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Protein
Submitted name:

Endoglin

Gene

END

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Biological processi

  1. artery morphogenesis Source: Ensembl
  2. bone development Source: Ensembl
  3. cell migration involved in endocardial cushion formation Source: Ensembl
  4. cellular response to mechanical stimulus Source: Ensembl
  5. chronological cell aging Source: Ensembl
  6. extracellular matrix constituent secretion Source: Ensembl
  7. heart looping Source: Ensembl
  8. patterning of blood vessels Source: Ensembl
  9. positive regulation of collagen biosynthetic process Source: Ensembl
  10. positive regulation of gene expression Source: Ensembl
  11. positive regulation of protein phosphorylation Source: Ensembl
  12. regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  13. response to corticosteroid Source: Ensembl
  14. response to statin Source: Ensembl
  15. response to transforming growth factor beta Source: Ensembl
  16. smooth muscle tissue development Source: Ensembl
  17. vasculogenesis Source: Ensembl
  18. venous blood vessel morphogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
EndoglinImported
Gene namesi
Name:ENDImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: Ensembl
  2. endothelial microparticle Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ71V36.

Expressioni

Gene expression databases

BgeeiQ71V36.
ExpressionAtlasiQ71V36. baseline and differential.

Sequencei

Sequence statusi: Fragment.

Q71V36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
MDRGTLPLAV ALLLASCSLS PT
Length:22
Mass (Da):2,230
Last modified:July 4, 2004 - v1
Checksum:iBE9362EF8E4F8FB4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei22 – 221Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF035753 Genomic DNA. Translation: AAC32802.1.
UniGeneiHs.76753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF035753 Genomic DNA. Translation: AAC32802.1.
UniGeneiHs.76753.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ71V36.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

ChiTaRSiENG. human.

Gene expression databases

BgeeiQ71V36.
ExpressionAtlasiQ71V36. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1."
    Rius C., Smith J.D., Almendro N., Langa C., Botella L.M., Marchuk D.A., Vary C.P., Bernabeu C.
    Blood 92:4677-4690(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ71V36_HUMAN
AccessioniPrimary (citable) accession number: Q71V36
Entry historyi
Integrated into UniProtKB/TrEMBL: July 4, 2004
Last sequence update: July 4, 2004
Last modified: October 28, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.