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Q71S95

- Q71S95_MOUSE

UniProt

Q71S95 - Q71S95_MOUSE

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Protein
Submitted name: Frizzled-10 like protein
Gene
Fzd10
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. PDZ domain binding Source: RefGenome
  3. Wnt-activated receptor activity Source: RefGenome
  4. Wnt-protein binding Source: MGI

GO - Biological processi

  1. Wnt signaling pathway Source: MGI
  2. brain development Source: RefGenome
  3. canonical Wnt signaling pathway Source: RefGenome
  4. gonad development Source: RefGenome
  5. negative regulation of Rho GTPase activity Source: Ensembl
  6. non-canonical Wnt signaling pathway via JNK cascade Source: Ensembl
  7. positive regulation of JUN kinase activity Source: Ensembl
  8. positive regulation of Rac GTPase activity Source: Ensembl
  9. regulation of actin cytoskeleton organization Source: Ensembl
  10. regulation of transcription from RNA polymerase II promoter Source: RefGenome
  11. vasculature development Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinSAAS annotations, ReceptorSAAS annotations

Keywords - Biological processi

Wnt signaling pathwaySAAS annotations

Protein family/group databases

MEROPSiI93.001.

Names & Taxonomyi

Protein namesi
Submitted name:
Frizzled-10 like proteinImported
Gene namesi
Name:Fzd10Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2136761. Fzd10.

Subcellular locationi

GO - Cellular componenti

  1. cell projection Source: RefGenome
  2. cell surface Source: Ensembl
  3. cytoplasm Source: RefGenome
  4. integral component of membrane Source: UniProtKB-KW
  5. plasma membrane Source: RefGenome
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Proteomic databases

PRIDEiQ71S95.

Expressioni

Gene expression databases

ArrayExpressiQ71S95.
BgeeiQ71S95.
GenevestigatoriQ71S95.

Structurei

3D structure databases

ProteinModelPortaliQ71S95.

Family & Domainsi

Sequence similaritiesi

Contains FZ (frizzled) domain.SAAS annotations

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOGENOMiHOG000233236.
HOVERGENiHBG006977.
InParanoidiQ71S95.
PhylomeDBiQ71S95.

Family and domain databases

Gene3Di1.10.2000.10. 1 hit.
InterProiIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026549. FZD10.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF86. PTHR11309:SF86. 1 hit.
PfamiPF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view]
PRINTSiPR00489. FRIZZLED.
SMARTiSM00063. FRI. 1 hit.
[Graphical view]
SUPFAMiSSF63501. SSF63501. 1 hit.
PROSITEiPS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q71S95-1 [UniParc]FASTAAdd to Basket

« Hide

MGMRGGPSRG AERGQQQQPV PGSGGPERRW DIAGATMQHP GPRLWLVLQV    50
MIGSCTAISS MDLERPGDGK CQPVEIPMCK DIGYNTTRMP NLMGHENQRE 100
AAIQLHEFAP LVEYGCHSHL RFFLCSLYAP MCTEQVSTPI PACRVMCEQA 150
RLKCSPIMEQ FKFRWPDSLD CSKLPNKNDP NYLCMEAPNN GSDEPSRGSG 200
MFPPLFRPQR PHSAQEHPLK DGGPGRAGCD NPGKFHHVEK SESCAPLCTP 250
GVDVYWSRDD KRFAVVWLAI WSVLCFFSSA FTVLTFLIDP SRFRYPERPI 300
IFLSMCYCVY SVGYIIRLFA GAESIACDRD SGQLYVIQEG LESTGCTLVF 350
LVLYYFGMAS SLWWVVLTLT WFLAAGKKWG HEAIEANSSY FHLAAWAIPA 400
VKTILILVMR RVAGDELTGV CYVGSMDVNA LTGFVLVPLA CYLVIGTSFI 450
LSGFVALFHI RRVMKTGGEN TDKLEKLMVR IGVFSLLYTV PATCVIACYF 500
YERLNMDYWK MLATQHKCKM NNQTKTPDCL MTTSIPAVEV FMVKVSMLLV 550
VGITSGVWVW TSKTLQSWQH VCSRGLKRKS RRKPASVVTS AGIYKKAQHP 600
QKPHLGKYEL PAQPSACV 618
Length:618
Mass (Da):69,036
Last modified:July 5, 2004 - v1
Checksum:iA1B2F98C1C0D3738
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF310970 mRNA. Translation: AAQ14553.1.
UniGeneiMm.197628.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF310970 mRNA. Translation: AAQ14553.1 .
UniGenei Mm.197628.

3D structure databases

ProteinModelPortali Q71S95.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I93.001.

Proteomic databases

PRIDEi Q71S95.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:2136761. Fzd10.

Phylogenomic databases

HOGENOMi HOG000233236.
HOVERGENi HBG006977.
InParanoidi Q71S95.
PhylomeDBi Q71S95.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi Q71S95.
Bgeei Q71S95.
Genevestigatori Q71S95.

Family and domain databases

Gene3Di 1.10.2000.10. 1 hit.
InterProi IPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026549. FZD10.
IPR017981. GPCR_2-like.
[Graphical view ]
PANTHERi PTHR11309. PTHR11309. 1 hit.
PTHR11309:SF86. PTHR11309:SF86. 1 hit.
Pfami PF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view ]
PRINTSi PR00489. FRIZZLED.
SMARTi SM00063. FRI. 1 hit.
[Graphical view ]
SUPFAMi SSF63501. SSF63501. 1 hit.
PROSITEi PS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and expression of a mouse homolog of Frizzled-10."
    Yoshikawa Y., Shiraga H., Kawakami Y., Nohno T., Takada S.
    Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ71S95_MOUSE
AccessioniPrimary (citable) accession number: Q71S95
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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