Reviewed, UniProtKB/Swiss-Prot Q72CF1 (SELD_DESVH)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase
    Selenium donor protein

Gene names

Name:	selD
Ordered Locus Names:	DVU_1332

Organism

Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303) [Complete proteome] [HAMAP]

Taxonomic identifier

882 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity.
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.

Ontologies

Keywords
Coding sequence diversity	Selenocysteine
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 351	351	Selenide, water dikinase HAMAP MF_00625		PRO_0000127619
Regions
	Nucleotide binding	230 – 236	7	ATP Potential
Sites
	Active site	15	1	Potential
	Site	18	1	Important for catalytic activity By similarity
Amino acid modifications
	Non-standard residue	15	1	Selenocysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	Q72CF1-1 [UniParc]. Last modified February 26, 2008. Version 2. Checksum: A0D8EA131E368427	FASTA	351	36,973
	10 20 30 40 50 60 MTVDRLTSRS RAAGUAAKIA PGDLERILAT LPRDPREGER VVVGTRDNED AAIVRVPGGK 70 80 90 100 110 120 AIVQTLDFFT PIVDDPYLFG QIAAANALSD VYAMGGEPWC ALNIVCFPVK ELPEDILADI 130 140 150 160 170 180 LRGGADKVRE AGAVLVGGHS IEDESIKYGL SVTGIIDPDC YATNTGLRPG DVLLLTKPLG 190 200 210 220 230 240 SGVLATAVKA GWDGFEAHEQ ELGRWGAMLN RAGGRVIREL GLAAATDVTG FGLGGHLLEM 250 260 270 280 290 300 ANASNMSVHV DVSTLPLMPA VLDLVATGLL PAGSHANRHF CSGNVSVHPE VDSLLVDIVF 310 320 330 340 350 DAQTSGGLIL AVPPHLVDDA CSILRAEDAP FWRIGHVEEM GEGVPRLVLQ P

References

[1]

"The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough." Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T., Kolonay J.F., Eisen J.A., Ward N.L., Methe B.A., Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Fouts D.E. , Haft D.H., Selengut J., Peterson J.D., Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M., Tran K., Khouri H.M., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D., Voordouw G., Fraser C.M. Nat. Biotechnol. 22:554-559(2004) [PubMed: 15077118] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017285 Genomic DNA. Translation: AAS95810.1.
RefSeq	YP_010551.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q72CF1.
Genome annotation databases
GeneID	2794579.
GenomeReviews	Gene locus DVU_1332 in contig AE017285_GR.
KEGG	dvu:DVU1332.
TIGR	DVU_1332.
Phylogenomic databases
HOGENOM	Q72CF1.
OMA	GGHTVED.
Enzyme and pathway databases
BioCyc	DVUL882:DVU_1332-MON.
Family and domain databases
HAMAP	MF_00625. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_DESVH

Accession

Primary (citable) accession number: Q72CF1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	February 26, 2008
Last modified:	November 3, 2009
This is version 32 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)