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Protein
Submitted name:

Frizzled-10 like protein

Gene

Fzd10

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, ReceptorSAAS annotation
Biological processWnt signaling pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Frizzled-10 like proteinImported
Gene namesi
Name:Fzd10Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2136761 Fzd10

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei264 – 288HelicalSequence analysisAdd BLAST25
Transmembranei300 – 320HelicalSequence analysisAdd BLAST21
Transmembranei348 – 373HelicalSequence analysisAdd BLAST26
Transmembranei393 – 413HelicalSequence analysisAdd BLAST21
Transmembranei433 – 460HelicalSequence analysisAdd BLAST28
Transmembranei481 – 502HelicalSequence analysisAdd BLAST22
Transmembranei541 – 560HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi71 ↔ 132PROSITE-ProRule annotation
Disulfide bondi79 ↔ 125PROSITE-ProRule annotation
Disulfide bondi116 ↔ 154PROSITE-ProRule annotation
Disulfide bondi143 ↔ 184PROSITE-ProRule annotation
Disulfide bondi147 ↔ 171PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ71S95
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 187FZInterPro annotationAdd BLAST122
Domaini264 – 567G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST304

Sequence similaritiesi

Belongs to the G-protein coupled receptor Fz/Smo family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3577 Eukaryota
ENOG410XRC8 LUCA
HOGENOMiHOG000233236
HOVERGENiHBG006977
PhylomeDBiQ71S95

Family and domain databases

Gene3Di1.10.2000.101 hit
InterProiView protein in InterPro
IPR015526 Frizzled/SFRP
IPR000539 Frizzled/Smoothened_TM
IPR020067 Frizzled_dom
IPR036790 Frizzled_dom_sf
IPR026549 FZD10
IPR017981 GPCR_2-like
PANTHERiPTHR11309 PTHR11309, 1 hit
PTHR11309:SF86 PTHR11309:SF86, 1 hit
PfamiView protein in Pfam
PF01534 Frizzled, 1 hit
PF01392 Fz, 1 hit
PRINTSiPR00489 FRIZZLED
SMARTiView protein in SMART
SM00063 FRI, 1 hit
SM01330 Frizzled, 1 hit
SUPFAMiSSF63501 SSF63501, 1 hit
PROSITEiView protein in PROSITE
PS50038 FZ, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit

Sequencei

Sequence statusi: Complete.

Q71S95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGMRGGPSRG AERGQQQQPV PGSGGPERRW DIAGATMQHP GPRLWLVLQV
60 70 80 90 100
MIGSCTAISS MDLERPGDGK CQPVEIPMCK DIGYNTTRMP NLMGHENQRE
110 120 130 140 150
AAIQLHEFAP LVEYGCHSHL RFFLCSLYAP MCTEQVSTPI PACRVMCEQA
160 170 180 190 200
RLKCSPIMEQ FKFRWPDSLD CSKLPNKNDP NYLCMEAPNN GSDEPSRGSG
210 220 230 240 250
MFPPLFRPQR PHSAQEHPLK DGGPGRAGCD NPGKFHHVEK SESCAPLCTP
260 270 280 290 300
GVDVYWSRDD KRFAVVWLAI WSVLCFFSSA FTVLTFLIDP SRFRYPERPI
310 320 330 340 350
IFLSMCYCVY SVGYIIRLFA GAESIACDRD SGQLYVIQEG LESTGCTLVF
360 370 380 390 400
LVLYYFGMAS SLWWVVLTLT WFLAAGKKWG HEAIEANSSY FHLAAWAIPA
410 420 430 440 450
VKTILILVMR RVAGDELTGV CYVGSMDVNA LTGFVLVPLA CYLVIGTSFI
460 470 480 490 500
LSGFVALFHI RRVMKTGGEN TDKLEKLMVR IGVFSLLYTV PATCVIACYF
510 520 530 540 550
YERLNMDYWK MLATQHKCKM NNQTKTPDCL MTTSIPAVEV FMVKVSMLLV
560 570 580 590 600
VGITSGVWVW TSKTLQSWQH VCSRGLKRKS RRKPASVVTS AGIYKKAQHP
610
QKPHLGKYEL PAQPSACV
Length:618
Mass (Da):69,036
Last modified:July 5, 2004 - v1
Checksum:iA1B2F98C1C0D3738
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF310970 mRNA Translation: AAQ14553.1
UniGeneiMm.197628

Similar proteinsi

Entry informationi

Entry nameiQ71S95_MOUSE
AccessioniPrimary (citable) accession number: Q71S95
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 28, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)