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Protein

Protein Vpr

Gene

vpr

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ActivatorSAAS annotation

Keywords - Biological processi

Cell cycleSAAS annotation, Host-virus interactionSAAS annotation, Transcription, Transcription regulationSAAS annotation, Viral penetration into host nucleusSAAS annotation, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Protein VprSAAS annotation
Gene namesi
Name:vprImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host nucleus SAAS annotation
  • Virion SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host nucleusSAAS annotation, VirionSAAS annotation

Pathology & Biotechi

Keywords - Diseasei

AIDSSAAS annotation

Interactioni

Protein-protein interaction databases

DIPiDIP-60886N.

Structurei

3D structure databases

ProteinModelPortaliQ72500.
SMRiQ72500. Positions 1-96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR000012. RetroV_VpR/X.
[Graphical view]
PfamiPF00522. VPR. 1 hit.
[Graphical view]
PRINTSiPR00444. HIVVPRVPX.

Sequencei

Sequence statusi: Complete.

Q72500-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQAPEDQGP QREPYNEWTL ELLEELKSEA VRHFPRIWLH NLGRHIYETY
60 70 80 90
GDTWAGVEAI IRILQQLPFI HFRIGCRHSR IGVTRQRRAR NGASRS
Length:96
Mass (Da):11,391
Last modified:November 1, 1996 - v1
Checksum:i9BBC53572BF360E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U26942 Genomic DNA. Translation: AAB60574.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U26942 Genomic DNA. Translation: AAB60574.1.

3D structure databases

ProteinModelPortaliQ72500.
SMRiQ72500. Positions 1-96.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60886N.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000012. RetroV_VpR/X.
[Graphical view]
PfamiPF00522. VPR. 1 hit.
[Graphical view]
PRINTSiPR00444. HIVVPRVPX.
ProtoNetiSearch...

Publicationsi

  1. "Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone."
    Adachi A., Gendelman H.E., Koenig S., Folks T., Willey R., Rabson A., Martin M.A.
    J. Virol. 59:284-291(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NL4-3Imported.
  2. "Recovery of virtually full-length HIV-1 provirus of diverse subtypes from primary virus cultures using the polymerase chain reaction."
    Salminen M.O., Koch C., Sanders-Buell E., Ehrenberg P.K., Michael N.L., Carr J.K., Burke D.S., McCutchan F.E.
    Virology 213:80-86(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NL4-3Imported.
  3. Salminen M.S.
    Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NL4-3Imported.

Entry informationi

Entry nameiQ72500_9HIV1
AccessioniPrimary (citable) accession number: Q72500
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.