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Q71ZX3

- GCSPA_LISMF

UniProt

Q71ZX3 - GCSPA_LISMF

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Protein
Probable glycine dehydrogenase (decarboxylating) subunit 1
Gene
gcvPA, gcvP1, LMOf2365_1366
Organism
Listeria monocytogenes serotype 4b (strain F2365)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine catabolic process Source: InterPro
  2. nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycine dehydrogenase (decarboxylating) subunit 1 (EC:1.4.4.2)
Alternative name(s):
Glycine cleavage system P-protein subunit 1
Glycine decarboxylase subunit 1
Glycine dehydrogenase (aminomethyl-transferring) subunit 1
Gene namesi
Name:gcvPA
Synonyms:gcvP1
Ordered Locus Names:LMOf2365_1366
OrganismiListeria monocytogenes serotype 4b (strain F2365)
Taxonomic identifieri265669 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000000563: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 448448Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotation
PRO_0000166966Add
BLAST

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits By similarity.

Protein-protein interaction databases

STRINGi265669.LMOf2365_1366.

Structurei

3D structure databases

ProteinModelPortaliQ71ZX3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0403.
HOGENOMiHOG000132025.
KOiK00282.
OMAiRLVGQTE.
OrthoDBiEOG6XWV3B.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
HAMAPiMF_00712. GcvPA.
InterProiIPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 1 hit.
[Graphical view]
PIRSFiPIRSF006815. GcvPA. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

Q71ZX3-1 [UniParc]FASTAAdd to Basket

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MAKHRYLPMT EQDEKEMLDV IGVKSIDDLF QDIPEKIRFK RDYDLKPAKS    50
EPALLRELSK LASKNANTTE YASFLGAGVY SHYIPTVVDH VISRSEFYTA 100
YTPYQPEISQ GELQAIFEFQ TMIAELTGMD LANSSMYDGG TALAEAAMLA 150
SGHTKRKKIL ISGAVHPESS NVLKTYATGQ HIEVEVIPEL DGKTDIEALK 200
KALSDDIAGF VVQYPNFYGQ VEPLAELEKL VHENNSLLLV SSNPLSLGLL 250
TPPGEFGADI VVGDSQVFGI PESFGGPHCG FFAVTNKLMR KVPGRLVGET 300
VDENGKRGYV LTLQAREQHI RRDKATSNIC SNQALNALAS SVAMATLGKT 350
GLVEMAKQNL DKSHYAKQKF REKGFEVLFS DGFFNEFVVK LSKPIKEVNE 400
SLLDEGIIGG YDLGFYEEKY ENHMLVAVTE MRTKEEIDAF VASLEGAK 448
Length:448
Mass (Da):49,499
Last modified:July 5, 2004 - v1
Checksum:i3330AC3BF5414A44
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017262 Genomic DNA. Translation: AAT04141.1.
RefSeqiYP_013964.1. NC_002973.6.

Genome annotation databases

EnsemblBacteriaiAAT04141; AAT04141; LMOf2365_1366.
GeneIDi2799829.
KEGGilmf:LMOf2365_1366.
PATRICi20323971. VBILisMon105049_1373.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017262 Genomic DNA. Translation: AAT04141.1 .
RefSeqi YP_013964.1. NC_002973.6.

3D structure databases

ProteinModelPortali Q71ZX3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 265669.LMOf2365_1366.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAT04141 ; AAT04141 ; LMOf2365_1366 .
GeneIDi 2799829.
KEGGi lmf:LMOf2365_1366.
PATRICi 20323971. VBILisMon105049_1373.

Phylogenomic databases

eggNOGi COG0403.
HOGENOMi HOG000132025.
KOi K00282.
OMAi RLVGQTE.
OrthoDBi EOG6XWV3B.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
HAMAPi MF_00712. GcvPA.
InterProi IPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 1 hit.
[Graphical view ]
PIRSFi PIRSF006815. GcvPA. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F2365.

Entry informationi

Entry nameiGCSPA_LISMF
AccessioniPrimary (citable) accession number: Q71ZX3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: July 5, 2004
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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