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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathway: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei317 – 3171NucleophileUniRule annotation
Active sitei370 – 3701Proton donorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciDVUL882:GJIL-2295-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:DVU_2243
OrganismiDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)
Taxonomic identifieri882 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
ProteomesiUP000002194 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6406401,4-alpha-glucan branching enzyme GlgBPRO_0000188701Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi882.DVU2243.

Structurei

3D structure databases

ProteinModelPortaliQ729V5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0296.
KOiK00700.
OMAiFLPITEY.
OrthoDBiEOG6JX7GT.
PhylomeDBiQ729V5.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

Q729V5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIPCSRPLF IEPFDLYLFG MGRHRHLYRI LGAHPAVQDG EAGYRFAVWA
60 70 80 90 100
PNARSVHLSG DCNGWRHEGC PLFPVGVSGV WAAFVPGVRR GSLYKFVVRG
110 120 130 140 150
ADGRQEQKAD PFALWAEMRP GVASVAWDID NHAWGDGAWM AERARQGLPL
160 170 180 190 200
ERPVSIYEVH LGSWRRRHGD GHPFLTYDEL GDQLIPYATG LGFTHLELLP
210 220 230 240 250
VAEHPLDQSW GYQTGHYYAP TSRFGSPEGF KRFVDRCHQA GLGVILDWVP
260 270 280 290 300
AHFPRDAWSL GRFDGTALYE HLDPRLGEHP DWGTYIFNYG RNEVRNFLTA
310 320 330 340 350
NALYWLREFH IDGLRMDAVA SMLYLDYSRE AGQWLPNRHG GRENLDAVDF
360 370 380 390 400
LREVNTVIHA EFPGAMTLAE ESTAWPGVSR PVYTGGLGFS FKWNMGWMHD
410 420 430 440 450
TLGYLAEDPI HRAYHHGSLT FSMLYAFSEN FVLPLSHDEV VHGKGALLSK
460 470 480 490 500
MPGDMWQQQA NLRLLYAYQW AHPGKKLLFM GGEFGQWNEW DESRELDWCL
510 520 530 540 550
YRFPAHEGIA RLVGDLNRLL RSEPAMHRRD HDWSGFRWVD FADYGSSVIS
560 570 580 590 600
FLRLAAGERP LLWIFNFTPV VRRFYRVPCP RGGTWRELCN TDSAYYGGSD
610 620 630 640
VGNAGAVMAR EDHWGGGHFI ELTLPPLAAM CFAPVTGQGT
Length:640
Mass (Da):72,703
Last modified:July 5, 2004 - v1
Checksum:i23AA58BDA13428AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017285 Genomic DNA. Translation: AAS96716.1.
RefSeqiWP_010939518.1. NC_002937.3.
YP_011456.1. NC_002937.3.

Genome annotation databases

EnsemblBacteriaiAAS96716; AAS96716; DVU_2243.
GeneIDi2795395.
KEGGidvu:DVU2243.
PATRICi32064144. VBIDesVul119526_2038.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017285 Genomic DNA. Translation: AAS96716.1.
RefSeqiWP_010939518.1. NC_002937.3.
YP_011456.1. NC_002937.3.

3D structure databases

ProteinModelPortaliQ729V5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi882.DVU2243.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS96716; AAS96716; DVU_2243.
GeneIDi2795395.
KEGGidvu:DVU2243.
PATRICi32064144. VBIDesVul119526_2038.

Phylogenomic databases

eggNOGiCOG0296.
KOiK00700.
OMAiFLPITEY.
OrthoDBiEOG6JX7GT.
PhylomeDBiQ729V5.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciDVUL882:GJIL-2295-MONOMER.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hildenborough / ATCC 29579 / NCIMB 8303.

Entry informationi

Entry nameiGLGB_DESVH
AccessioniPrimary (citable) accession number: Q729V5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: July 5, 2004
Last modified: April 29, 2015
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.