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Protein

Glycogen synthase

Gene

glgA

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-2024-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:TT_C1980
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000000592 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 437437Glycogen synthasePRO_0000230267Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi262724.TTC1980.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
KOiK00703.
OMAiPAYDEAM.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q72G68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVLHVAPEA YPLAKVGGLA DVVGALPKAL GPLGVEAHVL LPWHGGLEAR
60 70 80 90 100
RVGEVAFAFF GREERAPLGE RVEGGVRFLL LGVEGFGRER VYGYPDDAER
110 120 130 140 150
YLRFALAAKE VARGYDLVHA HDWTAALLAL YAPTVYTIHN LAHQGLVDPG
160 170 180 190 200
LFFSWTGLPW SLFHMEALEF YGRVNLMKGG IVFARRVTTV SPSYAEEIQT
210 220 230 240 250
PEFGMGLDGV LRRHAGKLRG ILNGLDTEVF DPGKDPYLPA PYTREDPSGK
260 270 280 290 300
ARAKEAFRER TGLRPPVLAY VGRLDYQKGL DLVLKALPRL LEMGFRLYVQ
310 320 330 340 350
GVGDGGLQEA FLRAEEENPE GVRFLPAYDE AMARLAYAGA EAVLVPSRFE
360 370 380 390 400
PCGLVQMIAS RYGTPPVARA VGGLKDTVED GRAGVLFETY HPEGLLYGVL
410 420 430
RLFRLGAEEM GLRAMEKDFS WEGPARAYRE VYREALG
Length:437
Mass (Da):48,174
Last modified:April 3, 2006 - v2
Checksum:iB2C52E0E6745B843
GO

Sequence cautioni

The sequence AAS82322.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017221 Genomic DNA. Translation: AAS82322.1. Different initiation.
RefSeqiYP_005949.1. NC_005835.1.

Genome annotation databases

EnsemblBacteriaiAAS82322; AAS82322; TT_C1980.
KEGGitth:TTC1980.
PATRICi23954427. VBITheThe54392_1973.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017221 Genomic DNA. Translation: AAS82322.1. Different initiation.
RefSeqiYP_005949.1. NC_005835.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi262724.TTC1980.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS82322; AAS82322; TT_C1980.
KEGGitth:TTC1980.
PATRICi23954427. VBITheThe54392_1973.

Phylogenomic databases

eggNOGiCOG0297.
KOiK00703.
OMAiPAYDEAM.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciTTHE262724:GCAT-2024-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB27 / ATCC BAA-163 / DSM 7039.

Entry informationi

Entry nameiGLGA_THET2
AccessioniPrimary (citable) accession number: Q72G68
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2006
Last sequence update: April 3, 2006
Last modified: March 31, 2015
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.