Reviewed, UniProtKB/Swiss-Prot Q729V4 (GLGA_DESVH)

Names and origin

Protein names

Recommended name:
    Glycogen synthase
    EC=2.4.1.21
Alternative name(s):
    Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	DVU_2244

Organism

Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303) [Complete proteome] [HAMAP]

Taxonomic identifier

882 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	489 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 489	489	Glycogen synthase HAMAP MF_00484		PRO_0000188610
Sites
	Binding site	17	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q729V4-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: A91C7364F29C7BF3	FASTA	489	54,678
	10 20 30 40 50 60 MQRQVVFATS EMYPFSKSGG LGDVLGALPL ALHRMGVPTA VVTPFYGRLR TADYPIRLTV 70 80 90 100 110 120 SDCHVGYPWA PITCDVFEAD YHGMPVYFIH RGEYFDRRYY YNDHKGDYFD NCERFVFFCR 130 140 150 160 170 180 ALLALMRRLG QPPAVLHAHD WQTALVPAFL YFLRQTDPFW QDTRSVLTIH NLAFQGRFAS 190 200 210 220 230 240 RLFETSGLPP QAWSVDGAEF WGDFNLLKAG IAYADKVTTV SPSYAREILG PAYGSGLDGI 250 260 270 280 290 300 LRKRAHALHG ILNGADYDIW SPGNDRFLPC RYTPTDLAGK AQCKRALIEE LGLDPHLARR 310 320 330 340 350 360 PILGFIGRLR GQKGIDLLLD ILPRLMESDV GVIILGEGNL THEARALELM EAYRGRVCTI 370 380 390 400 410 420 VSYTEDLAHR IQAGSDIFLM PSRYEPCGLT QMYALRYGTP PVATAVGGLR DTIVPWPSPE 430 440 450 460 470 480 STGFTFGRCE SAAFLRAILD AVHLWTTAPG DWQGMVRRAM AQAFTWERAG RAYLDLYAQL GVSPGEEGA

References

[1]

"The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough." Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T., Kolonay J.F., Eisen J.A., Ward N.L., Methe B.A., Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Fouts D.E. , Haft D.H., Selengut J., Peterson J.D., Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M., Tran K., Khouri H.M., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D., Voordouw G., Fraser C.M. Nat. Biotechnol. 22:554-559(2004) [PubMed: 15077118] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017285 Genomic DNA. Translation: AAS96717.1.
RefSeq	YP_011457.1.
3D structure databases
SMR	Q729V4. Positions 4-480.
ModBase	Search...
Protein-protein interaction databases
STRING	Q729V4.
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Genome annotation databases
GeneID	2795396.
GenomeReviews	Gene locus DVU_2244 in contig AE017285_GR.
KEGG	dvu:DVU2244.
NMPDR	fig|882.1.peg.2232.
TIGR	DVU_2244.
Phylogenomic databases
eggNOG	COG0297.
HOGENOM	HBG596384.
OMA	LPGYPAV.
PhylomeDB	Q729V4.
Enzyme and pathway databases
BioCyc	DVUL882:DVU_2244-MONOMER.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR011835. GlgA. IPR001296. Glyco_trans_1. IPR013534. Starch_synth_cat_dom. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_DESVH

Accession

Primary (citable) accession number: Q729V4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	July 5, 2004
Last modified:	February 9, 2010
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)