Q72CG8 (RL5_DESVH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L5

Gene names

Name:	rplE
Ordered Locus Names:	DVU_1315

Organism

Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303) [Reference proteome] [HAMAP]

Taxonomic identifier

882 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio › Desulfovibrio vulgaris

Protein attributes

Sequence length	179 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs By similarity. HAMAP-Rule MF_01333
Subunit structure	Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome By similarity.
Sequence similarities	Belongs to the ribosomal protein L5P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 179	179	50S ribosomal protein L5 HAMAP-Rule MF_01333		PRO_0000124924

Sequences

	Sequence		Length	Mass (Da)
	Q72CG8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: EA7488423B1AF0EC	FASTA	179	20,212
	10 20 30 40 50 60 MTRLENIYRE KVVPVLQKEF NYDSSMQVPG IVKVSLNIGL GAASQNNKLM EEALKELTVI 70 80 90 100 110 120 AGQKAVVTRA KKSIASFKLR EGMPIGCRVT LRKERMWDFL DKLINFALPR VRDFRGVPDR 130 140 150 160 170 GFDGRGNFTL GIKEHAIFPE MEADRVENPK GMNITIVTTA TTDKEGKLLL DQLGMPFRK

References

[1]

"The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough." Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T., Kolonay J.F., Eisen J.A., Ward N.L., Methe B.A., Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Fouts D.E. , Haft D.H., Selengut J., Peterson J.D., Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M., Tran K., Khouri H.M., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D., Voordouw G., Fraser C.M. Nat. Biotechnol. 22:554-559(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hildenborough / ATCC 29579 / NCIMB 8303.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017285 Genomic DNA. Translation: AAS95793.1.
RefSeq	YP_010534.1. NC_002937.3.
3D structure databases
ProteinModelPortal	Q72CG8.
SMR	Q72CG8. Positions 1-179.
ModBase	Search...
Protein-protein interaction databases
STRING	882.DVU1315.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAS95793; AAS95793; DVU_1315.
GeneID	2794382.
KEGG	dvu:DVU1315.
PATRIC	32062488. VBIDesVul119526_1227.
Phylogenomic databases
eggNOG	COG0094.
KO	K02931.
OMA	EQVMFHE.
ProtClustDB	PRK00010.
Enzyme and pathway databases
BioCyc	DVUL882:GJIL-1343-MONOMER.
Family and domain databases
Gene3D	3.30.1440.10. 1 hit.
HAMAP	MF_01333_B. Ribosomal_L5_B.
InterPro	IPR002132. Ribosomal_L5. IPR020930. Ribosomal_L5_bac-type. IPR020929. Ribosomal_L5_CS. IPR022803. Ribosomal_L5_domain. [Graphical view]
PANTHER	PTHR11994. PTHR11994. 1 hit.
Pfam	PF00281. Ribosomal_L5. 1 hit. PF00673. Ribosomal_L5_C. 1 hit. [Graphical view]
PIRSF	PIRSF002161. Ribosomal_L5. 1 hit.
SUPFAM	SSF55282. Ribosomal_L5. 1 hit.
PROSITE	PS00358. RIBOSOMAL_L5. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL5_DESVH

Accession

Primary (citable) accession number: Q72CG8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program