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Q72C44 (RNC_DESVH) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:DVU_1440
OrganismDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303) [Reference proteome] [HAMAP]
Taxonomic identifier882 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio

Protein attributes

Sequence length253 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 253253Ribonuclease 3 HAMAP-Rule MF_00104
PRO_0000228526

Regions

Domain29 – 157129RNase III
Domain184 – 25370DRBM

Sites

Active site741 Potential
Active site1461 By similarity
Metal binding701Magnesium By similarity
Metal binding1431Magnesium By similarity
Metal binding1461Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q72C44 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 23BC28925D562B63

FASTA25328,341
        10         20         30         40         50         60 
MWARTAAWVF GLPETLREIC YRRDNVKPVD ELQKTIGHRF GDMELLLTAM THSSWANEQA 

        70         80         90        100        110        120 
VPVEHNERLE FLGDAVLELC VSEELFRRFP SAREGDLTRM RSRLVSKPSL EGVARELRLD 

       130        140        150        160        170        180 
MSLRLGKGEE SQGGRERGSL LSDALEAMLG AVFLDAGYIA AKGVVMRILG PHFPEALVPV 

       190        200        210        220        230        240 
RTKDYKSQLQ ELTQKLFRDR PVYTLLGSSG PEHDKQFDVR VVLPDGTVFE ATGPSMKRAE 

       250 
QMAAARAVAT LDK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017285 Genomic DNA. Translation: AAS95918.1.
RefSeqYP_010659.1. NC_002937.3.

3D structure databases

ProteinModelPortalQ72C44.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING882.DVU1440.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS95918; AAS95918; DVU_1440.
GeneID2795166.
KEGGdvu:DVU1440.
PATRIC32062712. VBIDesVul119526_1339.

Phylogenomic databases

eggNOGCOG0571.
KOK03685.
OMAYGFQEAR.
OrthoDBEOG6T1WVS.
PhylomeDBQ72C44.

Enzyme and pathway databases

BioCycDVUL882:GJIL-1469-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_DESVH
AccessionPrimary (citable) accession number: Q72C44
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families