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Q709C8

- VP13C_HUMAN

UniProt

Q709C8 - VP13C_HUMAN

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Protein
Vacuolar protein sorting-associated protein 13C
Gene
VPS13C, KIAA1421
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar protein sorting-associated protein 13C
Gene namesi
Name:VPS13C
Synonyms:KIAA1421
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 15

Organism-specific databases

HGNCiHGNC:23594. VPS13C.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: UniProt
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134990089.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 37533753Vacuolar protein sorting-associated protein 13C
PRO_0000262949Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei614 – 6141Phosphothreonine1 Publication
Modified residuei619 – 6191Phosphoserine1 Publication
Modified residuei624 – 6241Phosphothreonine1 Publication
Modified residuei737 – 7371Phosphoserine1 Publication
Modified residuei1979 – 19791Phosphoserine By similarity
Cross-linki2357 – 2357Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Modified residuei3538 – 35381N6-acetyllysine1 Publication

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQBiQ709C8.
PaxDbiQ709C8.
PRIDEiQ709C8.

PTM databases

PhosphoSiteiQ709C8.

Expressioni

Tissue specificityi

Widely expressed.1 Publication

Gene expression databases

ArrayExpressiQ709C8.
BgeeiQ709C8.
CleanExiHS_VPS13C.
GenevestigatoriQ709C8.

Organism-specific databases

HPAiHPA043356.
HPA043507.

Interactioni

Protein-protein interaction databases

BioGridi120186. 2 interactions.
IntActiQ709C8. 2 interactions.
STRINGi9606.ENSP00000261517.

Structurei

3D structure databases

ProteinModelPortaliQ709C8.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi145 – 17935Lys-rich
Add
BLAST

Sequence similaritiesi

Belongs to the VPS13 family.

Phylogenomic databases

eggNOGiCOG5043.
HOVERGENiHBG079736.
InParanoidiQ709C8.
OMAiTHIIETR.
OrthoDBiEOG7S4X52.
PhylomeDBiQ709C8.
TreeFamiTF300316.

Family and domain databases

InterProiIPR015412. Autophagy-rel_C.
IPR026847. VPS13.
IPR026854. VPS13A_N.
IPR009543. VPSAP_dom.
[Graphical view]
PANTHERiPTHR16166. PTHR16166. 1 hit.
PfamiPF09333. ATG_C. 1 hit.
PF12624. Chorein_N. 1 hit.
PF06650. DUF1162. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 11 Publication (identifier: Q709C8-1) [UniParc]FASTAAdd to Basket

Also known as: 2A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MVLESVVADL LNRFLGDYVE NLNKSQLKLG IWGGNVALDN LQIKENALSE     50
LDVPFKVKAG QIDKLTLKIP WKNLYGEAVV ATLEGLYLLV VPGASIKYDA 100
VKEEKSLQDV KQKELSRIEE ALQKAAEKGT HSGEFIYGLE NFVYKDIKPG 150
RKRKKHKKHF KKPFKGLDRS KDKPKEAKKD TFVEKLATQV IKNVQVKITD 200
IHIKYEDDVT DPKRPLSFGV TLGELSLLTA NEHWTPCILN EADKIIYKLI 250
RLDSLSAYWN VNCSMSYQRS REQILDQLKN EILTSGNIPP NYQYIFQPIS 300
ASAKLYMNPY AESELKTPKL DCNIEIQNIA IELTKPQYLS MIDLLESVDY 350
MVRNAPYRKY KPYLPLHTNG RRWWKYAIDS VLEVHIRRYT QMWSWSNIKK 400
HRQLLKSYKI AYKNKLTQSK VSEEIQKEIQ DLEKTLDVFN IILARQQAQV 450
EVIRSGQKLR KKSADTGEKR GGWFSGLWGK KESKKKDEES LIPETIDDLM 500
TPEEKDKLFT AIGYSESTHN LTLPKQYVAH IMTLKLVSTS VTIRENKNIP 550
EILKIQIIGL GTQVSQRPGA QALKVEAKLE HWYITGLRQQ DIVPSLVASI 600
GDTTSSLLKI KFETNPEDSP ADQTLIVQSQ PVEVIYDAKT VNAVVEFFQS 650
NKGLDLEQIT SATLMKLEEI KERTATGLTH IIETRKVLDL RINLKPSYLV 700
VPQTGFHHEK SDLLILDFGT FQLNSKDQGL QKTTNSSLEE IMDKAYDKFD 750
VEIKNVQLLF ARAEETWKKC RFQHPSTMHI LQPMDIHVEL AKAMVEKDIR 800
MARFKVSGGL PLMHVRISDQ KMKDVLYLMN SIPLPQKSSA QSPERQVSSI 850
PIISGGTKGL LGTSLLLDTV ESESDDEYFD AEDGEPQTCK SMKGSELKKA 900
AEVPNEELIN LLLKFEIKEV ILEFTKQQKE EDTILVFNVT QLGTEATMRT 950
FDLTVVSYLK KISLDYHEIE GSKRKPLHLI SSSDKPGLDL LKVEYIKADK 1000
NGPSFQTAFG KTEQTVKVAF SSLNLLLQTQ ALVASINYLT TIIPSDDQSI 1050
SVAKEVQIST EKQQKNSTLP KAIVSSRDSD IIDFRLFAKL NAFCVIVCNE 1100
KNNIAEIKIQ GLDSSLSLQS RKQSLFARLE NIIVTDVDPK TVHKKAVSIM 1150
GNEVFRFNLD LYPDATEGDL YTDMSKVDGV LSLNVGCIQI VYLHKFLMSL 1200
LNFLNNFQTA KESLSAATAQ AAERAATSVK DLAQRSFRVS INIDLKAPVI 1250
VIPQSSISTN AVVVDLGLIR VHNQFSLVSD EDYLNPPVID RMDVQLTKLT 1300
LYRTVIQPGI YHPDIQLLHP INLEFLVNRN LAASWYHKVP VVEIKGHLDS 1350
MNVSLNQEDL NLLFRILTEN LCEGTEDLDK VKPRVQETGE IKEPLEISIS 1400
QDVHDSKNTL TTGVEEIRSV DIINMLLNFE IKEVVVTLMK KSEKKGRPLH 1450
ELNVLQLGME AKVKTYDMTA KAYLKKISMQ CFDFTDSKGE PLHIINSSNV 1500
TDEPLLKMLL TKADSDGPEF KTIHDSTKQR LKVSFASLDL VLHLEALLSF 1550
MDFLSSAAPF SEPSSSEKES ELKPLVGESR SIAVKAVSSN ISQKDVFDLK 1600
ITAELNAFNV FVCDQKCNIA DIKIHGMDAS ISVKPKQTDV FARLKDIIVM 1650
NVDLQSIHKK AVSILGDEVF RFQLTLYPDA TEGEAYADMS KVDGKLSFKV 1700
GCIQIVYVHK FFMSLLNFLN NFQTAKEALS TATVQAAERA ASSMKDLAQK 1750
SFRLLMDINL KAPVIIIPQS SVSPNAVIAD LGLIRVENKF SLVPMEHYSL 1800
PPVIDKMNIE LTQLKLSRTI LQASLPQNDI EILKPVNMLL SIQRNLAAAW 1850
YVQIPGMEIK GKLKPMQVAL SEDDLTVLMK ILLENLGEAS SQPSPTQSVQ 1900
ETVRVRKVDV SSVPDHLKEQ EDWTDSKLSM NQIVSLQFDF HFESLSIILY 1950
NNDINQESGV AFHNDSFQLG ELRLHLMASS GKMFKDGSMN VSVKLKTCTL 2000
DDLREGIERA TSRMIDRKND QDNNSSMIDI SYKQDKNGSQ IDAVLDKLYV 2050
CASVEFLMTV ADFFIKAVPQ SPENVAKETQ ILPRQTATGK VKIEKDDSVR 2100
PNMTLKAMIT DPEVVFVASL TKADAPALTA SFQCNLSLST SKLEQMMEAS 2150
VRDLKVLACP FLREKRGKNI TTVLQPCSLF MEKCTWASGK QNINIMVKEF 2200
IIKISPIILN TVLTIMAALS PKTKEDGSKD TSKEMENLWG IKSINDYNTW 2250
FLGVDTATEI TESFKGIEHS LIEENCGVVV ESIQVTLECG LGHRTVPLLL 2300
AESKFSGNIK NWTSLMAAVA DVTLQVHYYN EIHAVWEPLI ERVEGKRQWN 2350
LRLDVKKNPV QDKSLLPGDD FIPEPQMAIH ISSGNTMNIT ISKSCLNVFN 2400
NLAKGFSEGT ASTFDYSLKD RAPFTVKNAV GVPIKVKPNC NLRVMGFPEK 2450
SDIFDVDAGQ NLELEYASMV PSSQGNLSIL SRQESSFFTL TIVPHGYTEV 2500
ANIPVARPGR RLYNVRNPNA SHSDSVLVQI DATEGNKVIT LRSPLQIKNH 2550
FSIAFIIYKF VKNVKLLERI GIARPEEEFH VPLDSYRCQL FIQPAGILEH 2600
QYKESTTYIS WKEELHRSRE VRCMLQCPSV EVSFLPLIVN TVALPDELSY 2650
ICTHGEDWDV AYIIHLYPSL TLRNLLPYSL RYLLEGTAET HELAEGSTAD 2700
VLHSRISGEI MELVLVKYQG KNWNGHFRIR DTLPEFFPVC FSSDSTEVTT 2750
VDLSVHVRRI GSRMVLSVFS PYWLINKTTR VLQYRSEDIH VKHPADFRDI 2800
ILFSFKKKNI FTKNKVQLKI STSAWSSSFS LDTVGSYGCV KCPANNMEYL 2850
VGVSIKMSSF NLSRIVTLTP FCTIANKSSL ELEVGEIASD GSMPTNKWNY 2900
IASSECLPFW PESLSGKLCV RVVGCEGSSK PFFYNRQDNG TLLSLEDLNG 2950
GILVDVNTAE HSTVITFSDY HEGSAPALIM NHTPWDILTY KQSGSPEEMV 3000
LLPRQARLFA WADPTGTRKL TWTYAANVGE HDLLKDGCGQ FPYDANIQIH 3050
WVSFLDGRQR VLLFTDDVAL VSKALQAEEM EQADYEITLS LHSLGLSLVN 3100
NESKQEVSYI GITSSGVVWE VKPKQKWKPF SQKQIILLEQ SYQKHQISRD 3150
HGWIKLDNNF EVNFDKDPME MRLPIRSPIK RDFLSGIQIE FKQSSHQRSL 3200
RARLYWLQVD NQLPGAMFPV VFHPVAPPKS IALDSEPKPF IDVSVITRFN 3250
EYSKVLQFKY FMVLIQEMAL KIDQGFLGAI IALFTPTTDP EAERRRTKLI 3300
QQDIDALNAE LMETSMTDMS ILSFFEHFHI SPVKLHLSLS LGSGGEESDK 3350
EKQEMFAVHS VNLLLKSIGA TLTDVDDLIF KLAYYEIRYQ FYKRDQLIWS 3400
VVRHYSEQFL KQMYVLVLGL DVLGNPFGLI RGLSEGVEAL FYEPFQGAVQ 3450
GPEEFAEGLV IGVRSLFGHT VGGAAGVVSR ITGSVGKGLA AITMDKEYQQ 3500
KRREELSRQP RDFGDSLARG GKGFLRGVVG GVTGIITKPV EGAKKEGAAG 3550
FFKGIGKGLV GAVARPTGGI VDMASSTFQG IQRAAESTEE VSSLRPPRLI 3600
HEDGIIRPYD RQESEGSDLL ENHIKKLEGE TYRYHCAIPG SKKTILMVTN 3650
RRVLCIKEVE ILGLMCVDWQ CPFEDFVFPP SVSENVLKIS VKEQGLFHKK 3700
DSANQGCVRK VYLKDTATAE RACNAIEDAQ STRQQQKLMK QSSVRLLRPQ 3750
LPS 3753
Length:3,753
Mass (Da):422,390
Last modified:July 5, 2004 - v1
Checksum:i8B51A6778A89F639
GO
Isoform 21 Publication (identifier: Q709C8-2) [UniParc]FASTAAdd to Basket

Also known as: 2B

The sequence of this isoform differs from the canonical sequence as follows:
     3622-3627: NHIKKL → QELEIQE
     3628-3753: Missing.

Show »
Length:3,628
Mass (Da):408,198
Checksum:i23C6AE1C69EEB060
GO
Isoform 31 Publication (identifier: Q709C8-3) [UniParc]FASTAAdd to Basket

Also known as: 1A

The sequence of this isoform differs from the canonical sequence as follows:
     129-171: Missing.

Show »
Length:3,710
Mass (Da):417,276
Checksum:i80E0633970F14F4B
GO
Isoform 41 Publication (identifier: Q709C8-4) [UniParc]FASTAAdd to Basket

Also known as: 1B

The sequence of this isoform differs from the canonical sequence as follows:
     129-171: Missing.
     3622-3627: NHIKKL → QELEIQE
     3628-3753: Missing.

Show »
Length:3,585
Mass (Da):403,084
Checksum:i433756079CA119A0
GO

Sequence cautioni

The sequence BAA90972.1 differs from that shown. Reason: Erroneous initiation.
The sequence BAA92659.1 differs from that shown. Reason: Erroneous initiation.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti153 – 1531R → H.
Corresponds to variant rs12595158 [ dbSNP | Ensembl ].
VAR_029548
Natural varianti974 – 9741R → K.1 Publication
Corresponds to variant rs3784634 [ dbSNP | Ensembl ].
VAR_029549
Natural varianti1132 – 11321I → V.
Corresponds to variant rs3784635 [ dbSNP | Ensembl ].
VAR_029550
Natural varianti1302 – 13021Y → C.
Corresponds to variant rs2303405 [ dbSNP | Ensembl ].
VAR_029551
Natural varianti1485 – 14851T → A.
Corresponds to variant rs8026956 [ dbSNP | Ensembl ].
VAR_029552
Natural varianti1495 – 14951I → V.
Corresponds to variant rs11629598 [ dbSNP | Ensembl ].
VAR_029553
Natural varianti1592 – 15921S → Y.
Corresponds to variant rs11629838 [ dbSNP | Ensembl ].
VAR_029554
Natural varianti2322 – 23221V → M.
Corresponds to variant rs12907567 [ dbSNP | Ensembl ].
VAR_029555
Natural varianti2808 – 28081K → R.
Corresponds to variant rs34060567 [ dbSNP | Ensembl ].
VAR_053808
Natural varianti2913 – 29131S → N.
Corresponds to variant rs10851704 [ dbSNP | Ensembl ].
VAR_029556

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei129 – 17143Missing in isoform 3 and isoform 4. 1 Publication
VSP_052243Add
BLAST
Alternative sequencei3622 – 36276NHIKKL → QELEIQE in isoform 2 and isoform 4. 1 Publication
VSP_052244
Alternative sequencei3628 – 3753126Missing in isoform 2 and isoform 4. 1 Publication
VSP_052245Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ608770 mRNA. Translation: CAE75582.1.
AJ608771 mRNA. Translation: CAE75583.1.
AJ626860 mRNA. Translation: CAF25187.1.
AJ626861 mRNA. Translation: CAF25188.1.
AB037842 mRNA. Translation: BAA92659.1. Different initiation.
AK000143 mRNA. Translation: BAA90972.1. Different initiation.
BC069387 mRNA. Translation: AAH69387.1.
CCDSiCCDS10180.1. [Q709C8-3]
CCDS32257.1. [Q709C8-1]
CCDS45272.1. [Q709C8-2]
CCDS58367.1. [Q709C8-4]
RefSeqiNP_001018098.1. NM_001018088.2. [Q709C8-2]
NP_060154.3. NM_017684.4. [Q709C8-3]
NP_060550.2. NM_018080.3. [Q709C8-4]
NP_065872.1. NM_020821.2. [Q709C8-1]
UniGeneiHs.511668.

Genome annotation databases

EnsembliENST00000249837; ENSP00000249837; ENSG00000129003. [Q709C8-3]
ENST00000261517; ENSP00000261517; ENSG00000129003. [Q709C8-1]
ENST00000395896; ENSP00000379233; ENSG00000129003. [Q709C8-2]
ENST00000395898; ENSP00000379235; ENSG00000129003. [Q709C8-4]
GeneIDi54832.
KEGGihsa:54832.
UCSCiuc002agz.3. human. [Q709C8-1]
uc002aha.3. human. [Q709C8-3]
uc002ahb.2. human. [Q709C8-2]
uc002ahc.2. human. [Q709C8-4]

Polymorphism databases

DMDMi74712594.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ608770 mRNA. Translation: CAE75582.1 .
AJ608771 mRNA. Translation: CAE75583.1 .
AJ626860 mRNA. Translation: CAF25187.1 .
AJ626861 mRNA. Translation: CAF25188.1 .
AB037842 mRNA. Translation: BAA92659.1 . Different initiation.
AK000143 mRNA. Translation: BAA90972.1 . Different initiation.
BC069387 mRNA. Translation: AAH69387.1 .
CCDSi CCDS10180.1. [Q709C8-3 ]
CCDS32257.1. [Q709C8-1 ]
CCDS45272.1. [Q709C8-2 ]
CCDS58367.1. [Q709C8-4 ]
RefSeqi NP_001018098.1. NM_001018088.2. [Q709C8-2 ]
NP_060154.3. NM_017684.4. [Q709C8-3 ]
NP_060550.2. NM_018080.3. [Q709C8-4 ]
NP_065872.1. NM_020821.2. [Q709C8-1 ]
UniGenei Hs.511668.

3D structure databases

ProteinModelPortali Q709C8.
ModBasei Search...

Protein-protein interaction databases

BioGridi 120186. 2 interactions.
IntActi Q709C8. 2 interactions.
STRINGi 9606.ENSP00000261517.

PTM databases

PhosphoSitei Q709C8.

Polymorphism databases

DMDMi 74712594.

Proteomic databases

MaxQBi Q709C8.
PaxDbi Q709C8.
PRIDEi Q709C8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000249837 ; ENSP00000249837 ; ENSG00000129003 . [Q709C8-3 ]
ENST00000261517 ; ENSP00000261517 ; ENSG00000129003 . [Q709C8-1 ]
ENST00000395896 ; ENSP00000379233 ; ENSG00000129003 . [Q709C8-2 ]
ENST00000395898 ; ENSP00000379235 ; ENSG00000129003 . [Q709C8-4 ]
GeneIDi 54832.
KEGGi hsa:54832.
UCSCi uc002agz.3. human. [Q709C8-1 ]
uc002aha.3. human. [Q709C8-3 ]
uc002ahb.2. human. [Q709C8-2 ]
uc002ahc.2. human. [Q709C8-4 ]

Organism-specific databases

CTDi 54832.
GeneCardsi GC15M062144.
HGNCi HGNC:23594. VPS13C.
HPAi HPA043356.
HPA043507.
MIMi 608879. gene.
neXtProti NX_Q709C8.
PharmGKBi PA134990089.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5043.
HOVERGENi HBG079736.
InParanoidi Q709C8.
OMAi THIIETR.
OrthoDBi EOG7S4X52.
PhylomeDBi Q709C8.
TreeFami TF300316.

Miscellaneous databases

ChiTaRSi VPS13C. human.
GenomeRNAii 54832.
NextBioi 57616.
PROi Q709C8.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q709C8.
Bgeei Q709C8.
CleanExi HS_VPS13C.
Genevestigatori Q709C8.

Family and domain databases

InterProi IPR015412. Autophagy-rel_C.
IPR026847. VPS13.
IPR026854. VPS13A_N.
IPR009543. VPSAP_dom.
[Graphical view ]
PANTHERi PTHR16166. PTHR16166. 1 hit.
Pfami PF09333. ATG_C. 1 hit.
PF12624. Chorein_N. 1 hit.
PF06650. DUF1162. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4), TISSUE SPECIFICITY.
    Tissue: Lymphoblast.
  2. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
    DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1439 (ISOFORMS 1/2), VARIANT LYS-974.
    Tissue: Brain.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3305-3753 (ISOFORMS 1/3).
    Tissue: Colon.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3305-3753 (ISOFORMS 1/3).
  5. "Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry."
    Denis N.J., Vasilescu J., Lambert J.-P., Smith J.C., Figeys D.
    Proteomics 7:868-874(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-2357.
    Tissue: Mammary cancer.
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-614; SER-619; THR-624 AND SER-737, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  8. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-3538, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  10. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiVP13C_HUMAN
AccessioniPrimary (citable) accession number: Q709C8
Secondary accession number(s): Q6ISR4
, Q702P2, Q702P3, Q709C9, Q9NXN8, Q9P2C6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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