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Protein
Submitted name:

KRAB zinc finger protein

Gene

ZNF331

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
KRAB zinc finger proteinImported
Submitted name:
Zinc finger protein 331Imported
Gene namesi
Name:ZNF331Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:15489. ZNF331.

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134866703.

Structurei

3D structure databases

ProteinModelPortaliQ71QC6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00780000121862.
KOiK09228.

Family and domain databases

InterProiIPR001909. Krueppel-associated_box.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q71QC6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQGLVTFAD VAIDFSQEEW ACLNSAQRDL YWDVMLENYS NLVSLDLESA
60
YENKSLPTEK NIHEIR
Length:66
Mass (Da):7,626
Last modified:July 5, 2004 - v1
Checksum:i03CB87D55F245684
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei66 – 661Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011487 Genomic DNA. No translation available.
AF412401 mRNA. Translation: AAQ03248.1.
RefSeqiNP_001073376.1. NM_001079907.1.
UniGeneiHs.185674.

Genome annotation databases

EnsembliENST00000504493; ENSP00000425517; ENSG00000130844.
GeneIDi55422.
KEGGihsa:55422.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011487 Genomic DNA. No translation available.
AF412401 mRNA. Translation: AAQ03248.1.
RefSeqiNP_001073376.1. NM_001079907.1.
UniGeneiHs.185674.

3D structure databases

ProteinModelPortaliQ71QC6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi55422.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000504493; ENSP00000425517; ENSG00000130844.
GeneIDi55422.
KEGGihsa:55422.

Organism-specific databases

CTDi55422.
HGNCiHGNC:15489. ZNF331.
PharmGKBiPA134866703.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00780000121862.
KOiK09228.

Miscellaneous databases

ChiTaRSiZNF331. human.
GenomeRNAii55422.
NextBioi59806.

Family and domain databases

InterProiIPR001909. Krueppel-associated_box.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A KRAB zinc finger protein gene is the potential target of 19q13 translocation in benign thyroid tumors."
    Rippe V., Belge G., Meiboom M., Kazmierczak B., Fusco A., Bullerdiek J.
    Genes Chromosomes Cancer 26:229-236(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.
  2. "Further molecular characterization of ZNF331 supports its possible role in the development of thyroid follicular adenomas."
    Meiboom M., Gehrken I., Rippe V., Murua Escobar H., Belge G., Bullerdiek J.
    Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.
  3. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ71QC6_HUMAN
AccessioniPrimary (citable) accession number: Q71QC6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 4, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.