Q708J1 (Q708J1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cyclin-dependent kinase inhibitor 1B EMBL CAE82383.1

Gene names

Name:

CDKN1B EMBL CAE82383.1

Organism

Homo sapiens (Human) EMBL CAE82383.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	136 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Cyclin EMBL CAE82383.1 Kinase EMBL CAE82383.1 Transferase
Gene Ontology (GO)
Biological_process	cell cycle arrest Inferred from electronic annotation. Source: InterPro
Cellular_component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular_function	cyclin-dependent protein serine/threonine kinase inhibitor activity Inferred from electronic annotation. Source: InterPro kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAE82383.1
	Non-terminal residue	136	1	EMBL CAE82383.1

Sequences

	Sequence		Length	Mass (Da)
	Q708J1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 079CD4EF67F6BB18	FASTA	136	15,322
	10 20 30 40 50 60 NVRVSNGSPS LERMDARQAE HPKPSACRNL FGPVDHEELT RDLEKHCRDM EEASQRKWNF 70 80 90 100 110 120 DFQNHKPLEG KYEWQEVEKG SLPEFYYRPP RPPKGACKVP AQESQDGSGS RPAAPLTGAP 130 ANSEDTHLVD PKTDPS

References

[1]	"A new point mutation in p27 gene in a patient with unclassified myeloproliferative syndrome." Papageorgiou S., Pappa V., Papageoregiou E., Economopoulos T., Kontsioti F., Dervenoulas J., Raptis S.A. Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Bone marrow EMBL CAE82383.1.
[2]	"Identification of point mutations in p16 and p27 genes in de novo myelodysplastic syndromes." Papageorgiou S. Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Bone marrow EMBL CAE82383.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ616234 mRNA. Translation: CAE82383.1.
IPI	IPI01011627.
UniGene	Hs.238990.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q708J1.
Proteomic databases
PRIDE	Q708J1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG073988.
Gene expression databases
ArrayExpress	Q708J1.
Family and domain databases
InterPro	IPR003175. CDI. [Graphical view]
PANTHER	PTHR10265. PTHR10265. 1 hit.
Pfam	PF02234. CDI. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	CDKN1B. human.

Entry information

Entry name

Q708J1_HUMAN

Accession

Primary (citable) accession number: Q708J1

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.