Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q72GA4 (Q72GA4_THET2) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:TT_C1944 EMBL AAS82286.1
OrganismThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [Complete proteome] [HAMAP] EMBL AAS82286.1
Taxonomic identifier262724 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length361 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site441Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2571Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1421Substrate By similarity HAMAP-Rule MF_01201
Binding site3041Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue441N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q72GA4 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: C6B73A8AAE9310EB

FASTA36138,763
        10         20         30         40         50         60 
MPAGPIGLVE VEERAWVEVD LAALWANYRL LAGRAGGEVI PVLKADAYGH GALPLARFLE 

        70         80         90        100        110        120 
GKGVGRFAVA TLEEGRRLRE GGIKGEVLLL GSLHPLEAEE ALELGLVPTL STLEAAEALS 

       130        140        150        160        170        180 
QRARALGLVP RAHLKVDTGM NRVGFPWEEA ASALRAVEAL GVRVEGVYTH LATAGEDAAF 

       190        200        210        220        230        240 
VETQRRRFQE VRRALGEGYF YHLENSLGLL RHGATAGVRV GLALYGLVPG FGLRPILRIL 

       250        260        270        280        290        300 
ARPTLVKRLK AGDRVGYGGV YVARGGEWLA TLPVGYADGL PWGAVRFVKG PDGRLLEVAG 

       310        320        330        340        350        360 
RISMDQTTVL LPGPVGLEAV FEVLSADFGP TGLLAWAEAR GTLPYEVAVH LSRRLPRRYL 


E 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017221 Genomic DNA. Translation: AAS82286.1.
RefSeqYP_005913.1. NC_005835.1.

3D structure databases

ProteinModelPortalQ72GA4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262724.TTC1944.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS82286; AAS82286; TT_C1944.
GeneID2775347.
KEGGtth:TTC1944.
PATRIC23954357. VBITheThe54392_1938.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
KOK01775.
OMACIDEALT.
OrthoDBEOG6PP9NJ.
ProtClustDBCLSK738977.

Enzyme and pathway databases

BioCycTTHE262724:GCAT-1988-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ72GA4_THET2
AccessionPrimary (citable) accession number: Q72GA4
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)