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Q71Y88 (AROB_LISMF) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:LMOf2365_1956
OrganismListeria monocytogenes serotype 4b (strain F2365) [Complete proteome] [HAMAP]
Taxonomic identifier265669 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

NAD By similarity. HAMAP MF_00110

Divalent metal cation By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3653653-dehydroquinate synthase HAMAP MF_00110
PRO_0000140753

Sequences

Sequence LengthMass (Da)Tools
Q71Y88 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 8ACF2AA2FCAF665A

FASTA36541,200
        10         20         30         40         50         60 
MPEITVRAKS KTYPVYINEF ALEDVREKWT ESLAKFSHVF VLTDEHVAEL HQAKLDAVLA 

        70         80         90        100        110        120 
DLPVVTYYVA PNGEEAKTFR VYEDVMTKLI ETGLDRKAVL IAFGGGVIGD LGGFVAATYM 

       130        140        150        160        170        180 
RGIPFYQVPT TVLAHDSAVG GKVAINHPLG KNMIGNFYQP EAVIYDTQFF ATLPEREMRS 

       190        200        210        220        230        240 
GFAEMIKHAL ISDQTLLRAL MDTFTEPKDF YTKDLTPFLQ RGIEIKANIV AQDETEQGVR 

       250        260        270        280        290        300 
AYLNFGHTFG HALEAYGNFG KWLHGEAITY GMIYALTMSE TIYGLDFDLA EFKTWLKQLG 

       310        320        330        340        350        360 
YDTTFDATVP FNKILENMRH DKKTTFNEIS MVLLEEIGEP VIFKAEDDLI FETYKRVMRN 


GGNGI

« Hide

References

[1]"Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species."
Nelson K.E., Fouts D.E., Mongodin E.F., Ravel J., DeBoy R.T., Kolonay J.F., Rasko D.A., Angiuoli S.V., Gill S.R., Paulsen I.T., Peterson J.D., White O., Nelson W.C., Nierman W.C., Beanan M.J., Brinkac L.M., Daugherty S.C., Dodson R.J. expand/collapse author list , Durkin A.S., Madupu R., Haft D.H., Selengut J., Van Aken S.E., Khouri H.M., Fedorova N., Forberger H.A., Tran B., Kathariou S., Wonderling L.D., Uhlich G.A., Bayles D.O., Luchansky J.B., Fraser C.M.
Nucleic Acids Res. 32:2386-2395(2004) [PubMed: 15115801] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: F2365.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017262 Genomic DNA. Translation: AAT04726.1.
RefSeqYP_014549.1. NC_002973.6.

3D structure databases

ProteinModelPortalQ71Y88.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ71Y88.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2798754.
GenomeReviewsGene locus LMOf2365_1956 in contig AE017262_GR.
KEGGlmf:LMOf2365_1956.
PATRIC20325205. VBILisMon105049_1962.
TIGRLMOf2365_1956.

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAAYLNFGH.
PhylomeDBQ71Y88.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycLMON265669:LMOF2365_1956-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_LISMF
AccessionPrimary (citable) accession number: Q71Y88
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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