ID   Q71057_9HIV1            Unreviewed;       350 AA.
AC   Q71057;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   24-JAN-2024, entry version 83.
DE   SubName: Full=Envelope glycoprotein {ECO:0000313|EMBL:AAA86065.1};
DE   Flags: Fragment;
GN   Name=env {ECO:0000313|EMBL:AAA86065.1};
OS   Human immunodeficiency virus 1.
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=11676 {ECO:0000313|EMBL:AAA86065.1};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1] {ECO:0000313|EMBL:AAA86065.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Brain {ECO:0000313|EMBL:AAA86065.1};
RA   Xin K.-Q., Shapshak P., Nagano I., Stewart R.V., Srivastava A.K., Wood C.,
RA   Morikawa S., Ushijima H., Okuda K.;
RT   "Heteogeneity of V1-V5 regions of the HIV-1 envelope gene from brain,
RT   cerebrospinal fluid, and blood from patients with AIDS.";
RL   Submitted (OCT-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAA86065.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Brain {ECO:0000313|EMBL:AAA86065.1};
RX   PubMed=7668155;
RA   Shapshak P., Nagano I., Xin K., Bradley W., McCoy C.B., Sun N.C.J.,
RA   Stewart R.V., Yoshioka M., Petito C., Goodkin K., Douyon R.,
RA   Srivastava A.K., Crandall K.A.;
RT   "HIV-1 heterogeneity and cytokines. Neuropathogenesis.";
RL   Adv. Exp. Med. Biol. 373:225-238(1995).
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DR   EMBL; U16059; AAA86065.1; -; mRNA.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   Gene3D; 2.170.40.20; Human immunodeficiency virus 1, Gp160, envelope glycoprotein; 1.
DR   InterPro; IPR036377; Gp120_core_sf.
DR   InterPro; IPR000777; HIV1_Gp120.
DR   Pfam; PF00516; GP120; 1.
DR   SUPFAM; SSF56502; gp120 core; 1.
PE   2: Evidence at transcript level;
KW   Viral envelope protein {ECO:0000313|EMBL:AAA86065.1};
KW   Virion {ECO:0000313|EMBL:AAA86065.1}.
FT   DOMAIN          1..350
FT                   /note="Human immunodeficiency virus 1 envelope glycoprotein
FT                   Gp120"
FT                   /evidence="ECO:0000259|Pfam:PF00516"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAA86065.1"
FT   NON_TER         350
FT                   /evidence="ECO:0000313|EMBL:AAA86065.1"
SQ   SEQUENCE   350 AA;  38634 MW;  F7BA4A1C0C3CBBA1 CRC64;
     TPLCVSLKCT DLKNDTNTNS SSGRMIMEKG EIKNCSFNIS TSIRGKVQKE YAFFYKLDII
     PIDNDTTSYK LTSCNTSVIT QACPKVSFEP IPIHYCAPAG FAILKCNNKT FNGTGPCTNV
     STVQCTHGIR PVVSTQLLLN GSLAEEEVVI RSVNFTDNAK TIIVQLNTSV EINCTRPNNN
     TRKRIRIQRG PGRAFVTIGK IGSMRQAHCN ISRPRWNNTL RQIATRLREQ FGDNKTIIFN
     QSSGGNPDIV THSFNCGGEG FYCNSTHLFN STWHTSTWRA DGSNDTEGSD TITLPCRIKQ
     IINMWQKVGK AMYAPPISGQ IRCSSNITGL LLTRDGGNSN NESEIFRPGG
//