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Q72GV9

- RL1_THET2

UniProt

Q72GV9 - RL1_THET2

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Protein

50S ribosomal protein L1

Gene
rplA, TT_C1739
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity.UniRule annotation
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro
  3. tRNA binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of translation Source: UniProtKB-KW
  2. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Repressor, Ribonucleoprotein, Ribosomal protein

Keywords - Biological processi

Translation regulation

Keywords - Ligandi

RNA-binding, rRNA-binding, tRNA-binding

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-1776-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L1
Gene namesi
Name:rplA
Ordered Locus Names:TT_C1739
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000000592: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. large ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 22922850S ribosomal protein L1UniRule annotationPRO_0000125763Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit By similarity.UniRule annotation

Structurei

Secondary structure

1
229
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 104
Turni11 – 177
Helixi24 – 329
Beta strandi36 – 383
Helixi51 – 533
Beta strandi54 – 563
Helixi82 – 876
Turni97 – 10711
Helixi119 – 1268
Turni129 – 1368
Helixi140 – 1423
Beta strandi146 – 1483
Turni149 – 1513
Helixi152 – 1598
Turni167 – 1693
Turni178 – 1803
Helixi183 – 19917
Beta strandi218 – 2203
Helixi226 – 2283

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VSAX-ray3.71A1-229[»]
1VSPX-ray3.83A1-229[»]
4BYNelectron microscopy4.30y1-229[»]
4BYQelectron microscopy4.30L1-229[»]
4KBUX-ray3.86C2-229[»]
4KBWX-ray3.86C2-229[»]
4KCZX-ray3.50C2-229[»]
4KD2X-ray3.50C2-229[»]
4KD9X-ray3.50C2-229[»]
4KDBX-ray3.50C2-229[»]
4KDHX-ray4.00C2-229[»]
4KDKX-ray4.00C2-229[»]
ProteinModelPortaliQ72GV9.
SMRiQ72GV9. Positions 2-229.

Miscellaneous databases

EvolutionaryTraceiQ72GV9.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0081.
KOiK02863.
OMAiGRYWRSI.
OrthoDBiEOG6FBX2G.

Family and domain databases

Gene3Di3.30.190.20. 2 hits.
3.40.50.790. 1 hit.
HAMAPiMF_01318_B. Ribosomal_L1_B.
InterProiIPR005878. Ribosom_L1_bac-type.
IPR002143. Ribosomal_L1.
IPR023674. Ribosomal_L1-like.
IPR028364. Ribosomal_L1/biogenesis.
IPR016094. Ribosomal_L1_2-a/b-sand.
IPR016095. Ribosomal_L1_3-a/b-sand.
IPR023673. Ribosomal_L1_CS.
[Graphical view]
PfamiPF00687. Ribosomal_L1. 1 hit.
[Graphical view]
PIRSFiPIRSF002155. Ribosomal_L1. 1 hit.
SUPFAMiSSF56808. SSF56808. 1 hit.
TIGRFAMsiTIGR01169. rplA_bact. 1 hit.
PROSITEiPS01199. RIBOSOMAL_L1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q72GV9-1 [UniParc]FASTAAdd to Basket

« Hide

MPKHGKRYRA LLEKVDPNKI YTIDEAAHLV KELATAKFDE TVEVHAKLGI    50
DPRRSDQNVR GTVSLPHGLG KQVRVLAIAK GEKIKEAEEA GADYVGGEEI 100
IQKILDGWMD FDAVVATPDV MGAVGSKLGR ILGPRGLLPN PKAGTVGFNI 150
GEIIREIKAG RIEFRNDKTG AIHAPVGKAS FPPEKLADNI RAFIRALEAH 200
KPEGAKGTFL RSVYVTTTMG PSVRINPHS 229
Length:229
Mass (Da):24,826
Last modified:January 23, 2007 - v3
Checksum:i38C14B2563718175
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017221 Genomic DNA. Translation: AAS82081.1.
RefSeqiYP_005708.1. NC_005835.1.

Genome annotation databases

EnsemblBacteriaiAAS82081; AAS82081; TT_C1739.
GeneIDi2775643.
KEGGitth:TTC1739.
PATRICi23953943. VBITheThe54392_1738.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017221 Genomic DNA. Translation: AAS82081.1 .
RefSeqi YP_005708.1. NC_005835.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1VSA X-ray 3.71 A 1-229 [» ]
1VSP X-ray 3.83 A 1-229 [» ]
4BYN electron microscopy 4.30 y 1-229 [» ]
4BYQ electron microscopy 4.30 L 1-229 [» ]
4KBU X-ray 3.86 C 2-229 [» ]
4KBW X-ray 3.86 C 2-229 [» ]
4KCZ X-ray 3.50 C 2-229 [» ]
4KD2 X-ray 3.50 C 2-229 [» ]
4KD9 X-ray 3.50 C 2-229 [» ]
4KDB X-ray 3.50 C 2-229 [» ]
4KDH X-ray 4.00 C 2-229 [» ]
4KDK X-ray 4.00 C 2-229 [» ]
ProteinModelPortali Q72GV9.
SMRi Q72GV9. Positions 2-229.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS82081 ; AAS82081 ; TT_C1739 .
GeneIDi 2775643.
KEGGi tth:TTC1739.
PATRICi 23953943. VBITheThe54392_1738.

Phylogenomic databases

eggNOGi COG0081.
KOi K02863.
OMAi GRYWRSI.
OrthoDBi EOG6FBX2G.

Enzyme and pathway databases

BioCyci TTHE262724:GCAT-1776-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q72GV9.

Family and domain databases

Gene3Di 3.30.190.20. 2 hits.
3.40.50.790. 1 hit.
HAMAPi MF_01318_B. Ribosomal_L1_B.
InterProi IPR005878. Ribosom_L1_bac-type.
IPR002143. Ribosomal_L1.
IPR023674. Ribosomal_L1-like.
IPR028364. Ribosomal_L1/biogenesis.
IPR016094. Ribosomal_L1_2-a/b-sand.
IPR016095. Ribosomal_L1_3-a/b-sand.
IPR023673. Ribosomal_L1_CS.
[Graphical view ]
Pfami PF00687. Ribosomal_L1. 1 hit.
[Graphical view ]
PIRSFi PIRSF002155. Ribosomal_L1. 1 hit.
SUPFAMi SSF56808. SSF56808. 1 hit.
TIGRFAMsi TIGR01169. rplA_bact. 1 hit.
PROSITEi PS01199. RIBOSOMAL_L1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB27 / ATCC BAA-163 / DSM 7039.

Entry informationi

Entry nameiRL1_THET2
AccessioniPrimary (citable) accession number: Q72GV9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 73 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi