Reviewed, UniProtKB/Swiss-Prot Q711G1 (G6PI_AGABI)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:

gpi1

Organism

Agaricus bisporus (Common mushroom)

Taxonomic identifier

5341 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Homobasidiomycetes › Agaricomycetidae › Agaricales › Agaricaceae › Agaricus

Protein attributes

Sequence length	551 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate.
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 551	551	Glucose-6-phosphate isomerase		PRO_0000180569
Sites
	Active site	360	1	Proton donor By similarity
	Active site	391	1	By similarity
	Active site	516	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q711G1-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 3747B1A074021671	FASTA	551	61,446
	10 20 30 40 50 60 MTGSLASNYA SWKQLQEIYD KDRAKIVLRD LFAADPQRFS KLSATYNSQS GPGVQILLDY 70 80 90 100 110 120 SKHLVTEPIL QKLFNLLREA KVEDARDKMF SGEHINTSED RAVLHVALRN FNDFSIKEEG 130 140 150 160 170 180 VDEVSKVLQH MKEFSESVRS GQWKGYTGKT INTIVNIGIG GSDLGPVMVT EALKPFSKRD 190 200 210 220 230 240 LNAHFVSNID GTHIAETLRL CDPERTLFIV ASKTFTTQET ITNAESARDW FLGFAKDKAH 250 260 270 280 290 300 VAKHFVALST NTSAVTAFGI SEANMFQFWD WVGGRYSLWS AIGLSIALVI GFDNFEKLLR 310 320 330 340 350 360 GAHAMDQHFK TTPLEKNLPA IMAALGIWCN DFYGAQTLAL LPYDQYLHKF ADYFQQGDME 370 380 390 400 410 420 SNGKFITKNG DRVNYQTGPI IWGASGTNGQ HSFYQLIHQG TKIIPADFMA PATSHNPIAN 430 440 450 460 470 480 SKHHRILLSN FFAQPEALAF GKTEEEVRKE LGQNASEALV KSKVFEGNRP SSSLMFDKLD 490 500 510 520 530 540 PATLGALIAL YEHKIFVQGV VWGINSFDQM GVELGKVLAK QILAQLDKSD DVKGHDSSVR 550 HLPFILQVDH C

References

[1]	"Characterisation of a senescence locus in Agaricus bisporus." Kingsnorth C.S., Woodhouse C.S., Henderson J., Burton K.S. Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ345056 Genomic DNA. Translation: CAC87889.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.3.1.9. 984.
Family and domain databases
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_AGABI

Accession

Primary (citable) accession number: Q711G1

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2004
Last sequence update:	July 5, 2004
Last modified:	October 13, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)