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Protein

40S ribosomal protein S27

Gene

Rps27

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of the small ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 18S rRNAs (By similarity).By similarity

Cofactori

Zn2+CuratedNote: Binds 1 zinc ion per subunit.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri38 – 60C4-typeSequence analysisAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-141444. Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal.
R-RNO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-RNO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-RNO-2467813. Separation of Sister Chromatids.
R-RNO-2500257. Resolution of Sister Chromatid Cohesion.
R-RNO-5663220. RHO GTPases Activate Formins.
R-RNO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-RNO-68877. Mitotic Prometaphase.
R-RNO-72649. Translation initiation complex formation.
R-RNO-72689. Formation of a pool of free 40S subunits.
R-RNO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-RNO-72702. Ribosomal scanning and start codon recognition.
R-RNO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-RNO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-RNO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S27
Gene namesi
Name:Rps27Imported
Synonyms:S27-1Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi621045. Rps27.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001490531 – 8440S ribosomal protein S27Add BLAST84

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei11PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ71TY3.
PRIDEiQ71TY3.

PTM databases

iPTMnetiQ71TY3.
PhosphoSitePlusiQ71TY3.

Expressioni

Tissue specificityi

Expressed in the striatum, cerebellum, hippocampus, hypothalamus, pons, heart and liver.1 Publication

Gene expression databases

BgeeiENSRNOG00000016961.
GenevisibleiQ71TY3. RN.

Interactioni

Subunit structurei

Component of the small ribosomal subunit.By similarity

Protein-protein interaction databases

BioGridi250185. 1 interactor.
IntActiQ71TY3. 2 interactors.
STRINGi10116.ENSRNOP00000022897.

Structurei

3D structure databases

ProteinModelPortaliQ71TY3.
SMRiQ71TY3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri38 – 60C4-typeSequence analysisAdd BLAST23

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG1779. Eukaryota.
COG2051. LUCA.
GeneTreeiENSGT00390000013514.
HOVERGENiHBG000252.
InParanoidiQ71TY3.
KOiK02978.
OMAiCDNCSTV.
OrthoDBiEOG091G157G.
PhylomeDBiQ71TY3.
TreeFamiTF300265.

Family and domain databases

Gene3Di2.20.25.100. 1 hit.
HAMAPiMF_00371. Ribosomal_S27e. 1 hit.
InterProiView protein in InterPro
IPR000592. Ribosomal_S27e.
IPR023407. Ribosomal_S27e_Zn-bd_dom_sf.
IPR011332. Ribosomal_zn-bd.
PANTHERiPTHR11594. PTHR11594. 1 hit.
PfamiView protein in Pfam
PF01667. Ribosomal_S27e. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD004466. Ribosomal_S27e. 1 hit.
SUPFAMiSSF57829. SSF57829. 1 hit.
PROSITEiView protein in PROSITE
PS01168. RIBOSOMAL_S27E. 1 hit.

Sequencei

Sequence statusi: Complete.

Q71TY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLAKDLLHP SPEEEKRKHK KKRLVQSPNS YFMDVKCPGC YKITTVFSHA
60 70 80
QTVVLCVGCS TVLCQPTGGK ARLTEGCSFR RKQH
Length:84
Mass (Da):9,461
Last modified:January 23, 2007 - v3
Checksum:i242C4466AC8A8900
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF184893 mRNA. Translation: AAD56582.1.
BC061539 mRNA. Translation: AAH61539.1.
RefSeqiNP_446049.1. NM_053597.3.
UniGeneiRn.144623.
Rn.153914.

Genome annotation databases

EnsembliENSRNOT00000022897; ENSRNOP00000022897; ENSRNOG00000016961.
GeneIDi94266.
KEGGirno:94266.
UCSCiRGD:621045. rat.

Similar proteinsi

Entry informationi

Entry nameiRS27_RAT
AccessioniPrimary (citable) accession number: Q71TY3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: January 23, 2007
Last modified: November 22, 2017
This is version 111 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families