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Protein

Importin subunit alpha

Gene

imp alpha 5

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein transporter activity Source: InterPro

GO - Biological processi

  1. protein import into nucleus Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Protein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Importin subunit alphaUniRule annotation
Gene namesi
Name:imp alpha 5Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
  2. nucleus Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliQ70PC5.
SMRiQ70PC5. Positions 83-506.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the importin alpha family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG001846.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR002652. Importin-a_IBB.
IPR024931. Importing_su_alpha.
[Graphical view]
PfamiPF00514. Arm. 8 hits.
PF01749. IBB. 1 hit.
[Graphical view]
PIRSFiPIRSF005673. Importin_alpha. 1 hit.
SMARTiSM00185. ARM. 8 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 4 hits.
PS51214. IBB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q70PC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTMASPGKD NSRMKSYKNK ALNPEEMRRR REEEGIQLRK QKREQQLFKR
60 70 80 90 100
RNVELAPEDT AMFDGPLMDS HVSSTTPGDG VITREMVALL LSDDPDLQLA
110 120 130 140 150
TTQKFRKLLS KEPNPPIDEV INAPGVVERF VEFLKKSDNY TLQFEAAWAL
160 170 180 190 200
TNIASGTSQQ TKIVIEAGAV PIFIQLLNSD YEDVQEQAVW ALGNIAGDSS
210 220 230 240 250
VCRDYVLSCD ILPPLLNLLT KSTRLTMTRN AVWALSNLCR GKNPPPDFDK
260 270 280 290 300
VSPCLPVLSR LLFSSDSDLL ADACWALSYL SDGPNEKIQA VIDSGVCRRL
310 320 330 340 350
VELLMHNDYK VASPALRAVG NIVTGDDIQT QVILNCSALP CLLHLLSSPK
360 370 380 390 400
ESIRKEACWT ISNITAGNRG QIQVVADANI FPVLIEILQK AEFRTRKEAA
410 420 430 440 450
WAITNATSGG TPEQIRYLVN LGCIKPLCDL LTVMDSKIVQ VALNGLENIL
460 470 480 490 500
RLGEQEAKHG GNGINPYCGL IEEAYGLDKI EFLQSHENQE IYQKAFELIE
510 520 530
HYFGVEEDDP QLVPSVDESQ QQYIFQQTEA PMEGFQL
Length:537
Mass (Da):59,813
Last modified:July 5, 2004 - v1
Checksum:iDF492A7262DB6A30
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ557448 mRNA. Translation: CAD89699.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ557448 mRNA. Translation: CAD89699.1.

3D structure databases

ProteinModelPortaliQ70PC5.
SMRiQ70PC5. Positions 83-506.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG001846.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR002652. Importin-a_IBB.
IPR024931. Importing_su_alpha.
[Graphical view]
PfamiPF00514. Arm. 8 hits.
PF01749. IBB. 1 hit.
[Graphical view]
PIRSFiPIRSF005673. Importin_alpha. 1 hit.
SMARTiSM00185. ARM. 8 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 4 hits.
PS51214. IBB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Signals and receptors for the nuclear transport of TFIIIA in Xenopus oocytes."
    Wischnewski J., Rudt F., Pieler T.
    Eur. J. Cell Biol. 83:1-12(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Signals and receptors for the nuclear transport of TFIIIA in Xenopus oocytes."
    Wischnewski J., Rudt F., Pieler T.
    Eur. J. Cell Biol. 83:55-66(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ70PC5_XENLA
AccessioniPrimary (citable) accession number: Q70PC5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 1, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.