Q72CN3 (RSMG_DESVH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase G
EC=2.1.1.170

Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase

Gene names

Name:	rsmG
Ordered Locus Names:	DVU_1250

Organism

Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)

Taxonomic identifier

882 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the N7 position of guanosine in position 527 of 16S rRNA By similarity. HAMAP MF_00074
Catalytic activity	S-adenosyl-L-methionine + guanosine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanosine(527) in 16S rRNA. HAMAP MF_00074
Subcellular location	Cytoplasm Potential HAMAP MF_00074.
Sequence similarities	Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	Ribosomal RNA small subunit methyltransferase G HAMAP MF_00074		PRO_0000342913

Sequences

	Sequence		Length	Mass (Da)
	Q72CN3 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 18A5A2E43F9E8E10	FASTA	218	24,221
	10 20 30 40 50 60 MAGRVEVSRK ELTKFCREAG FEPSPGMLEA IAGYLELLLH WNRSMNLVGT RTWQDTFHTL 70 80 90 100 110 120 VVDSLHLAAF LDTLPLPPEP EVWDLGAGAG LPGIPLRAAW QRGNYTMVEA REKRAMFLRM 130 140 150 160 170 180 ALARHPLPGT NVFQGRAEAF MPSRPPADLV VSRAFMPWRE LLDFVSGHLA PGGQVVFLSL 190 200 210 DPVPASLPEG WAVEAESLYG TRCGGRYFWS LRPIIVPN

References

[1]

"The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough." Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T., Kolonay J.F., Eisen J.A., Ward N.L., Methe B.A., Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Fouts D.E. , Haft D.H., Selengut J., Peterson J.D., Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M., Tran K., Khouri H.M., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D., Voordouw G., Fraser C.M. Nat. Biotechnol. 22:554-559(2004) [PubMed: 15077118] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hildenborough / ATCC 29579 / NCIMB 8303.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017285 Genomic DNA. Translation: AAS95728.1.
RefSeq	YP_010469.1. NC_002937.3.
3D structure databases
HSSP	HSSP built from PDB template 1JSX based on UniProtKB P0A6U5.
ProteinModelPortal	Q72CN3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q72CN3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2795031.
GenomeReviews	Gene locus DVU_1250 in contig AE017285_GR.
KEGG	dvu:DVU1250.
PATRIC	32062370. VBIDesVul119526_1169.
TIGR	DVU_1250.
Phylogenomic databases
eggNOG	NOG114214.
HOGENOM	HBG458177.
OMA	GGQGWIV.
PhylomeDB	Q72CN3.
ProtClustDB	CLSK705129.
Enzyme and pathway databases
BioCyc	DVUL882:DVU_1250-MONOMER.
Family and domain databases
HAMAP	MF_00074. 16SrRNA_methyltr_G. [Tree]
InterPro	IPR003682. rRNA_ssu_MeTfrase_G. [Graphical view]
KO	K03501.
Pfam	PF02527. GidB. 1 hit. [Graphical view]
PIRSF	PIRSF003078. GidB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RSMG_DESVH

Accession

Primary (citable) accession number: Q72CN3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program