Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q72GV9

- RL1_THET2

UniProt

Q72GV9 - RL1_THET2

Protein

50S ribosomal protein L1

Gene

rplA

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.UniRule annotation
    Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.UniRule annotation

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro
    3. tRNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of translation Source: UniProtKB-KW
    2. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Repressor, Ribonucleoprotein, Ribosomal protein

    Keywords - Biological processi

    Translation regulation

    Keywords - Ligandi

    RNA-binding, rRNA-binding, tRNA-binding

    Enzyme and pathway databases

    BioCyciTTHE262724:GCAT-1776-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L1UniRule annotation
    Gene namesi
    Name:rplAUniRule annotation
    Ordered Locus Names:TT_C1739
    OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
    Taxonomic identifieri262724 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000592: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. large ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 22922850S ribosomal protein L1PRO_0000125763Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit.UniRule annotation

    Structurei

    Secondary structure

    1
    229
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi7 – 104
    Turni11 – 177
    Helixi24 – 329
    Beta strandi36 – 383
    Helixi51 – 533
    Beta strandi54 – 563
    Helixi82 – 876
    Turni97 – 10711
    Helixi119 – 1268
    Turni129 – 1368
    Helixi140 – 1423
    Beta strandi146 – 1483
    Turni149 – 1513
    Helixi152 – 1598
    Turni167 – 1693
    Turni178 – 1803
    Helixi183 – 19917
    Beta strandi218 – 2203
    Helixi226 – 2283

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1VSAX-ray3.71A1-229[»]
    1VSPX-ray3.83A1-229[»]
    4BYNelectron microscopy4.30y1-229[»]
    4BYQelectron microscopy4.30L1-229[»]
    4KBUX-ray3.86C2-229[»]
    4KBWX-ray3.86C2-229[»]
    4KCZX-ray3.50C2-229[»]
    4KD2X-ray3.50C2-229[»]
    4KD9X-ray3.50C2-229[»]
    4KDBX-ray3.50C2-229[»]
    4KDHX-ray4.00C2-229[»]
    4KDKX-ray4.00C2-229[»]
    ProteinModelPortaliQ72GV9.
    SMRiQ72GV9. Positions 2-229.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ72GV9.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L1P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0081.
    KOiK02863.
    OMAiGRYWRSI.
    OrthoDBiEOG6FBX2G.

    Family and domain databases

    Gene3Di3.30.190.20. 2 hits.
    3.40.50.790. 1 hit.
    HAMAPiMF_01318_B. Ribosomal_L1_B.
    InterProiIPR005878. Ribosom_L1_bac-type.
    IPR002143. Ribosomal_L1.
    IPR023674. Ribosomal_L1-like.
    IPR028364. Ribosomal_L1/biogenesis.
    IPR016094. Ribosomal_L1_2-a/b-sand.
    IPR016095. Ribosomal_L1_3-a/b-sand.
    IPR023673. Ribosomal_L1_CS.
    [Graphical view]
    PfamiPF00687. Ribosomal_L1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002155. Ribosomal_L1. 1 hit.
    SUPFAMiSSF56808. SSF56808. 1 hit.
    TIGRFAMsiTIGR01169. rplA_bact. 1 hit.
    PROSITEiPS01199. RIBOSOMAL_L1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q72GV9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPKHGKRYRA LLEKVDPNKI YTIDEAAHLV KELATAKFDE TVEVHAKLGI    50
    DPRRSDQNVR GTVSLPHGLG KQVRVLAIAK GEKIKEAEEA GADYVGGEEI 100
    IQKILDGWMD FDAVVATPDV MGAVGSKLGR ILGPRGLLPN PKAGTVGFNI 150
    GEIIREIKAG RIEFRNDKTG AIHAPVGKAS FPPEKLADNI RAFIRALEAH 200
    KPEGAKGTFL RSVYVTTTMG PSVRINPHS 229
    Length:229
    Mass (Da):24,826
    Last modified:January 23, 2007 - v3
    Checksum:i38C14B2563718175
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS82081.1.
    RefSeqiYP_005708.1. NC_005835.1.

    Genome annotation databases

    EnsemblBacteriaiAAS82081; AAS82081; TT_C1739.
    GeneIDi2775643.
    KEGGitth:TTC1739.
    PATRICi23953943. VBITheThe54392_1738.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS82081.1 .
    RefSeqi YP_005708.1. NC_005835.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1VSA X-ray 3.71 A 1-229 [» ]
    1VSP X-ray 3.83 A 1-229 [» ]
    4BYN electron microscopy 4.30 y 1-229 [» ]
    4BYQ electron microscopy 4.30 L 1-229 [» ]
    4KBU X-ray 3.86 C 2-229 [» ]
    4KBW X-ray 3.86 C 2-229 [» ]
    4KCZ X-ray 3.50 C 2-229 [» ]
    4KD2 X-ray 3.50 C 2-229 [» ]
    4KD9 X-ray 3.50 C 2-229 [» ]
    4KDB X-ray 3.50 C 2-229 [» ]
    4KDH X-ray 4.00 C 2-229 [» ]
    4KDK X-ray 4.00 C 2-229 [» ]
    ProteinModelPortali Q72GV9.
    SMRi Q72GV9. Positions 2-229.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS82081 ; AAS82081 ; TT_C1739 .
    GeneIDi 2775643.
    KEGGi tth:TTC1739.
    PATRICi 23953943. VBITheThe54392_1738.

    Phylogenomic databases

    eggNOGi COG0081.
    KOi K02863.
    OMAi GRYWRSI.
    OrthoDBi EOG6FBX2G.

    Enzyme and pathway databases

    BioCyci TTHE262724:GCAT-1776-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q72GV9.

    Family and domain databases

    Gene3Di 3.30.190.20. 2 hits.
    3.40.50.790. 1 hit.
    HAMAPi MF_01318_B. Ribosomal_L1_B.
    InterProi IPR005878. Ribosom_L1_bac-type.
    IPR002143. Ribosomal_L1.
    IPR023674. Ribosomal_L1-like.
    IPR028364. Ribosomal_L1/biogenesis.
    IPR016094. Ribosomal_L1_2-a/b-sand.
    IPR016095. Ribosomal_L1_3-a/b-sand.
    IPR023673. Ribosomal_L1_CS.
    [Graphical view ]
    Pfami PF00687. Ribosomal_L1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002155. Ribosomal_L1. 1 hit.
    SUPFAMi SSF56808. SSF56808. 1 hit.
    TIGRFAMsi TIGR01169. rplA_bact. 1 hit.
    PROSITEi PS01199. RIBOSOMAL_L1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB27 / ATCC BAA-163 / DSM 7039.

    Entry informationi

    Entry nameiRL1_THET2
    AccessioniPrimary (citable) accession number: Q72GV9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 15, 2005
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 74 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3