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Q71G59

- Q71G59_DANRE

UniProt

Q71G59 - Q71G59_DANRE

Protein
Submitted name:

Matrix metalloproteinase 13

Gene

mmp13a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei223 – 2231UniRule annotation

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. metalloendopeptidase activity Source: InterPro
    3. zinc ion binding Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, MetalloproteaseSAAS annotation, Protease

    Keywords - Ligandi

    CalciumSAAS annotation, Metal-bindingSAAS annotation, ZincSAAS annotation

    Protein family/group databases

    MEROPSiM10.013.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Matrix metalloproteinase 13Imported
    Gene namesi
    Name:mmp13aImported
    Synonyms:mmp13Imported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

    Organism-specific databases

    ZFINiZDB-GENE-031202-2. mmp13a.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular matrix Source: InterPro

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi7955.ENSDARP00000026466.

    Structurei

    3D structure databases

    ProteinModelPortaliQ71G59.
    SMRiQ71G59. Positions 103-268.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains hemopexin repeats.SAAS annotation

    Keywords - Domaini

    RepeatSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000217927.
    HOVERGENiHBG052484.
    InParanoidiQ71G59.

    Family and domain databases

    Gene3Di2.110.10.10. 1 hit.
    3.40.390.10. 1 hit.
    InterProiIPR000585. Hemopexin-like_dom.
    IPR018487. Hemopexin-like_repeat.
    IPR018486. Hemopexin_CS.
    IPR024079. MetalloPept_cat_dom.
    IPR001818. Pept_M10_metallopeptidase.
    IPR021190. Pept_M10A.
    IPR016293. Pept_M10A_stromelysin-type.
    IPR021158. Pept_M10A_Zn_BS.
    IPR006026. Peptidase_Metallo.
    IPR002477. Peptidoglycan-bd-like.
    [Graphical view]
    PfamiPF00045. Hemopexin. 3 hits.
    PF00413. Peptidase_M10. 1 hit.
    PF01471. PG_binding_1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001191. Peptidase_M10A_matrix. 1 hit.
    PRINTSiPR00138. MATRIXIN.
    SMARTiSM00120. HX. 4 hits.
    SM00235. ZnMc. 1 hit.
    [Graphical view]
    SUPFAMiSSF47090. SSF47090. 1 hit.
    SSF50923. SSF50923. 1 hit.
    PROSITEiPS00546. CYSTEINE_SWITCH. 1 hit.
    PS00024. HEMOPEXIN. 1 hit.
    PS51642. HEMOPEXIN_2. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q71G59-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKTCFRLCVF ITLLFSGHSS PIAPPAGGDQ DTLAENYLTR LYGLPKPAQN    50
    PSPSGGEKRS SDVSLRLKEM QQFFKLKVSG KLDQETLEVM KKPRCGVPDI 100
    KAYSTFAGDY KWKKHQLTYR IGNYTPDMSV AEVDDSISKA LKVWADVTPL 150
    RFTRIYSGTA DIMISFATGD HRDGYPFDGP NGFLAHAFPP FEGIGGDAHF 200
    DDDETFSYRS PQYYNLFLVA AHEFGHSLGL EHSQDPGALM YPTYVYRDVD 250
    RFVLPRDDVN GIQSLYGPNT DVNTDDSKPT PPVTPNTCDP NLVLDAVTML 300
    RGEIMFFKNS FFWRSYPQSA DVEQQLIKSF WPEAPDNIDA AFESVMQDKV 350
    FLIKGEKVWA LYGYDMVQGY PKSLSMFRLP KNVRKIDAVL YKEDSNSILF 400
    FANNQVYSYN EGIRQMDKGF PKPVEEVFPG MTGKVTAAFQ YRGLNYLFSG 450
    SKMLEFGSNN RLFRVLNNNY FLPCK 475
    Length:475
    Mass (Da):53,792
    Last modified:July 5, 2004 - v1
    Checksum:i90F93E82B37B2CFD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF506756 mRNA. Translation: AAQ07962.1.
    UniGeneiDr.81475.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF506756 mRNA. Translation: AAQ07962.1 .
    UniGenei Dr.81475.

    3D structure databases

    ProteinModelPortali Q71G59.
    SMRi Q71G59. Positions 103-268.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7955.ENSDARP00000026466.

    Protein family/group databases

    MEROPSi M10.013.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    ZFINi ZDB-GENE-031202-2. mmp13a.

    Phylogenomic databases

    HOGENOMi HOG000217927.
    HOVERGENi HBG052484.
    InParanoidi Q71G59.

    Family and domain databases

    Gene3Di 2.110.10.10. 1 hit.
    3.40.390.10. 1 hit.
    InterProi IPR000585. Hemopexin-like_dom.
    IPR018487. Hemopexin-like_repeat.
    IPR018486. Hemopexin_CS.
    IPR024079. MetalloPept_cat_dom.
    IPR001818. Pept_M10_metallopeptidase.
    IPR021190. Pept_M10A.
    IPR016293. Pept_M10A_stromelysin-type.
    IPR021158. Pept_M10A_Zn_BS.
    IPR006026. Peptidase_Metallo.
    IPR002477. Peptidoglycan-bd-like.
    [Graphical view ]
    Pfami PF00045. Hemopexin. 3 hits.
    PF00413. Peptidase_M10. 1 hit.
    PF01471. PG_binding_1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001191. Peptidase_M10A_matrix. 1 hit.
    PRINTSi PR00138. MATRIXIN.
    SMARTi SM00120. HX. 4 hits.
    SM00235. ZnMc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47090. SSF47090. 1 hit.
    SSF50923. SSF50923. 1 hit.
    PROSITEi PS00546. CYSTEINE_SWITCH. 1 hit.
    PS00024. HEMOPEXIN. 1 hit.
    PS51642. HEMOPEXIN_2. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and Functional Analysis of Zebrafish MMP13."
      Bai S., Sarras M.P.Jr.
      Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ71G59_DANRE
    AccessioniPrimary (citable) accession number: Q71G59
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)