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Q709N3

- P19_PENSV

UniProt

Q709N3 - P19_PENSV

Protein

RNA silencing suppressor p19

Gene

ORF4

Organism
Pelargonium necrotic spot virus (PeNSV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA By similarity.By similarity

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Suppressor of RNA silencing

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA silencing suppressor p19
    Alternative name(s):
    19 kDa symptom severity modulator
    Gene namesi
    ORF Names:ORF4
    OrganismiPelargonium necrotic spot virus (PeNSV)
    Taxonomic identifieri255587 [NCBI]
    Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
    Virus hostiPelargonium peltatum [TaxID: 122192]
    Pelargonium zonale [TaxID: 4032]

    Subcellular locationi

    GO - Cellular componenti

    1. virion Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 172172RNA silencing suppressor p19PRO_0000222877Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ709N3.
    SMRiQ709N3. Positions 9-152.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tombusvirus protein p19 family.Curated

    Family and domain databases

    InterProiIPR004905. Tombusvirus_p19.
    [Graphical view]
    PfamiPF03220. Tombus_P19. 1 hit.
    [Graphical view]
    ProDomiPD005743. Tombus_P19. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF103145. SSF103145. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q709N3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERAVQGGDA REQANSERWD GGCGGTITPF KLSDESPSLH EWRLHHSEEG    50
    EDQDHPLGFK ESWSFGKVVF KRYLRYGGTE TSLHRALGSW ERNTVNNAAS 100
    RFLGFGQIGC TYSIRFRGSC LTISGGSRTL QRLIEMAIRT KCTVLQLTPS 150
    EVEGNVSGGS PEGIEAFEKE SE 172
    Length:172
    Mass (Da):19,060
    Last modified:July 5, 2004 - v1
    Checksum:iD420F64DDA2D2C55
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ607402 Genomic RNA. Translation: CAE55160.1.
    RefSeqiNP_945118.1. NC_005285.1.

    Genome annotation databases

    GeneIDi10216565.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ607402 Genomic RNA. Translation: CAE55160.1 .
    RefSeqi NP_945118.1. NC_005285.1.

    3D structure databases

    ProteinModelPortali Q709N3.
    SMRi Q709N3. Positions 9-152.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 10216565.

    Family and domain databases

    InterProi IPR004905. Tombusvirus_p19.
    [Graphical view ]
    Pfami PF03220. Tombus_P19. 1 hit.
    [Graphical view ]
    ProDomi PD005743. Tombus_P19. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF103145. SSF103145. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Pelargonium necrotic spot virus: a new member of the genus Tombusvirus."
      Heinze C., Wobbe V., Lesemann D.-E., Zhang D.Y., Willingmann P., Adam G.
      Arch. Virol. 149:1527-1539(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiP19_PENSV
    AccessioniPrimary (citable) accession number: Q709N3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 15, 2005
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3