Reviewed, UniProtKB/Swiss-Prot Q71Z86 (ACKA2_LISMF)

Names and origin

Protein names

Recommended name:
    Acetate kinase 2
    EC=2.7.2.1
Alternative name(s):
    Acetokinase 2

Gene names

Name:	ackA2
Ordered Locus Names:	LMOf2365_1603

Organism

Listeria monocytogenes serotype 4b (strain F2365) [Complete proteome] [HAMAP]

Taxonomic identifier

265669 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase 2 HAMAP MF_00020		PRO_0000107578

Sequences

	Sequence		Length	Mass (Da)
	Q71Z86-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 18F73DCDED755146	FASTA	397	43,830
	10 20 30 40 50 60 MEKTIAINAG SSSLKFQLYD MPSERVITAG IVERIGLKDS IFTITVDGEK IKEIIDIPDH 70 80 90 100 110 120 EIAVQMLLEK LINHKVIGSY DEITGIGHRV VHGGERFPES VYIDDQVIKD IEALSELAPL 130 140 150 160 170 180 HNPANVTGIK AFRKILPDVV SVAVFDTAFH QTMPPASYLY SLPYSYYEDY GIRKYGFHGT 190 200 210 220 230 240 SHKYVSERAA ELLGRPVEEL RLLTCHLGNG ASIAAIEGGK SMDTSMGFTP LAGVSMGTRS 250 260 270 280 290 300 GNIDPALIPF IMEKTGKTAE QVLDVLNKES GMLGVSGISS DLRDLEDEAA KGNDRAELAL 310 320 330 340 350 360 QVFVDRIHKY IGSYAARMNG VDAIIFTAGI GENSSYIREK VLRGLEFMGV YWDPALNQVR 370 380 390 GEERFLNYPH SPVKVIIIPT NEELMIARDV ETIKNNH

References

[1]

"Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species." Nelson K.E., Fouts D.E., Mongodin E.F., Ravel J., DeBoy R.T., Kolonay J.F., Rasko D.A., Angiuoli S.V., Gill S.R., Paulsen I.T., Peterson J.D., White O., Nelson W.C., Nierman W.C., Beanan M.J., Brinkac L.M., Daugherty S.C., Dodson R.J. , Durkin A.S., Madupu R., Haft D.H., Selengut J., Van Aken S.E., Khouri H.M., Fedorova N., Forberger H.A., Tran B., Kathariou S., Wonderling L.D., Uhlich G.A., Bayles D.O., Luchansky J.B., Fraser C.M. Nucleic Acids Res. 32:2386-2395(2004) [PubMed: 15115801] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017262 Genomic DNA. Translation: AAT04378.1.
RefSeq	YP_014201.1.
3D structure databases
SMR	Q71Z86. Positions 3-395.
ModBase	Search...
Protein-protein interaction databases
STRING	Q71Z86.
Genome annotation databases
GeneID	2798269.
GenomeReviews	Gene locus LMOf2365_1603 in contig AE017262_GR.
KEGG	lmf:LMOf2365_1603.
TIGR	LMOf2365_1603.
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	IVTFLME.
Enzyme and pathway databases
BioCyc	LMON265669:LMOF2365_1603-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA2_LISMF

Accession

Primary (citable) accession number: Q71Z86

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	July 5, 2004
Last modified:	February 9, 2010
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)