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Q71S95 (Q71S95_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Fzd10 MGI 2136761
OrganismMus musculus (Mouse) EMBL AAQ14553.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length618 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains FZ (frizzled) domain. SAAS SAAS017981

Ontologies

Keywords
   Biological processWnt signaling pathway SAAS SAAS020067
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix SAAS SAAS020067
   Molecular functionDevelopmental protein SAAS SAAS020067
Receptor SAAS SAAS020067
   PTMDisulfide bond SAAS SAAS017981
Gene Ontology (GO)
   Biological_processWnt signaling pathway

Inferred from genetic interaction PubMed 15923619. Source: MGI

brain development

Inferred from Biological aspect of Ancestor. Source: RefGenome

canonical Wnt signaling pathway

Inferred from Biological aspect of Ancestor. Source: RefGenome

gonad development

Inferred from Biological aspect of Ancestor. Source: RefGenome

negative regulation of Rho GTPase activity

Inferred from electronic annotation. Source: Ensembl

non-canonical Wnt signaling pathway via JNK cascade

Inferred from electronic annotation. Source: Ensembl

positive regulation of JUN kinase activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of Rac GTPase activity

Inferred from electronic annotation. Source: Ensembl

regulation of actin cytoskeleton organization

Inferred from electronic annotation. Source: Ensembl

regulation of transcription from RNA polymerase II promoter

Inferred from Biological aspect of Ancestor. Source: RefGenome

vasculature development

Inferred from Biological aspect of Ancestor. Source: RefGenome

   Cellular_componentcell projection

Inferred from Biological aspect of Ancestor. Source: RefGenome

cell surface

Inferred from electronic annotation. Source: Ensembl

cytoplasm

Inferred from Biological aspect of Ancestor. Source: RefGenome

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from Biological aspect of Ancestor. Source: RefGenome

   Molecular_functionG-protein coupled receptor activity

Inferred from electronic annotation. Source: UniProtKB-KW

PDZ domain binding

Inferred from Biological aspect of Ancestor. Source: RefGenome

Wnt-activated receptor activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

Wnt-protein binding

Inferred from physical interaction PubMed 15923619. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q71S95 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: A1B2F98C1C0D3738

FASTA61869,036
        10         20         30         40         50         60 
MGMRGGPSRG AERGQQQQPV PGSGGPERRW DIAGATMQHP GPRLWLVLQV MIGSCTAISS 

        70         80         90        100        110        120 
MDLERPGDGK CQPVEIPMCK DIGYNTTRMP NLMGHENQRE AAIQLHEFAP LVEYGCHSHL 

       130        140        150        160        170        180 
RFFLCSLYAP MCTEQVSTPI PACRVMCEQA RLKCSPIMEQ FKFRWPDSLD CSKLPNKNDP 

       190        200        210        220        230        240 
NYLCMEAPNN GSDEPSRGSG MFPPLFRPQR PHSAQEHPLK DGGPGRAGCD NPGKFHHVEK 

       250        260        270        280        290        300 
SESCAPLCTP GVDVYWSRDD KRFAVVWLAI WSVLCFFSSA FTVLTFLIDP SRFRYPERPI 

       310        320        330        340        350        360 
IFLSMCYCVY SVGYIIRLFA GAESIACDRD SGQLYVIQEG LESTGCTLVF LVLYYFGMAS 

       370        380        390        400        410        420 
SLWWVVLTLT WFLAAGKKWG HEAIEANSSY FHLAAWAIPA VKTILILVMR RVAGDELTGV 

       430        440        450        460        470        480 
CYVGSMDVNA LTGFVLVPLA CYLVIGTSFI LSGFVALFHI RRVMKTGGEN TDKLEKLMVR 

       490        500        510        520        530        540 
IGVFSLLYTV PATCVIACYF YERLNMDYWK MLATQHKCKM NNQTKTPDCL MTTSIPAVEV 

       550        560        570        580        590        600 
FMVKVSMLLV VGITSGVWVW TSKTLQSWQH VCSRGLKRKS RRKPASVVTS AGIYKKAQHP 

       610 
QKPHLGKYEL PAQPSACV 

« Hide

References

[1]"Cloning and expression of a mouse homolog of Frizzled-10."
Yoshikawa Y., Shiraga H., Kawakami Y., Nohno T., Takada S.
Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF310970 mRNA. Translation: AAQ14553.1.
UniGeneMm.197628.

3D structure databases

ProteinModelPortalQ71S95.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSI93.001.

Proteomic databases

PRIDEQ71S95.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:2136761. Fzd10.

Phylogenomic databases

HOGENOMHOG000233236.
HOVERGENHBG006977.
InParanoidQ71S95.
PhylomeDBQ71S95.

Gene expression databases

ArrayExpressQ71S95.
BgeeQ71S95.
GenevestigatorQ71S95.

Family and domain databases

Gene3D1.10.2000.10. 1 hit.
InterProIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026549. FZD10.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF86. PTHR11309:SF86. 1 hit.
PfamPF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view]
PRINTSPR00489. FRIZZLED.
SMARTSM00063. FRI. 1 hit.
[Graphical view]
SUPFAMSSF63501. SSF63501. 1 hit.
PROSITEPS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ71S95_MOUSE
AccessionPrimary (citable) accession number: Q71S95
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)