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Protein

Nucleoprotein

Gene

NP

Organism
Influenza A virus (A/England/939/69 x A/PR/8/34)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoproteinUniRule annotationSAAS annotation, RNA-bindingUniRule annotationSAAS annotation, Viral nucleoproteinUniRule annotationImported
Biological processHost-virus interactionUniRule annotationSAAS annotation, Viral penetration into host nucleusUniRule annotationSAAS annotation, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
NucleoproteinUniRule annotation
Alternative name(s):
Nucleocapsid proteinUniRule annotation
Short name:
Protein NUniRule annotation
Gene namesi
Name:NPUniRule annotationImported
OrganismiInfluenza A virus (A/England/939/69 x A/PR/8/34)Imported
Taxonomic identifieri137578 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesOrthomyxoviridaeAlphainfluenzavirus

Subcellular locationi

  • Host nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Helical capsid proteinUniRule annotationSAAS annotation, Host nucleusUniRule annotationSAAS annotation, Virion

PTM / Processingi

Post-translational modificationi

Late in virus-infected cells, may be cleaved from a 56-kDa protein to a 53-kDa protein by a cellular caspase. This cleavage might be a marker for the onset of apoptosis in infected cells or have a specific function in virus host interaction.UniRule annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2FWOX-ray2.60P147-155[»]
ProteinModelPortaliQ701N7
SMRiQ701N7
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ701N7

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi1 – 18Unconventional nuclear localization signalUniRule annotationAdd BLAST18
Motifi198 – 216Bipartite nuclear localization signalUniRule annotationAdd BLAST19

Sequence similaritiesi

Belongs to the influenza viruses nucleoprotein family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_04070 INFV_NCAP, 1 hit
InterProiView protein in InterPro
IPR002141 Flu_NP
PfamiView protein in Pfam
PF00506 Flu_NP, 1 hit

Sequencei

Sequence statusi: Complete.

Q701N7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASQGTKRSY EQMETDGERQ NATEIRASVG KMIDGIGRFY IQMCTELKLS
60 70 80 90 100
DYEGRLIQNS LTIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPIYKRV
110 120 130 140 150
DGKWMRELVL YDKEEIRRIW RQANNGDDAT AGLTHMMIWH SNLNDTTYQR
160 170 180 190 200
TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTMV MELIRMIKRG
210 220 230 240 250
INDRNFWRGE NGRKTRSAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN
260 270 280 290 300
AEIEDLIFLA RSALILRGSV AHKSCLPACV YGPAVASGYD FEKEGYSLVG
310 320 330 340 350
IDPFKLLQNS QVYSLIRPNE NPAHKSQLVW MACNSAAFED LRVLSFIRGT
360 370 380 390 400
KVSPRGKLST RGVQIASNEN MDTMESSTLE LRSRYWAIRT RSGGNTNQQR
410 420 430 440 450
ASAGQISVQP AFSVQRNLPF DKPTIMAAFT GNTEGRTSDM RAEIIRMMEG
460 470 480 490
AKPEEMSFQG RGVFELSDER AANPIVPSFD MSNEGSYFFG DNAEEYDN
Length:498
Mass (Da):56,084
Last modified:July 5, 2004 - v1
Checksum:iF0AA8337FF248CD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ628067 Genomic RNA Translation: CAF31360.1

Similar proteinsi

Entry informationi

Entry nameiQ701N7_9INFA
AccessioniPrimary (citable) accession number: Q701N7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 25, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health