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Protein
Submitted name:

Interferon regulatory factor 3

Gene

IRF3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 3Imported
Gene namesi
Name:IRF3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ71U93.
PeptideAtlasiQ71U93.

Expressioni

Gene expression databases

BgeeiQ71U93.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000310127.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 3026IRF tryptophan pentad repeat DNA-bindingInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IXD8. Eukaryota.
ENOG410YA4B. LUCA.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PROSITEiPS51507. IRF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q71U93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30
MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS
Length:30
Mass (Da):3,334
Last modified:July 5, 2004 - v1
Checksum:i4BDDE2DB00383899
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei30 – 301Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF112181 Genomic DNA. Translation: AAD05262.1.
UniGeneiHs.289052.
Hs.731922.
Hs.75254.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF112181 Genomic DNA. Translation: AAD05262.1.
UniGeneiHs.289052.
Hs.731922.
Hs.75254.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000310127.

Proteomic databases

PaxDbiQ71U93.
PeptideAtlasiQ71U93.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IXD8. Eukaryota.
ENOG410YA4B. LUCA.

Miscellaneous databases

ChiTaRSiIRF3. human.

Gene expression databases

BgeeiQ71U93.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PROSITEiPS51507. IRF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Lowther W., Pitha-Rowe P.
    Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Cloning and functional analysis of the human IRF-3 promoter."
    Lowther W.J., Moore P.A., Carter K.C., Pitha P.M.
    DNA Cell Biol. 18:685-692(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ71U93_HUMAN
AccessioniPrimary (citable) accession number: Q71U93
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 6, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.