Q72H17 (Q72H17_THET2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Name:	fabL EMBL AAS82020.1
Ordered Locus Names:	TT_C1678

Organism

Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [Complete proteome] [HAMAP]

Taxonomic identifier

262724 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	261 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL AAS82020.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	157	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	Q72H17 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4B8D51F6FD269586	FASTA	261	28,040
	10 20 30 40 50 60 MLTVDLSGKK ALVMGVTNQR SLGFAIAAKL KEAGAEVALS YQAERLRPEA EKLAEALGGA 70 80 90 100 110 120 LLFRADVTQD EELDALFAGV KEAFGGLDYL VHAIAFAPRE AMEGRYIDTR RQDWLLALEV 130 140 150 160 170 180 SAYSLVAAAQ RAEPLLREGG GIVTLTYYAS EKVVPKYNVM AIAKAALEAS VRYLAYELGP 190 200 210 220 230 240 KGVRVNAISA GPVRTVAARS IPGFTKMYDR VAQTAPLRRN VTQEEVGNLG LFLLSPLASG 250 260 ITGEVVYVDA GYHIMGMELE G

References

[1]

"The genome sequence of the extreme thermophile Thermus thermophilus." Henne A., Brueggemann H., Raasch C., Wiezer A., Hartsch T., Liesegang H., Johann A., Lienard T., Gohl O., Martinez-Arias R., Jacobi C., Starkuviene V., Schlenczeck S., Dencker S., Huber R., Klenk H.-P., Kramer W., Merkl R., Gottschalk G., Fritz H.-J. Nat. Biotechnol. 22:547-553(2004) [PubMed: 15064768] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017221 Genomic DNA. Translation: AAS82020.1.
RefSeq	YP_005647.1. NC_005835.1.
3D structure databases
HSSP	HSSP built from PDB template 1AHI based on UniProtKB P25529.
ProteinModelPortal	Q72H17.
SMR	Q72H17. Positions 1-257.
ModBase	Search...
Protein-protein interaction databases
STRING	Q72H17.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2776080.
GenomeReviews	Gene locus TT_C1678 in contig AE017221_GR.
PATRIC	23953809. VBITheThe54392_1675.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0623.
HOGENOM	HBG750976.
OMA	MGVANNR.
PhylomeDB	Q72H17.
ProtClustDB	CLSK445334.
Enzyme and pathway databases
BioCyc	TTHE262724:TT_C1678-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

Q72H17_THET2

Accession

Primary (citable) accession number: Q72H17

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)