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Q712N7 (Q712N7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Caveolin RuleBase RU000680
Gene names
Name:caveolin-2 EMBL CAB36907.1
OrganismHomo sapiens (Human) EMBL CAB36907.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length21 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Function

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity By similarity. RuleBase RU000680

Subcellular location

Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membranecaveola; Peripheral membrane protein By similarity RuleBase RU000680.

Sequence similarities

Belongs to the caveolin family. RuleBase RU000680

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL CAB36907.1
Non-terminal residue211 EMBL CAB36907.1

Sequences

Sequence LengthMass (Da)Tools
Q712N7 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 4AC6FC4BB5C265E4

FASTA212,373
        10         20 
PHRLNSHLKL GFEDVIAEPV T 

« Hide

References

[1]"Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors."
Fra A.M., Mastroianni N., Mancini M., Pasqualetto E., Sitia R.
Genomics 56:355-356(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ011300 Genomic DNA. Translation: CAB36907.1.
UniGeneHs.212332.
Hs.603096.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOGENOMHOG000036550.

Gene expression databases

ArrayExpressQ712N7.
BgeeQ712N7.

Family and domain databases

InterProIPR001612. Caveolin.
IPR018361. Caveolin_CS.
[Graphical view]
PfamPF01146. Caveolin. 1 hit.
[Graphical view]
PROSITEPS01210. CAVEOLIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ712N7_HUMAN
AccessionPrimary (citable) accession number: Q712N7
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.