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Protein

Cytochrome c-type protein

Gene

DVU_0624

Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei43 – 431Heme 1 (covalent)Combined sources
Binding sitei46 – 461Heme 1 (covalent)Combined sources
Metal bindingi49 – 491Iron (heme 1 axial ligand)Combined sources
Metal bindingi61 – 611Iron (heme 3 axial ligand); via tele nitrogenCombined sources
Binding sitei66 – 661Heme 2 (covalent)Combined sources
Binding sitei69 – 691Heme 2 (covalent)Combined sources
Metal bindingi70 – 701Iron (heme 2 axial ligand); via tele nitrogenCombined sources
Metal bindingi89 – 891Iron (heme 1 axial ligand)Combined sources
Binding sitei116 – 1161Heme 3 (covalent)Combined sources
Metal bindingi120 – 1201Iron (heme 3 axial ligand); via tele nitrogenCombined sources
Binding sitei136 – 1361Heme 4 (covalent)Combined sources
Metal bindingi140 – 1401Iron (heme 4 axial ligand); via tele nitrogenCombined sources
Metal bindingi145 – 1451Iron (heme 2 axial ligand); via tele nitrogenCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transportUniRule annotation, Transport

Keywords - Ligandi

HemeUniRule annotationCombined sources, Iron, Metal-binding

Enzyme and pathway databases

BioCyciDVUL882:GJIL-645-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c-type proteinUniRule annotation
Gene namesi
Ordered Locus Names:DVU_0624Imported
OrganismiDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)Imported
Taxonomic identifieri882 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000002194 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Post-translational modificationi

Binds 4 heme groups per subunit.UniRule annotation

Proteomic databases

PaxDbiQ72EF4.

Interactioni

Protein-protein interaction databases

STRINGi882.DVU0624.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2J7AX-ray2.30C/F/I/L/O/R1-159[»]
2VR0X-ray2.80C/F1-159[»]
ProteinModelPortaliQ72EF4.
SMRiQ72EF4. Positions 14-159.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ72EF4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini38 – 145108Cytochrome cInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4108W6G. Bacteria.
COG3005. LUCA.
KOiK15876.
OMAiCASCHIM.
OrthoDBiEOG6Q5NXQ.
PhylomeDBiQ72EF4.

Family and domain databases

InterProiIPR011031. Multihaem_cyt.
IPR024717. NapC/NirT/NrfH.
IPR005126. NapC/NirT_cyt_c_N.
[Graphical view]
PfamiPF03264. Cytochrom_NNT. 1 hit.
[Graphical view]
PIRSFiPIRSF000013. 4_hem_cytochrm_NapC. 1 hit.
SUPFAMiSSF48695. SSF48695. 1 hit.
PROSITEiPS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q72EF4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEKSRNGP ARLKLVLGGA TLGVVALATV AFGMKYTDQR PFCTSCHIMN
60 70 80 90 100
PVGVTHKLSG HANISCNDCH APHNLLAKLP FKAIAGARDV YMNTLGHPGD
110 120 130 140 150
LILAGMETKE VVNANCKACH TMTNVEVASM EAKKYCTDCH RNVQHMRMKP

ISTREVADE
Length:159
Mass (Da):17,263
Last modified:July 5, 2004 - v1
Checksum:i0D44379C53D61416
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017285 Genomic DNA. Translation: AAS95105.1.
RefSeqiWP_010937927.1. NC_002937.3.
YP_009846.1. NC_002937.3.

Genome annotation databases

EnsemblBacteriaiAAS95105; AAS95105; DVU_0624.
GeneIDi2796148.
KEGGidvu:DVU0624.
PATRICi32061182. VBIDesVul119526_0582.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017285 Genomic DNA. Translation: AAS95105.1.
RefSeqiWP_010937927.1. NC_002937.3.
YP_009846.1. NC_002937.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2J7AX-ray2.30C/F/I/L/O/R1-159[»]
2VR0X-ray2.80C/F1-159[»]
ProteinModelPortaliQ72EF4.
SMRiQ72EF4. Positions 14-159.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi882.DVU0624.

Proteomic databases

PaxDbiQ72EF4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS95105; AAS95105; DVU_0624.
GeneIDi2796148.
KEGGidvu:DVU0624.
PATRICi32061182. VBIDesVul119526_0582.

Phylogenomic databases

eggNOGiENOG4108W6G. Bacteria.
COG3005. LUCA.
KOiK15876.
OMAiCASCHIM.
OrthoDBiEOG6Q5NXQ.
PhylomeDBiQ72EF4.

Enzyme and pathway databases

BioCyciDVUL882:GJIL-645-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ72EF4.

Family and domain databases

InterProiIPR011031. Multihaem_cyt.
IPR024717. NapC/NirT/NrfH.
IPR005126. NapC/NirT_cyt_c_N.
[Graphical view]
PfamiPF03264. Cytochrom_NNT. 1 hit.
[Graphical view]
PIRSFiPIRSF000013. 4_hem_cytochrm_NapC. 1 hit.
SUPFAMiSSF48695. SSF48695. 1 hit.
PROSITEiPS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hildenborough / ATCC 29579 / NCIMB 8303Imported.
  2. "X-ray structure of the membrane-bound cytochrome c quinol dehydrogenase NrfH reveals novel haem coordination."
    Rodrigues M.L., Oliveira T.F., Pereira I.A., Archer M.
    EMBO J. 25:5951-5960(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) IN COMPLEX WITH HEME.
  3. "Quinol oxidation by c-type cytochromes: structural characterization of the menaquinol binding site of NrfHA."
    Rodrigues M.L., Scott K.A., Sansom M.S., Pereira I.A., Archer M.
    J. Mol. Biol. 381:341-350(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) IN COMPLEX WITH HEME.

Entry informationi

Entry nameiQ72EF4_DESVH
AccessioniPrimary (citable) accession number: Q72EF4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 16, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.