Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q71S95

- Q71S95_MOUSE

UniProt

Q71S95 - Q71S95_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Frizzled-10 like protein

Gene

Fzd10

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. PDZ domain binding Source: RefGenome
  2. Wnt-activated receptor activity Source: RefGenome
  3. Wnt-protein binding Source: MGI

GO - Biological processi

  1. brain development Source: RefGenome
  2. canonical Wnt signaling pathway Source: RefGenome
  3. gonad development Source: RefGenome
  4. negative regulation of Rho GTPase activity Source: Ensembl
  5. non-canonical Wnt signaling pathway via JNK cascade Source: Ensembl
  6. positive regulation of JUN kinase activity Source: Ensembl
  7. positive regulation of Rac GTPase activity Source: Ensembl
  8. regulation of actin cytoskeleton organization Source: Ensembl
  9. regulation of transcription from RNA polymerase II promoter Source: RefGenome
  10. vasculature development Source: RefGenome
  11. Wnt signaling pathway Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinSAAS annotation, ReceptorSAAS annotation

Keywords - Biological processi

Wnt signaling pathwaySAAS annotation

Protein family/group databases

MEROPSiI93.001.

Names & Taxonomyi

Protein namesi
Submitted name:
Frizzled-10 like proteinImported
Gene namesi
Name:Fzd10Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2136761. Fzd10.

Subcellular locationi

GO - Cellular componenti

  1. cell projection Source: RefGenome
  2. cell surface Source: Ensembl
  3. cytoplasm Source: RefGenome
  4. integral component of membrane Source: UniProtKB-KW
  5. plasma membrane Source: RefGenome
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PRIDEiQ71S95.

Expressioni

Gene expression databases

BgeeiQ71S95.
ExpressionAtlasiQ71S95. baseline.
GenevestigatoriQ71S95.

Structurei

3D structure databases

ProteinModelPortaliQ71S95.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains FZ (frizzled) domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOGENOMiHOG000233236.
HOVERGENiHBG006977.
PhylomeDBiQ71S95.

Family and domain databases

Gene3Di1.10.2000.10. 1 hit.
InterProiIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026549. FZD10.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF86. PTHR11309:SF86. 1 hit.
PfamiPF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view]
PRINTSiPR00489. FRIZZLED.
SMARTiSM00063. FRI. 1 hit.
[Graphical view]
SUPFAMiSSF63501. SSF63501. 1 hit.
PROSITEiPS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q71S95-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGMRGGPSRG AERGQQQQPV PGSGGPERRW DIAGATMQHP GPRLWLVLQV
60 70 80 90 100
MIGSCTAISS MDLERPGDGK CQPVEIPMCK DIGYNTTRMP NLMGHENQRE
110 120 130 140 150
AAIQLHEFAP LVEYGCHSHL RFFLCSLYAP MCTEQVSTPI PACRVMCEQA
160 170 180 190 200
RLKCSPIMEQ FKFRWPDSLD CSKLPNKNDP NYLCMEAPNN GSDEPSRGSG
210 220 230 240 250
MFPPLFRPQR PHSAQEHPLK DGGPGRAGCD NPGKFHHVEK SESCAPLCTP
260 270 280 290 300
GVDVYWSRDD KRFAVVWLAI WSVLCFFSSA FTVLTFLIDP SRFRYPERPI
310 320 330 340 350
IFLSMCYCVY SVGYIIRLFA GAESIACDRD SGQLYVIQEG LESTGCTLVF
360 370 380 390 400
LVLYYFGMAS SLWWVVLTLT WFLAAGKKWG HEAIEANSSY FHLAAWAIPA
410 420 430 440 450
VKTILILVMR RVAGDELTGV CYVGSMDVNA LTGFVLVPLA CYLVIGTSFI
460 470 480 490 500
LSGFVALFHI RRVMKTGGEN TDKLEKLMVR IGVFSLLYTV PATCVIACYF
510 520 530 540 550
YERLNMDYWK MLATQHKCKM NNQTKTPDCL MTTSIPAVEV FMVKVSMLLV
560 570 580 590 600
VGITSGVWVW TSKTLQSWQH VCSRGLKRKS RRKPASVVTS AGIYKKAQHP
610
QKPHLGKYEL PAQPSACV
Length:618
Mass (Da):69,036
Last modified:July 5, 2004 - v1
Checksum:iA1B2F98C1C0D3738
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF310970 mRNA. Translation: AAQ14553.1.
UniGeneiMm.197628.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF310970 mRNA. Translation: AAQ14553.1 .
UniGenei Mm.197628.

3D structure databases

ProteinModelPortali Q71S95.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I93.001.

Proteomic databases

PRIDEi Q71S95.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:2136761. Fzd10.

Phylogenomic databases

HOGENOMi HOG000233236.
HOVERGENi HBG006977.
PhylomeDBi Q71S95.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q71S95.
ExpressionAtlasi Q71S95. baseline.
Genevestigatori Q71S95.

Family and domain databases

Gene3Di 1.10.2000.10. 1 hit.
InterProi IPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026549. FZD10.
IPR017981. GPCR_2-like.
[Graphical view ]
PANTHERi PTHR11309. PTHR11309. 1 hit.
PTHR11309:SF86. PTHR11309:SF86. 1 hit.
Pfami PF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view ]
PRINTSi PR00489. FRIZZLED.
SMARTi SM00063. FRI. 1 hit.
[Graphical view ]
SUPFAMi SSF63501. SSF63501. 1 hit.
PROSITEi PS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and expression of a mouse homolog of Frizzled-10."
    Yoshikawa Y., Shiraga H., Kawakami Y., Nohno T., Takada S.
    Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ71S95_MOUSE
AccessioniPrimary (citable) accession number: Q71S95
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)