.50F1-203[»]
    4KDHX-ray4.00F1-203[»]
    4KDKX-ray4.00F1-203[»]
    4KFIX-ray3.40F1-202[»]
    4KFLX-ray3.40F1-202[»]
    4L6JX-ray3.40F1-202[»]
    4L6LX-ray3.40F1-202[»]
    ProteinModelPortaliQ72I05.
    SMRiQ72I05. Positions 4-197.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ72I05.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L4P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0088.
    KOiK02926.
    OMAiRSIMANQ.
    OrthoDBiEOG6M0T9G.

    Family and domain databases

    Gene3Di3.40.1370.10. 1 hit.
    HAMAPiMF_01328_B. Ribosomal_L4_B.
    InterProiIPR002136. Ribosomal_L4/L1e.
    IPR013005. Ribosomal_L4/L1e_bac-type.
    IPR023574. Ribosomal_L4_dom.
    [Graphical view]
    PANTHERiPTHR10746. PTHR10746. 1 hit.
    PfamiPF00573. Ribosomal_L4. 1 hit.
    [Graphical view]
    SUPFAMiSSF52166. SSF52166. 1 hit.
    TIGRFAMsiTIGR03953. rplD_bact. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q72I05-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYQIPVLSPS GRRELAADLP AEINPHLLWE VVRWQLAKRR RGTASTKTRG    50
    EVAYSGRKIW PQKHTGRARH GDIGAPIFVG GGVVFGPKPR DYSYTLPKKV 100
    RKKGLAMAVA DRAREGKLLL VEAFAGVNGK TKEFLAWAKE AGLDGSESVL 150
    LVTGNELVRR AARNLPWVVT LAPEGLNVYD IVRTERLVMD LDAWEVFQNR 200
    IGGEA 205
    Length:205
    Mass (Da):22,708
    Last modified:July 5, 2004 - v1
    Checksum:iFC50A700F8CBC324
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS81669.1.
    RefSeqiYP_005296.1. NC_005835.1.

    Genome annotation databases

    EnsemblBacteriaiAAS81669; AAS81669; TT_C1327.
    GeneIDi2776371.
    KEGGitth:TTC1327.
    PATRICi23953061. VBITheThe54392_1319.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS81669.1 .
    RefSeqi YP_005296.1. NC_005835.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1VSA X-ray 3.71 D 1-205 [» ]
    1VSP X-ray 3.83 D 1-205 [» ]
    3D5B X-ray 3.21 F 1-205 [» ]
    3D5D X-ray 3.21 F 1-205 [» ]
    3MRZ X-ray 3.62 E 1-205 [» ]
    3MS1 X-ray 3.62 E 1-205 [» ]
    3PYO X-ray 3.50 E 1-202 [» ]
    3PYR X-ray 3.50 E 1-202 [» ]
    3PYT X-ray 3.40 E 1-202 [» ]
    3PYV X-ray 3.40 E 1-202 [» ]
    4KBU X-ray 3.86 F 1-203 [» ]
    4KBW X-ray 3.86 F 1-203 [» ]
    4KCZ X-ray 3.50 F 1-203 [» ]
    4KD2 X-ray 3.50 F 1-203 [» ]
    4KD9 X-ray 3.50 F 1-203 [» ]
    4KDB X-ray 3.50 F 1-203 [» ]
    4KDH X-ray 4.00 F 1-203 [» ]
    4KDK X-ray 4.00 F 1-203 [» ]
    4KFI X-ray 3.40 F 1-202 [» ]
    4KFL X-ray 3.40 F 1-202 [» ]
    4L6J X-ray 3.40 F 1-202 [» ]
    4L6L X-ray 3.40 F 1-202 [» ]
    ProteinModelPortali Q72I05.
    SMRi Q72I05. Positions 4-197.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS81669 ; AAS81669 ; TT_C1327 .
    GeneIDi 2776371.
    KEGGi tth:TTC1327.
    PATRICi 23953061. VBITheThe54392_1319.

    Phylogenomic databases

    eggNOGi COG0088.
    KOi K02926.
    OMAi RSIMANQ.
    OrthoDBi EOG6M0T9G.

    Enzyme and pathway databases

    BioCyci TTHE262724:GCAT-1342-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q72I05.

    Family and domain databases

    Gene3Di 3.40.1370.10. 1 hit.
    HAMAPi MF_01328_B. Ribosomal_L4_B.
    InterProi IPR002136. Ribosomal_L4/L1e.
    IPR013005. Ribosomal_L4/L1e_bac-type.
    IPR023574. Ribosomal_L4_dom.
    [Graphical view ]
    PANTHERi PTHR10746. PTHR10746. 1 hit.
    Pfami PF00573. Ribosomal_L4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52166. SSF52166. 1 hit.
    TIGRFAMsi TIGR03953. rplD_bact. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB27 / ATCC BAA-163 / DSM 7039.

    Entry informationi

    Entry nameiRL4_THET2
    AccessioniPrimary (citable) accession number: Q72I05
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3