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Q71G59

- Q71G59_DANRE

UniProt

Q71G59 - Q71G59_DANRE

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Protein
Submitted name:

Matrix metalloproteinase 13

Gene

mmp13a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei223 – 2231UniRule annotation

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. metalloendopeptidase activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, MetalloproteaseSAAS annotation, Protease

Keywords - Ligandi

CalciumSAAS annotation, Metal-bindingSAAS annotation, ZincSAAS annotation

Protein family/group databases

MEROPSiM10.013.

Names & Taxonomyi

Protein namesi
Submitted name:
Matrix metalloproteinase 13Imported
Gene namesi
Name:mmp13aImported
Synonyms:mmp13Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-031202-2. mmp13a.

Subcellular locationi

GO - Cellular componenti

  1. extracellular matrix Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000026466.

Structurei

3D structure databases

ProteinModelPortaliQ71G59.
SMRiQ71G59. Positions 103-268.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains hemopexin repeats.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

HOGENOMiHOG000217927.
HOVERGENiHBG052484.

Family and domain databases

Gene3Di2.110.10.10. 1 hit.
3.40.390.10. 1 hit.
InterProiIPR000585. Hemopexin-like_dom.
IPR018487. Hemopexin-like_repeat.
IPR018486. Hemopexin_CS.
IPR024079. MetalloPept_cat_dom.
IPR001818. Pept_M10_metallopeptidase.
IPR021190. Pept_M10A.
IPR016293. Pept_M10A_stromelysin-type.
IPR021158. Pept_M10A_Zn_BS.
IPR006026. Peptidase_Metallo.
IPR002477. Peptidoglycan-bd-like.
[Graphical view]
PfamiPF00045. Hemopexin. 3 hits.
PF00413. Peptidase_M10. 1 hit.
PF01471. PG_binding_1. 1 hit.
[Graphical view]
PIRSFiPIRSF001191. Peptidase_M10A_matrix. 1 hit.
PRINTSiPR00138. MATRIXIN.
SMARTiSM00120. HX. 4 hits.
SM00235. ZnMc. 1 hit.
[Graphical view]
SUPFAMiSSF47090. SSF47090. 1 hit.
SSF50923. SSF50923. 1 hit.
PROSITEiPS00546. CYSTEINE_SWITCH. 1 hit.
PS00024. HEMOPEXIN. 1 hit.
PS51642. HEMOPEXIN_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q71G59 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKTCFRLCVF ITLLFSGHSS PIAPPAGGDQ DTLAENYLTR LYGLPKPAQN
60 70 80 90 100
PSPSGGEKRS SDVSLRLKEM QQFFKLKVSG KLDQETLEVM KKPRCGVPDI
110 120 130 140 150
KAYSTFAGDY KWKKHQLTYR IGNYTPDMSV AEVDDSISKA LKVWADVTPL
160 170 180 190 200
RFTRIYSGTA DIMISFATGD HRDGYPFDGP NGFLAHAFPP FEGIGGDAHF
210 220 230 240 250
DDDETFSYRS PQYYNLFLVA AHEFGHSLGL EHSQDPGALM YPTYVYRDVD
260 270 280 290 300
RFVLPRDDVN GIQSLYGPNT DVNTDDSKPT PPVTPNTCDP NLVLDAVTML
310 320 330 340 350
RGEIMFFKNS FFWRSYPQSA DVEQQLIKSF WPEAPDNIDA AFESVMQDKV
360 370 380 390 400
FLIKGEKVWA LYGYDMVQGY PKSLSMFRLP KNVRKIDAVL YKEDSNSILF
410 420 430 440 450
FANNQVYSYN EGIRQMDKGF PKPVEEVFPG MTGKVTAAFQ YRGLNYLFSG
460 470
SKMLEFGSNN RLFRVLNNNY FLPCK
Length:475
Mass (Da):53,792
Last modified:July 5, 2004 - v1
Checksum:i90F93E82B37B2CFD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF506756 mRNA. Translation: AAQ07962.1.
UniGeneiDr.81475.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF506756 mRNA. Translation: AAQ07962.1 .
UniGenei Dr.81475.

3D structure databases

ProteinModelPortali Q71G59.
SMRi Q71G59. Positions 103-268.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7955.ENSDARP00000026466.

Protein family/group databases

MEROPSi M10.013.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

ZFINi ZDB-GENE-031202-2. mmp13a.

Phylogenomic databases

HOGENOMi HOG000217927.
HOVERGENi HBG052484.

Family and domain databases

Gene3Di 2.110.10.10. 1 hit.
3.40.390.10. 1 hit.
InterProi IPR000585. Hemopexin-like_dom.
IPR018487. Hemopexin-like_repeat.
IPR018486. Hemopexin_CS.
IPR024079. MetalloPept_cat_dom.
IPR001818. Pept_M10_metallopeptidase.
IPR021190. Pept_M10A.
IPR016293. Pept_M10A_stromelysin-type.
IPR021158. Pept_M10A_Zn_BS.
IPR006026. Peptidase_Metallo.
IPR002477. Peptidoglycan-bd-like.
[Graphical view ]
Pfami PF00045. Hemopexin. 3 hits.
PF00413. Peptidase_M10. 1 hit.
PF01471. PG_binding_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF001191. Peptidase_M10A_matrix. 1 hit.
PRINTSi PR00138. MATRIXIN.
SMARTi SM00120. HX. 4 hits.
SM00235. ZnMc. 1 hit.
[Graphical view ]
SUPFAMi SSF47090. SSF47090. 1 hit.
SSF50923. SSF50923. 1 hit.
PROSITEi PS00546. CYSTEINE_SWITCH. 1 hit.
PS00024. HEMOPEXIN. 1 hit.
PS51642. HEMOPEXIN_2. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and Functional Analysis of Zebrafish MMP13."
    Bai S., Sarras M.P.Jr.
    Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ71G59_DANRE
AccessioniPrimary (citable) accession number: Q71G59
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)