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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Listeria monocytogenes serotype 4b (strain F2365)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:LMOf2365_2533
OrganismiListeria monocytogenes serotype 4b (strain F2365)
Taxonomic identifieri265669 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515731 – 556Arginine--tRNA ligaseAdd BLAST556

Proteomic databases

PRIDEiQ71WL8.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ71WL8.
SMRiQ71WL8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247214.
KOiK01887.
OMAiAGNQIEN.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q71WL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVMQENQIK LIEHIKQAVV QAVGLEEAEV PEILLEVPKD KKHGDYSTNI
60 70 80 90 100
AMQLARVAKK APRQIAESIV PELKKDNKLI KEVEIAGPGF INFYLDNAYL
110 120 130 140 150
TDLVPVILTE DKQYGESDFG KGEKFQIEFV SANPTGDLHL GHARGAAIGD
160 170 180 190 200
SLANIMKMAG FDVSREYYIN DAGNQINNLV LSAEARYFEA LGLDSEFPED
210 220 230 240 250
GYRGADIISL GKDLAAKYGD KYVHTSEEER RSVFRVDALA FETGKLRADL
260 270 280 290 300
EEFRVSFDEW FSETSLYEEN KVLPALERLR ENGYIYEQDG ATWLRTTDFE
310 320 330 340 350
DDKDRVLIKS DGSYTYFLPD IAYHLNKLER GFDVLIDIWG ADHHGYIPRM
360 370 380 390 400
RAAIEALGYS PNQLEVEIIQ LVHLFEDGVQ VKMSKRTGKS VTMRDLIEEV
410 420 430 440 450
GLDATRYFFA MRSSDTHMNF DMSLAKSTSN DNPVYYVQYA HARISSILRS
460 470 480 490 500
GKEQGLEVTK DADMSLLQTE AEYDLLKVLG EFADVVAEAA TKRAPHRIVR
510 520 530 540 550
YLNDLASSFH RFYNSNKVLD MDNLEVTKAR LALIKTAQIT LRNGLTLLGV

SAPEKM
Length:556
Mass (Da):62,824
Last modified:July 5, 2004 - v1
Checksum:iA1D97A7D46A72C1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017262 Genomic DNA. Translation: AAT05298.1.
RefSeqiWP_003728400.1. NC_002973.6.

Genome annotation databases

EnsemblBacteriaiAAT05298; AAT05298; LMOf2365_2533.
KEGGilmf:LMOf2365_2533.

Similar proteinsi

Entry informationi

Entry nameiSYR_LISMF
AccessioniPrimary (citable) accession number: Q71WL8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families