Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q72CN5 (SYR_DESVH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:DVU_1248
OrganismDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303) [Reference proteome] [HAMAP]
Taxonomic identifier882 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 551551Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242016

Regions

Motif125 – 13511"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q72CN5 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 1F2085596C6C67C5

FASTA55160,510
        10         20         30         40         50         60 
MRAKKQLLAA LQDIVKDMGL AWPEKATIDT PKATGFGDLA ANIALVLAKQ AGQNPRELAT 

        70         80         90        100        110        120 
RIADALRNRD ADITAIDIAG PGFLNVTYSQ DFWRETILRA QEAGSAFGSS DTGAGRKVQV 

       130        140        150        160        170        180 
EYVSANPTGP LHIGHGRGAA VGDSLARIMR FAGYDVSTEY YINDAGRQMR LLGLSVWVRA 

       190        200        210        220        230        240 
KELAGRPVTL PEDFYRGDYI KDIARELMEK EPGLLDLDDA AGEDRCFAYA MSSILDGIKQ 

       250        260        270        280        290        300 
DLADFRVEHQ VWFSERSLVE GGAVEKTFNR LKEAGLAFEQ DGALWFRTTD FGDDKDRVLR 

       310        320        330        340        350        360 
KSDGTLTYFS SDIAYHDNKY DRGFDLVVDI WGADHHGYIP RMRAAVAALG RKPEAFDVVL 

       370        380        390        400        410        420 
IQLVNLLRGG ELVAMSTRAG QFETLADVVK ETGADAARFM FLSRKSDSPL DFDLELVKQR 

       430        440        450        460        470        480 
TMDNPVYYVQ YAHARVCSVL RKAAERGIEM PAQLDGASLA PLSGDDEMEL LRLLDRFEET 

       490        500        510        520        530        540 
VAGAATALAP HHISHYLMEV AGALHSYYAR QPILNATEQD VIVPRLALLR AVGCVLANGL 

       550 
SLLGVSAPES M 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017285 Genomic DNA. Translation: AAS95726.1.
RefSeqYP_010467.1. NC_002937.3.

3D structure databases

ProteinModelPortalQ72CN5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING882.DVU1248.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS95726; AAS95726; DVU_1248.
GeneID2795029.
KEGGdvu:DVU1248.
PATRIC32062366. VBIDesVul119526_1167.

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycDVUL882:GJIL-1274-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_DESVH
AccessionPrimary (citable) accession number: Q72CN5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries