ID   Q708J0_HUMAN            Unreviewed;       678 AA.
AC   Q708J0;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 102.
DE   SubName: Full=V-myb myeloblastosis viral oncogene homologue (Avian) {ECO:0000313|EMBL:CAE82649.1};
DE   Flags: Fragment;
GN   Name=c-myb {ECO:0000313|EMBL:CAE82649.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:CAE82649.1};
RN   [1] {ECO:0000313|EMBL:CAE82649.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Close J.P., Game L., Clark B., Berginoux J., Gerovassili A., Thein S.;
RT   "Genome annotation and mutation analysis of a 1.5Mb region of 6q23
RT   encompassing a Quantitative Trait Locus for foetal haemoglobin
RT   expression.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; AJ616235; CAE82649.1; -; mRNA.
DR   AlphaFoldDB; Q708J0; -.
DR   SMR; Q708J0; -.
DR   PeptideAtlas; Q708J0; -.
DR   ChiTaRS; MYB; human.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00167; SANT; 3.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 3.
DR   InterPro; IPR015395; C-myb_C.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017930; Myb_dom.
DR   InterPro; IPR001005; SANT/Myb.
DR   InterPro; IPR012642; Tscrpt_reg_Wos2-domain.
DR   PANTHER; PTHR45614; MYB PROTEIN-RELATED; 1.
DR   PANTHER; PTHR45614:SF296; MYB-LIKE DNA-BINDING DOMAIN CONTAINING PROTEIN; 1.
DR   Pfam; PF09316; Cmyb_C; 1.
DR   Pfam; PF07988; LMSTEN; 1.
DR   Pfam; PF00249; Myb_DNA-binding; 3.
DR   SMART; SM00717; SANT; 3.
DR   SUPFAM; SSF46689; Homeodomain-like; 2.
DR   PROSITE; PS51294; HTH_MYB; 3.
DR   PROSITE; PS50090; MYB_LIKE; 3.
PE   2: Evidence at transcript level;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT   DOMAIN          73..124
FT                   /note="HTH myb-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51294"
FT   DOMAIN          73..124
FT                   /note="Myb-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50090"
FT   DOMAIN          125..180
FT                   /note="HTH myb-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51294"
FT   DOMAIN          125..176
FT                   /note="Myb-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50090"
FT   DOMAIN          177..227
FT                   /note="Myb-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50090"
FT   DOMAIN          181..231
FT                   /note="HTH myb-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51294"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          374..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAE82649.1"
SQ   SEQUENCE   678 AA;  76148 MW;  B8A85FBC6855F269 CRC64;
     GGSALPTPGR DAGRRRAAGG GSPVRSPRLS AEPRARRAMA RRPRHSIYSS DEDDEDFEMC
     DHDYDGLLPK SGKRHLGKTR WTREEDEKLK KLVEQNGTDD WKVIANYLPN RTDVQCQHRW
     QKVLNPELIK GPWTKEEDQR VIELVQKYGP KRWSVIAKHL KGRIGKQCRE RWHNHLNPEV
     KKTSWTEEED RIIYQAHKRL GNRWAEIAKL LPGRTDNAIK NHWNSTMRRK VEQEGYLQES
     SKASQPAVAT SFQKNSHLMG FAQAPPTAQL PATGQPTVNN DYSYYHISEA QNVSSHVPYP
     VALHVNIVNV PQPAAAAIQR HYNDEDPEKE KRIKELELLL MSTENELKGQ QVLPTQNHTC
     SYPGWHSTTI ADHTRPHGDS APVSCLGEHH STPSLPADPG SLPEESASPA RCMIVHQGTI
     LDNVKNLLEF AETLQFIDSF LNTSSNHENS DLEMPSLTST PLIGHKLTVT TPFHRDQTVK
     TQKENTVFRT PAIKRSILES SPRTPTPFKH ALAAQEIKYG PLKMLPQTPS HLVEDLQDVI
     KQESDESGIV AEFQENGPPL LKKIKQEVES PTDKSGNFFC SHHWEGDSLN TQLFTQTSPV
     ADAPNILTSS VLMAPASEDE DNVLKAFTVP KNRSLASPLQ PCSSTWEPAS CGKMEEQMTS
     SSQARKYVNA FSARTLVM
//