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Q726S7 (PTA_DESVH) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:DVU_3029
OrganismDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303) [Reference proteome] [HAMAP]
Taxonomic identifier882 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio

Protein attributes

Sequence length704 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subunit structure

Homohexamer By similarity.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 704704Phosphate acetyltransferase
PRO_0000405547

Regions

Region380 – 704325Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
Q726S7 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: C0459B13A61D8DAA

FASTA70476,830
        10         20         30         40         50         60 
MSNNLYITAT ESKSGKSAVV LGMMQLLLRD VRKVAFFRPI INQASTDVRD HDINLILRHF 

        70         80         90        100        110        120 
GLDIAYEDTY AYSLQDAREL INNGQHATLL DNILKKYKKL EDAYDFVLCE GTDFLGKDAA 

       130        140        150        160        170        180 
FEFELNADIA ANLGCPVMVV ANGQQKAARE LIASTQLTID LLDEKGLDVV TAVINRATVT 

       190        200        210        220        230        240 
EAEREEIIKS LECKVNCSNP LAVYVLPEES TLGKPTMNDV KKWLGAQVLY GHGRLDTLVD 

       250        260        270        280        290        300 
DYIIAAMQIG NFLDYVSQGC LVITPGDRSD IILSSLASRL STAYPDISGL LLTGGLEPAA 

       310        320        330        340        350        360 
NVHRLIEGWT GVPIPILSVK DHTYKTIQTL NELYGKIEPD NDRKINTALA LFERHIDSSE 

       370        380        390        400        410        420 
LGSRLINRKS SRITPKMFEF NLIEKAKRNR MRIVLPEGAE ERILRAADIL VRREVADIIL 

       430        440        450        460        470        480 
LGDANTVGSR IGDLGLDMDG VQIVQPNLSP KFDEYVAAYH ECRKKKGISM EQARDMMNDP 

       490        500        510        520        530        540 
TYFGTMMVHK GDADGMVSGA INTTAHTIRP AFEFIKTKPG VSIVSSVFLM CLKDRVLVFG 

       550        560        570        580        590        600 
DCAVNPNPTA EQLAEIAISA SHTARIFGVD PRVAMLSYST GSSGKGADVE KVIEATRIAK 

       610        620        630        640        650        660 
ERAPELLLEG PLQYDAAIDM DVARTKLPGS TVAGQATVFI FPDLNTGNNT YKAVQRAAGA 

       670        680        690        700 
VAIGPVLQGL NKPVNDLSRG CTVADIVNTV AITAIQAQAE KGLI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017285 Genomic DNA. Translation: AAS97500.1.
RefSeqYP_012240.1. NC_002937.3.

3D structure databases

ProteinModelPortalQ726S7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING882.DVU3029.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS97500; AAS97500; DVU_3029.
GeneID2796446.
KEGGdvu:DVU3029.
PATRIC32065612. VBIDesVul119526_2747.

Phylogenomic databases

eggNOGCOG0280.
KOK13788.
OMAATIRPAF.
OrthoDBEOG6BKJ5W.
PhylomeDBQ726S7.

Enzyme and pathway databases

BioCycDVUL882:GJIL-3105-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

Gene3D3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_DESVH
AccessionPrimary (citable) accession number: Q726S7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways