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Protein

50S ribosomal protein L3

Gene

rplC

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L3UniRule annotation
Gene namesi
Name:rplCUniRule annotation
Ordered Locus Names:TT_C1328
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000592 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002414281 – 20650S ribosomal protein L3Add BLAST206

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.UniRule annotation

Protein-protein interaction databases

STRINGi262724.TTC1328.

Structurei

Secondary structure

1206
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 16Combined sources14
Beta strandi19 – 27Combined sources9
Beta strandi31 – 37Combined sources7
Turni39 – 41Combined sources3
Beta strandi42 – 44Combined sources3
Beta strandi46 – 53Combined sources8
Turni56 – 62Combined sources7
Helixi63 – 68Combined sources6
Turni69 – 71Combined sources3
Beta strandi75 – 82Combined sources8
Beta strandi88 – 91Combined sources4
Helixi93 – 95Combined sources3
Beta strandi98 – 100Combined sources3
Beta strandi101 – 107Combined sources7
Beta strandi110 – 113Combined sources4
Helixi116 – 119Combined sources4
Beta strandi127 – 130Combined sources4
Turni133 – 136Combined sources4
Turni145 – 147Combined sources3
Beta strandi159 – 176Combined sources18
Turni177 – 180Combined sources4
Beta strandi181 – 184Combined sources4
Beta strandi194 – 200Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V4IX-ray3.71C1-206[»]
4V4JX-ray3.83C1-206[»]
4V63X-ray3.21BE/DE1-206[»]
4V67X-ray3.00BE/DE1-206[»]
4V7PX-ray3.62BD/CD1-206[»]
4V83X-ray3.50BD/DD1-204[»]
4V84X-ray3.40BD/DD1-204[»]
4V9JX-ray3.86BE/DE1-205[»]
4V9KX-ray3.50BE/DE1-205[»]
4V9LX-ray3.50BE/DE1-205[»]
4V9MX-ray4.00BE/DE1-205[»]
4V9NX-ray3.40BE/DE1-204[»]
4V9QX-ray3.40AE/CE1-204[»]
4W29X-ray3.80BE/DE1-205[»]
4XEJX-ray3.80AL03/BL031-204[»]
5J4DX-ray3.10F/KB1-206[»]
ProteinModelPortaliQ72I04.
SMRiQ72I04.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ72I04.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L3P family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EEE. Bacteria.
COG0087. LUCA.
KOiK02906.
OMAiKRMAGRY.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B. 1 hit.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q72I04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGILGVKVG MTRIFRDDRA VPVTVILAGP CPVVQRRTPE KDGYTAVQLG
60 70 80 90 100
FLPQNPKRVN RPLKGHFAKA GVEPVRILRE IRDFNPEGDT VTVEIFKPGE
110 120 130 140 150
RVDVTGTSKG RGFAGVMKRW NFAGGPDSHG AHKIHRHPGS IGNRKTPGRV
160 170 180 190 200
YKGKKMAGHY GAERVTVMNL EVVDVIPEEN LLLVKGAVPG PNGGLVIVRE

TKKAAK
Length:206
Mass (Da):22,408
Last modified:July 5, 2004 - v1
Checksum:iA920741478CB6028
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017221 Genomic DNA. Translation: AAS81670.1.
RefSeqiWP_011173714.1. NC_005835.1.

Genome annotation databases

EnsemblBacteriaiAAS81670; AAS81670; TT_C1328.
KEGGitth:TT_C1328.
PATRICi23953063. VBITheThe54392_1320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017221 Genomic DNA. Translation: AAS81670.1.
RefSeqiWP_011173714.1. NC_005835.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V4IX-ray3.71C1-206[»]
4V4JX-ray3.83C1-206[»]
4V63X-ray3.21BE/DE1-206[»]
4V67X-ray3.00BE/DE1-206[»]
4V7PX-ray3.62BD/CD1-206[»]
4V83X-ray3.50BD/DD1-204[»]
4V84X-ray3.40BD/DD1-204[»]
4V9JX-ray3.86BE/DE1-205[»]
4V9KX-ray3.50BE/DE1-205[»]
4V9LX-ray3.50BE/DE1-205[»]
4V9MX-ray4.00BE/DE1-205[»]
4V9NX-ray3.40BE/DE1-204[»]
4V9QX-ray3.40AE/CE1-204[»]
4W29X-ray3.80BE/DE1-205[»]
4XEJX-ray3.80AL03/BL031-204[»]
5J4DX-ray3.10F/KB1-206[»]
ProteinModelPortaliQ72I04.
SMRiQ72I04.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi262724.TTC1328.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS81670; AAS81670; TT_C1328.
KEGGitth:TT_C1328.
PATRICi23953063. VBITheThe54392_1320.

Phylogenomic databases

eggNOGiENOG4105EEE. Bacteria.
COG0087. LUCA.
KOiK02906.
OMAiKRMAGRY.

Miscellaneous databases

EvolutionaryTraceiQ72I04.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B. 1 hit.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL3_THET2
AccessioniPrimary (citable) accession number: Q72I04
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.