ID   Q728L8_DESVH            Unreviewed;       626 AA.
AC   Q728L8;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 108.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAS97057.1};
GN   OrderedLocusNames=DVU_2585 {ECO:0000313|EMBL:AAS97057.1};
OS   Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM
OS   B-1760 / Hildenborough).
OC   Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC   Desulfovibrionaceae; Nitratidesulfovibrio.
OX   NCBI_TaxID=882 {ECO:0000313|EMBL:AAS97057.1, ECO:0000313|Proteomes:UP000002194};
RN   [1] {ECO:0000313|EMBL:AAS97057.1, ECO:0000313|Proteomes:UP000002194}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough
RC   {ECO:0000313|Proteomes:UP000002194};
RX   PubMed=15077118; DOI=10.1038/nbt959;
RA   Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T.,
RA   Kolonay J.F., Eisen J.A., Ward N., Methe B., Brinkac L.M., Daugherty S.C.,
RA   Deboy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C.,
RA   Sullivan S.A., Fouts D., Haft D.H., Selengut J., Peterson J.D.,
RA   Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M.,
RA   Tran K., Khouri H., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D.,
RA   Voordouw G., Fraser C.M.;
RT   "The genome sequence of the anaerobic, sulfate-reducing bacterium
RT   Desulfovibrio vulgaris Hildenborough.";
RL   Nat. Biotechnol. 22:554-559(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE017285; AAS97057.1; -; Genomic_DNA.
DR   RefSeq; WP_010939855.1; NC_002937.3.
DR   RefSeq; YP_011797.1; NC_002937.3.
DR   AlphaFoldDB; Q728L8; -.
DR   SMR; Q728L8; -.
DR   STRING; 882.DVU_2585; -.
DR   PaxDb; 882-DVU_2585; -.
DR   EnsemblBacteria; AAS97057; AAS97057; DVU_2585.
DR   KEGG; dvu:DVU_2585; -.
DR   PATRIC; fig|882.5.peg.2342; -.
DR   eggNOG; COG0840; Bacteria.
DR   eggNOG; COG4564; Bacteria.
DR   HOGENOM; CLU_000445_107_19_7; -.
DR   OrthoDB; 9791237at2; -.
DR   PhylomeDB; Q728L8; -.
DR   Proteomes; UP000002194; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004010; Double_Cache_2.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR033480; sCache_2.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF08269; dCache_2; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM01049; Cache_2; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002194};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        233..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          253..305
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          353..589
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          290..341
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          424..451
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   626 AA;  66955 MW;  711B409E122FC582 CRC64;
     MQHRPALDLA PEAASRGRFQ PGVGARLLLL VGGIVALFVL TIFVGILPTV EQRLLAARGD
     ALRNMIQNVD KLLQEYDARV QKGEFTREEG MKRAALRIGS MRYGNNDYFW INDTGTPYPT
     MIMHPVATQL VGKVLDSPNY QRATGWRTAP GEDFNAYPAG KNLFQAFVDV VQRNGSGLVS
     YAWPKPLPGG GASSELYNKE SYVTLFRPWG WIVGTGVYVD DIERDVTALR LRVLTLSGGI
     LLLVCAFGWI LIRSIRRPLD SLASYARKVA DGDLGAHVSG SFIAEFGELK HSLETMVEAL
     RTKIAEAQEK TDEASIMARR AEEQTHAAEA AREEAERARS EGMVDAANQL EAIVRDVGRA
     ASALTGLVRV AAEGAGRQRA RVGETSVSME EMNATVLDVA RNAGQAATTS EAARAKAQQG
     AGGVEQVVAS VAQVEREAAS LRESMGALSK RADAIGQIMS VISDIADQTN LLALNAAIEA
     ARAGEAGRGF AVVADEVRKL AEKTMNATKE VDSAIRGIQQ GTGESSRNVD AASRAVGEAA
     EHARAAGESL GEIVRLAEQV SDQIRSIATA SEEQSSSSES IAHALDGVAG VADDTSRAMD
     DAMHSLRDLE GGTTNLTRLI ERLKKS
//