ID   Q71QC3_HUMAN            Unreviewed;        72 AA.
AC   Q71QC3;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   SubName: Full=KRAB zinc finger protein {ECO:0000313|EMBL:AAQ03251.1};
DE   Flags: Fragment;
GN   Name=ZNF331 {ECO:0000313|EMBL:AAQ03251.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAQ03251.1};
RN   [1] {ECO:0000313|EMBL:AAQ03251.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Testis {ECO:0000313|EMBL:AAQ03251.1};
RX   PubMed=10502321;
RX   DOI=10.1002/(SICI)1098-2264(199911)26:3<229::AID-GCC7>3.3.CO;2-A;
RA   Rippe V., Belge G., Meiboom M., Kazmierczak B., Fusco A., Bullerdiek J.;
RT   "A KRAB zinc finger protein gene is the potential target of 19q13
RT   translocation in benign thyroid tumors.";
RL   Genes Chromosomes Cancer 26:229-236(1999).
RN   [2] {ECO:0000313|EMBL:AAQ03251.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Testis {ECO:0000313|EMBL:AAQ03251.1};
RA   Meiboom M., Gehrken I., Rippe V., Murua Escobar H., Belge G.,
RA   Bullerdiek J.;
RT   "Further molecular characterization of ZNF331 supports its possible role in
RT   the development of thyroid follicular adenomas.";
RL   Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000256|ARBA:ARBA00006991}.
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DR   EMBL; AF412404; AAQ03251.1; -; mRNA.
DR   AlphaFoldDB; Q71QC3; -.
DR   PeptideAtlas; Q71QC3; -.
DR   ChiTaRS; ZNF331; human.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd07765; KRAB_A-box; 1.
DR   Gene3D; 6.10.140.140; -; 1.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036051; KRAB_dom_sf.
DR   PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR   PANTHER; PTHR23232:SF138; ZINC FINGER PROTEIN 589; 1.
DR   Pfam; PF01352; KRAB; 1.
DR   SMART; SM00349; KRAB; 1.
DR   SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR   PROSITE; PS50805; KRAB; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          6..72
FT                   /note="KRAB"
FT                   /evidence="ECO:0000259|PROSITE:PS50805"
FT   NON_TER         72
FT                   /evidence="ECO:0000313|EMBL:AAQ03251.1"
SQ   SEQUENCE   72 AA;  8270 MW;  A90C5AA397C373CB CRC64;
     MAQGLVTFAD VAIDFSQEEW ACLNSAQRDL YWDVMLENYS NLVSLDLESA YENKSLPTEK
     NIHEIRASKR NS
//