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Q72GY6

- G6PI_THET2

UniProt

Q72GY6 - G6PI_THET2

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 2 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei266 – 2661Proton donorPROSITE-ProRule annotation
    Active sitei292 – 2921PROSITE-ProRule annotation
    Active sitei405 – 4051PROSITE-ProRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-KW
    2. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciTTHE262724:GCAT-1743-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomerase (EC:5.3.1.9)
    Short name:
    GPI
    Alternative name(s):
    Phosphoglucose isomerase
    Short name:
    PGI
    Phosphohexose isomerase
    Short name:
    PHI
    Gene namesi
    Name:pgi
    Ordered Locus Names:TT_C1710
    OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
    Taxonomic identifieri262724 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000592: Chromosome

    Subcellular locationi

    Cytoplasm PROSITE-ProRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 414414Glucose-6-phosphate isomerasePRO_0000180758Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi262724.TTC1710.

    Structurei

    3D structure databases

    ProteinModelPortaliQ72GY6.
    SMRiQ72GY6. Positions 1-414.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    KOiK01810.
    OMAiANMFKIL.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q72GY6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLDTRFLSG FPEALSRHGP LLEEARRRLL AKRGEPGSML GWMDLPEDTE    50
    TLREVRRYRE ANPWVEDFVL IGIGGSALGP KALEAAFNES GVRFHYLDHV 100
    EPEPTLRLLR TLDPRKTLVN AVSKSGSTAE TLAGLAVFLK WLKAHLGEDW 150
    RRHLVVTTDP KEGPLRAFAE REGLKAFAIP KEVGGRFSAL SPVGLLPLAF 200
    AGADLDALLM GARKANETAL APLEESLPLK TALLLHLHRH LPVHVFMVYS 250
    ERLSHLPSWF VQLHDESLGK VDRQGQRVGT TAVPALGPKD QHAQVQLFRE 300
    GPLDKLLALV IPEAPLEDVE IPEVGGLEAA SYLFGKTLFQ LLKAEAEATY 350
    EALAEAGQRV YALFLPEVSP YAVGWLMQHL MWQTAFLGEL WEVNAFDQPG 400
    VELGKVLTRK RLAG 414
    Length:414
    Mass (Da):45,874
    Last modified:November 8, 2005 - v2
    Checksum:i4FA0470FE42B302C
    GO

    Sequence cautioni

    The sequence AAS82052.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS82052.1. Different initiation.
    RefSeqiYP_005679.1. NC_005835.1.

    Genome annotation databases

    EnsemblBacteriaiAAS82052; AAS82052; TT_C1710.
    GeneIDi2776117.
    KEGGitth:TTC1710.
    PATRICi23953877. VBITheThe54392_1709.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS82052.1 . Different initiation.
    RefSeqi YP_005679.1. NC_005835.1.

    3D structure databases

    ProteinModelPortali Q72GY6.
    SMRi Q72GY6. Positions 1-414.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262724.TTC1710.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS82052 ; AAS82052 ; TT_C1710 .
    GeneIDi 2776117.
    KEGGi tth:TTC1710.
    PATRICi 23953877. VBITheThe54392_1709.

    Phylogenomic databases

    eggNOGi COG0166.
    KOi K01810.
    OMAi ANMFKIL.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci TTHE262724:GCAT-1743-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB27 / ATCC BAA-163 / DSM 7039.

    Entry informationi

    Entry nameiG6PI_THET2
    AccessioniPrimary (citable) accession number: Q72GY6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2005
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 65 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3