Q70VZ3 (Q70VZ3_CIOIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
FoxE EMBL CAD58963.1

Submitted name:
Uncharacterized protein Ensembl ENSCINP00000015355

Gene names

Name:

foxE Ensembl ENSCINP00000015355 EMBL CAD58963.1

Organism

Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) [Reference proteome]

Taxonomic identifier

7719 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Tunicata › Ascidiacea › Enterogona › Phlebobranchia › Cionidae › Ciona

Protein attributes

Sequence length	721 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 fork-head DNA-binding domain. SAAS SAAS018122

Ontologies

Keywords
Biological process	Transcription Transcription regulation SAAS SAAS001766
Cellular component	Nucleus SAAS SAAS001766
Ligand	DNA-binding SAAS SAAS018122
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell migration Inferred from Biological aspect of Ancestor. Source: RefGenome embryonic organ morphogenesis Inferred from Biological aspect of Ancestor. Source: RefGenome enteric nervous system development Inferred from Biological aspect of Ancestor. Source: RefGenome lateral line nerve glial cell development Inferred from Biological aspect of Ancestor. Source: RefGenome pattern specification process Inferred from Biological aspect of Ancestor. Source: RefGenome peripheral nervous system development Inferred from Biological aspect of Ancestor. Source: RefGenome positive regulation of transcription from RNA polymerase II promoter Inferred from Biological aspect of Ancestor. Source: RefGenome regulation of sequence-specific DNA binding transcription factor activity Inferred from Biological aspect of Ancestor. Source: RefGenome sympathetic nervous system development Inferred from Biological aspect of Ancestor. Source: RefGenome tissue development Inferred from Biological aspect of Ancestor. Source: RefGenome
Cellular_component	transcription factor complex Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular_function	DNA binding, bending Inferred from Biological aspect of Ancestor. Source: RefGenome RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Inferred from Biological aspect of Ancestor. Source: RefGenome double-stranded DNA binding Inferred from Biological aspect of Ancestor. Source: RefGenome sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor binding Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q70VZ3 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 0D17EE8BB8248B67	FASTA	721	80,498
	10 20 30 40 50 60 MDQKRAHNYS AAHHTTTYQD YQTFTNHCMN GYQPFIPNLS YCNAYNFGRD PSFDPFDDFG 70 80 90 100 110 120 IFRPTGDPSN LPTRTGCFTR TSLSVADDNQ GDGKIETISD PGVSILPCIK LPPLMLTSSS 130 140 150 160 170 180 AENSAENEEA VSGVDCSAPP KQGNDLSQQQ IHGVHHSSPH IHAKNPSNQR IPHDQPASFS 190 200 210 220 230 240 SNHRYSHYPI QPGHFEQGNP HSYLDRQYPN PSSYAPPVVK DASRNQQPFH STPTCEPPRS 250 260 270 280 290 300 EVAFTPCNPT YDELQRKDEA TQQFTDIGRT DLQTPAEVEQ TLLEIDDKVD LAESDETVTK 310 320 330 340 350 360 LSECSVDDVT AVDDESLDEK NRENVKTTMD CDVITTTSSG RRRKRPIQRG KPPYSYIALI 370 380 390 400 410 420 SMAIASSPER KLTLGHIYKF IMERFPFYRE QNKKWQNSIR HNLTLNDCFI KLPREPGKPG 430 440 450 460 470 480 KGNYWTLDPA AEDMFDNGSF LRRRKRFKRS DTEKAFLSSY MHDQSAFTPT NALKQYSTHP 490 500 510 520 530 540 HTPSNAYYGQ PGVVGGNYLQ PIMHPGSAGA PVHQMMGHYG APMTVSPNVT NARMFSIENI 550 560 570 580 590 600 IGHPRPNENL PPEVSEYSDN MRHDGLNSER DLLDREGTNN VDRSLQANTS SQSQPSPSSG 610 620 630 640 650 660 LYGAMTSPSV RGIICNNESV STCYAYHTPT TTNPHCYTGS TGSPYGVTSN QRLTSLPIKP 670 680 690 700 710 720 SYHSAFANPV HHYHSDVTNM TSLSTDFTSL QTPGQFNSLP SSTYRRPPAN YGGFDKYIHT I

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins." Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A., Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N., Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P., Martinez D. , Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S., Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K., Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P., Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S., Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G., Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A., Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M., Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D., Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F., Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N., Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M., Satoh N., Rokhsar D.S. Science 298:2157-2167(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Phylogenetic analysis of Ciona intestinalis gene superfamilies supports the hypothesis of gene expansion at the base of vertebrate ancestry." Leveugle M., Prat K., Popovici C., Birnbaum D., Coulier F. Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EAAA01002052 Genomic DNA. No translation available. AJ534401 mRNA. Translation: CAD58963.1.
RefSeq	NP_001027947.1. NM_001032775.1.
UniGene	Cin.14354.
3D structure databases
HSSP	HSSP built from PDB template 1JXS based on UniProtKB Q01167.
SMR	Q70VZ3. Positions 351-446.
ModBase	Search...
Protein-protein interaction databases
STRING	7719.ENSCINP00000015355.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSCINT00000015355; ENSCINP00000015355; ENSCING00000007489.
GeneID	445746.
KEGG	cin:445746.
Organism-specific databases
CTD	445746.
Phylogenomic databases
GeneTree	ENSGT00700000104135.
HOGENOM	HOG000169920.
HOVERGEN	HBG065789.
InParanoid	Q70VZ3.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
InterPro	IPR001766. TF_fork_head. IPR018122. TF_fork_head_CS. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF00250. Fork_head. 1 hit. [Graphical view]
PRINTS	PR00053. FORKHEAD.
SMART	SM00339. FH. 1 hit. [Graphical view]
PROSITE	PS00657. FORK_HEAD_1. 1 hit. PS00658. FORK_HEAD_2. 1 hit. PS50039. FORK_HEAD_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q70VZ3_CIOIN

Accession

Primary (citable) accession number: Q70VZ3
Secondary accession number(s): F6XWF9

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)