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Q72GJ6

- Q72GJ6_THET2

UniProt

Q72GJ6 - Q72GJ6_THET2

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Protein
Submitted name: Bacterial peptide chain release factor 2 (RF-2)
Gene
TT_C1852
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA By similarity.SAAS annotations

GO - Molecular functioni

  1. translation release factor activity, codon specific Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Protein biosynthesisSAAS annotations

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-1891-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Bacterial peptide chain release factor 2 (RF-2)Imported
Gene namesi
Ordered Locus Names:TT_C1852Imported
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)Imported
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000000592: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi262724.TTC1852.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3F1EX-ray3.00X1-378[»]
3F1GX-ray3.00X1-378[»]
4KFHX-ray3.40Y17-378[»]
4KFKX-ray3.40Y17-378[»]
ProteinModelPortaliQ72GJ6.
SMRiQ72GJ6. Positions 27-369.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1186.
KOiK02836.
OMAiCYVDIQS.
OrthoDBiEOG6TN48J.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004374. PrfB.
[Graphical view]
PANTHERiPTHR11075:SF6. PTHR11075:SF6. 1 hit.
PfamiPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTiSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00020. prfB. 1 hit.
PROSITEiPS00745. RF_PROK_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q72GJ6-1 [UniParc]FASTAAdd to Basket

« Hide

MRLASQSAIL VKVWTWNASR NAWKASGGIF DIPQKETRLK ELERRLEDPS    50
LWNDPEAARK VSQEAARLRR TVDTFRSLES DLQGLLELME ELPAEEREAL 100
KPELEEAAKK LDELYHQTLL NFPHAEKNAI LTIQPGAGGT EACDWAEMLL 150
RMYTRFAERQ GFQVEVVDLT PGPEAGIDYA QILVKGENAY GLLSPEAGVH 200
RLVRPSPFDA SGRRHTSFAG VEVIPEVDEE VEVVLKPEEL RIDVMRASGP 250
GGQGVNTTDS AVRVVHLPTG ITVTCQTTRS QIKNKELALK ILKARLYELE 300
RKKREEELKA LRGEVRPIEW GSQIRSYVLD KNYVKDHRTG LMRHDPENVL 350
DGDLMDLIWA GLEWKAGRRQ GTEEVEAE 378
Length:378
Mass (Da):42,734
Last modified:July 5, 2004 - v1
Checksum:i55B4AC9C891AEEB7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017221 Genomic DNA. Translation: AAS82194.1.
RefSeqiYP_005821.1. NC_005835.1.

Genome annotation databases

EnsemblBacteriaiAAS82194; AAS82194; TT_C1852.
GeneIDi2776319.
KEGGitth:TTC1852.
PATRICi23954173. VBITheThe54392_1851.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017221 Genomic DNA. Translation: AAS82194.1 .
RefSeqi YP_005821.1. NC_005835.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3F1E X-ray 3.00 X 1-378 [» ]
3F1G X-ray 3.00 X 1-378 [» ]
4KFH X-ray 3.40 Y 17-378 [» ]
4KFK X-ray 3.40 Y 17-378 [» ]
ProteinModelPortali Q72GJ6.
SMRi Q72GJ6. Positions 27-369.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 262724.TTC1852.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS82194 ; AAS82194 ; TT_C1852 .
GeneIDi 2776319.
KEGGi tth:TTC1852.
PATRICi 23954173. VBITheThe54392_1851.

Phylogenomic databases

eggNOGi COG1186.
KOi K02836.
OMAi CYVDIQS.
OrthoDBi EOG6TN48J.

Enzyme and pathway databases

BioCyci TTHE262724:GCAT-1891-MONOMER.

Family and domain databases

Gene3Di 3.30.160.20. 1 hit.
InterProi IPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004374. PrfB.
[Graphical view ]
PANTHERi PTHR11075:SF6. PTHR11075:SF6. 1 hit.
Pfami PF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view ]
SMARTi SM00937. PCRF. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00020. prfB. 1 hit.
PROSITEi PS00745. RF_PROK_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB27 / ATCC BAA-163 / DSM 7039.
  2. Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS).
  3. "Crystal structure of the 70S ribosome bound with the Q253P mutant form of release factor RF2."
    Santos N., Zhu J., Donohue J.P., Korostelev A.A., Noller H.F.
    Structure 21:1258-1263(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.40 ANGSTROMS) OF 17-378.

Entry informationi

Entry nameiQ72GJ6_THET2
AccessioniPrimary (citable) accession number: Q72GJ6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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