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Q72GJ6 (Q72GJ6_THET2) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Ordered Locus Names:TT_C1852 EMBL AAS82194.1
OrganismThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [Complete proteome] [HAMAP] EMBL AAS82194.1
Taxonomic identifier262724 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length378 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA By similarity. SAAS SAAS004374

Subcellular location

Cytoplasm By similarity.

Ontologies

Keywords
   Biological processProtein biosynthesis SAAS SAAS004374
   Cellular componentCytoplasm SAAS SAAS004374
   Technical term3D-structure PDB 3F1E PDB 3F1G PDB 4KFK PDB 4KFH
Complete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation release factor activity, codon specific

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q72GJ6 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 55B4AC9C891AEEB7

FASTA37842,734
        10         20         30         40         50         60 
MRLASQSAIL VKVWTWNASR NAWKASGGIF DIPQKETRLK ELERRLEDPS LWNDPEAARK 

        70         80         90        100        110        120 
VSQEAARLRR TVDTFRSLES DLQGLLELME ELPAEEREAL KPELEEAAKK LDELYHQTLL 

       130        140        150        160        170        180 
NFPHAEKNAI LTIQPGAGGT EACDWAEMLL RMYTRFAERQ GFQVEVVDLT PGPEAGIDYA 

       190        200        210        220        230        240 
QILVKGENAY GLLSPEAGVH RLVRPSPFDA SGRRHTSFAG VEVIPEVDEE VEVVLKPEEL 

       250        260        270        280        290        300 
RIDVMRASGP GGQGVNTTDS AVRVVHLPTG ITVTCQTTRS QIKNKELALK ILKARLYELE 

       310        320        330        340        350        360 
RKKREEELKA LRGEVRPIEW GSQIRSYVLD KNYVKDHRTG LMRHDPENVL DGDLMDLIWA 

       370 
GLEWKAGRRQ GTEEVEAE 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of the extreme thermophile Thermus thermophilus."
Henne A., Brueggemann H., Raasch C., Wiezer A., Hartsch T., Liesegang H., Johann A., Lienard T., Gohl O., Martinez-Arias R., Jacobi C., Starkuviene V., Schlenczeck S., Dencker S., Huber R., Klenk H.-P., Overbeek R., Kramer W. expand/collapse author list , Merkl R., Gottschalk G., Fritz H.-J.
Nat. Biotechnol. 22:547-553(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB27 / ATCC BAA-163 / DSM 7039.
[2]"Crystal structure of a translation termination complex formed with release factor RF2."
Korostelev A., Asahara H., Lancaster L., Laurberg M., Hirschi A., Zhu J., Trakhanov S., Scott W.G., Noller H.F.
Proc. Natl. Acad. Sci. U.S.A. 105:19684-19689(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS).
[3]"Crystal structure of the 70S ribosome bound with the Q253P mutant form of release factor RF2."
Santos N., Zhu J., Donohue J.P., Korostelev A.A., Noller H.F.
Structure 21:1258-1263(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.40 ANGSTROMS) OF 17-378.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017221 Genomic DNA. Translation: AAS82194.1.
RefSeqYP_005821.1. NC_005835.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3F1EX-ray3.00X1-378[»]
3F1GX-ray3.00X1-378[»]
4KFHX-ray3.40Y17-378[»]
4KFKX-ray3.40Y17-378[»]
ProteinModelPortalQ72GJ6.
SMRQ72GJ6. Positions 27-369.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262724.TTC1852.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS82194; AAS82194; TT_C1852.
GeneID2776319.
KEGGtth:TTC1852.
PATRIC23954173. VBITheThe54392_1851.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1186.
KOK02836.
OMAITGRYAY.
OrthoDBEOG6TN48J.
ProtClustDBCLSK445704.

Enzyme and pathway databases

BioCycTTHE262724:GCAT-1891-MONOMER.

Family and domain databases

Gene3D3.30.160.20. 1 hit.
InterProIPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004374. PrfB.
[Graphical view]
PANTHERPTHR11075:SF6. PTHR11075:SF6. 1 hit.
PfamPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsTIGR00020. prfB. 1 hit.
PROSITEPS00745. RF_PROK_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ72GJ6_THET2
AccessionPrimary (citable) accession number: Q72GJ6
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)