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Q709N3

- P19_PENSV

UniProt

Q709N3 - P19_PENSV

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Protein

RNA silencing suppressor p19

Gene

ORF4

Organism
Pelargonium necrotic spot virus (PeNSV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Suppressor of RNA silencing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA silencing suppressor p19
Alternative name(s):
19 kDa symptom severity modulator
Gene namesi
ORF Names:ORF4
OrganismiPelargonium necrotic spot virus (PeNSV)
Taxonomic identifieri255587 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiPelargonium peltatum [TaxID: 122192]
Pelargonium zonale [TaxID: 4032]

Subcellular locationi

GO - Cellular componenti

  1. virion Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 172172RNA silencing suppressor p19PRO_0000222877Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ709N3.
SMRiQ709N3. Positions 9-152.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tombusvirus protein p19 family.Curated

Family and domain databases

InterProiIPR004905. Tombusvirus_p19.
[Graphical view]
PfamiPF03220. Tombus_P19. 1 hit.
[Graphical view]
ProDomiPD005743. Tombus_P19. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF103145. SSF103145. 1 hit.

Sequencei

Sequence statusi: Complete.

Q709N3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERAVQGGDA REQANSERWD GGCGGTITPF KLSDESPSLH EWRLHHSEEG
60 70 80 90 100
EDQDHPLGFK ESWSFGKVVF KRYLRYGGTE TSLHRALGSW ERNTVNNAAS
110 120 130 140 150
RFLGFGQIGC TYSIRFRGSC LTISGGSRTL QRLIEMAIRT KCTVLQLTPS
160 170
EVEGNVSGGS PEGIEAFEKE SE
Length:172
Mass (Da):19,060
Last modified:July 5, 2004 - v1
Checksum:iD420F64DDA2D2C55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ607402 Genomic RNA. Translation: CAE55160.1.
RefSeqiNP_945118.1. NC_005285.1.

Genome annotation databases

GeneIDi10216565.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ607402 Genomic RNA. Translation: CAE55160.1 .
RefSeqi NP_945118.1. NC_005285.1.

3D structure databases

ProteinModelPortali Q709N3.
SMRi Q709N3. Positions 9-152.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 10216565.

Family and domain databases

InterProi IPR004905. Tombusvirus_p19.
[Graphical view ]
Pfami PF03220. Tombus_P19. 1 hit.
[Graphical view ]
ProDomi PD005743. Tombus_P19. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF103145. SSF103145. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Pelargonium necrotic spot virus: a new member of the genus Tombusvirus."
    Heinze C., Wobbe V., Lesemann D.-E., Zhang D.Y., Willingmann P., Adam G.
    Arch. Virol. 149:1527-1539(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiP19_PENSV
AccessioniPrimary (citable) accession number: Q709N3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: July 5, 2004
Last modified: October 1, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3