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Q72GJ6

- Q72GJ6_THET2

UniProt

Q72GJ6 - Q72GJ6_THET2

Protein
Submitted name:

Bacterial peptide chain release factor 2 (RF-2)

Gene

TT_C1852

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.SAAS annotation

    GO - Molecular functioni

    1. translation release factor activity, codon specific Source: InterPro

    Keywords - Biological processi

    Protein biosynthesisSAAS annotation

    Enzyme and pathway databases

    BioCyciTTHE262724:GCAT-1891-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Bacterial peptide chain release factor 2 (RF-2)Imported
    Gene namesi
    Ordered Locus Names:TT_C1852Imported
    OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)Imported
    Taxonomic identifieri262724 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000592: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation
    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi262724.TTC1852.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3F1EX-ray3.00X1-378[»]
    3F1GX-ray3.00X1-378[»]
    4KFHX-ray3.40Y17-378[»]
    4KFKX-ray3.40Y17-378[»]
    ProteinModelPortaliQ72GJ6.
    SMRiQ72GJ6. Positions 27-369.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG1186.
    KOiK02836.
    OMAiCYVDIQS.
    OrthoDBiEOG6TN48J.

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR005139. PCRF.
    IPR000352. Pep_chain_release_fac_I_II.
    IPR004374. PrfB.
    [Graphical view]
    PANTHERiPTHR11075:SF6. PTHR11075:SF6. 1 hit.
    PfamiPF03462. PCRF. 1 hit.
    PF00472. RF-1. 1 hit.
    [Graphical view]
    SMARTiSM00937. PCRF. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00020. prfB. 1 hit.
    PROSITEiPS00745. RF_PROK_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q72GJ6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLASQSAIL VKVWTWNASR NAWKASGGIF DIPQKETRLK ELERRLEDPS    50
    LWNDPEAARK VSQEAARLRR TVDTFRSLES DLQGLLELME ELPAEEREAL 100
    KPELEEAAKK LDELYHQTLL NFPHAEKNAI LTIQPGAGGT EACDWAEMLL 150
    RMYTRFAERQ GFQVEVVDLT PGPEAGIDYA QILVKGENAY GLLSPEAGVH 200
    RLVRPSPFDA SGRRHTSFAG VEVIPEVDEE VEVVLKPEEL RIDVMRASGP 250
    GGQGVNTTDS AVRVVHLPTG ITVTCQTTRS QIKNKELALK ILKARLYELE 300
    RKKREEELKA LRGEVRPIEW GSQIRSYVLD KNYVKDHRTG LMRHDPENVL 350
    DGDLMDLIWA GLEWKAGRRQ GTEEVEAE 378
    Length:378
    Mass (Da):42,734
    Last modified:July 5, 2004 - v1
    Checksum:i55B4AC9C891AEEB7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS82194.1.
    RefSeqiYP_005821.1. NC_005835.1.

    Genome annotation databases

    EnsemblBacteriaiAAS82194; AAS82194; TT_C1852.
    GeneIDi2776319.
    KEGGitth:TTC1852.
    PATRICi23954173. VBITheThe54392_1851.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS82194.1 .
    RefSeqi YP_005821.1. NC_005835.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3F1E X-ray 3.00 X 1-378 [» ]
    3F1G X-ray 3.00 X 1-378 [» ]
    4KFH X-ray 3.40 Y 17-378 [» ]
    4KFK X-ray 3.40 Y 17-378 [» ]
    ProteinModelPortali Q72GJ6.
    SMRi Q72GJ6. Positions 27-369.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262724.TTC1852.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS82194 ; AAS82194 ; TT_C1852 .
    GeneIDi 2776319.
    KEGGi tth:TTC1852.
    PATRICi 23954173. VBITheThe54392_1851.

    Phylogenomic databases

    eggNOGi COG1186.
    KOi K02836.
    OMAi CYVDIQS.
    OrthoDBi EOG6TN48J.

    Enzyme and pathway databases

    BioCyci TTHE262724:GCAT-1891-MONOMER.

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR005139. PCRF.
    IPR000352. Pep_chain_release_fac_I_II.
    IPR004374. PrfB.
    [Graphical view ]
    PANTHERi PTHR11075:SF6. PTHR11075:SF6. 1 hit.
    Pfami PF03462. PCRF. 1 hit.
    PF00472. RF-1. 1 hit.
    [Graphical view ]
    SMARTi SM00937. PCRF. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00020. prfB. 1 hit.
    PROSITEi PS00745. RF_PROK_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB27 / ATCC BAA-163 / DSM 7039Imported.
    2. Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS).
    3. "Crystal structure of the 70S ribosome bound with the Q253P mutant form of release factor RF2."
      Santos N., Zhu J., Donohue J.P., Korostelev A.A., Noller H.F.
      Structure 21:1258-1263(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.40 ANGSTROMS) OF 17-378.

    Entry informationi

    Entry nameiQ72GJ6_THET2
    AccessioniPrimary (citable) accession number: Q72GJ6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteomeImported

    External Data

    Dasty 3