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Q700K0 (SSPO_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
SCO-spondin
Gene names
Name:Sspo
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length5141 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Involved in the modulation of neuronal aggregation. May be involved in developmental events during the formation of the central nervous system By similarity.

Subcellular location

Secretedextracellular space By similarity.

Sequence similarities

Belongs to the thrombospondin family.

Contains 1 CTCK (C-terminal cystine knot-like) domain.

Contains 2 EGF-like domains.

Contains 1 EMI domain.

Contains 1 F5/8 type C domain.

Contains 10 LDL-receptor class A domains.

Contains 7 TIL (trypsin inhibitory-like) domains.

Contains 24 TSP type-1 domains.

Contains 2 VWFC domains.

Contains 3 VWFD domains.

Ontologies

Keywords
   Biological processCell adhesion
   Cellular componentSecreted
   DomainEGF-like domain
Repeat
Signal
   LigandCalcium
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcell adhesion

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: Ensembl

extracellular space

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 51415124SCO-spondin
PRO_0000245044

Regions

Domain18 – 10285EMI
Domain194 – 400207VWFD 1
Domain472 – 52756TIL 1
Domain566 – 776211VWFD 2
Domain830 – 88354TIL 2
Domain1018 – 1224207VWFD 3
Domain1280 – 133657TIL 3
Domain1380 – 141738LDL-receptor class A 1
Domain1420 – 145637LDL-receptor class A 2
Domain1456 – 149237LDL-receptor class A 3
Domain1496 – 153439LDL-receptor class A 4
Domain1569 – 160537LDL-receptor class A 5
Domain1607 – 164640LDL-receptor class A 6
Domain1660 – 170041LDL-receptor class A 7
Domain1699 – 175355TSP type-1 1
Domain1755 – 1970216TSP type-1 2
Domain1829 – 186840EGF-like 1
Domain1869 – 189527EGF-like 2
Domain1970 – 203061VWFC 1
Domain2070 – 2226157F5/8 type C
Domain2235 – 227137LDL-receptor class A 8
Domain2391 – 242737LDL-receptor class A 9
Domain2448 – 248437LDL-receptor class A 10
Domain2485 – 253854TSP type-1 3
Domain2540 – 259556TSP type-1 4
Domain2617 – 266044TIL 4
Domain2700 – 275455TSP type-1 5
Domain2758 – 281356TSP type-1 6
Domain2815 – 286854TSP type-1 7
Domain2969 – 302456TSP type-1 8
Domain3025 – 306844TSP type-1 9
Domain3075 – 312753TIL 5
Domain3168 – 323568TSP type-1 10
Domain3237 – 329256TSP type-1 11
Domain3303 – 335048TIL 6
Domain3393 – 345563TSP type-1 12
Domain3457 – 351256TSP type-1 13
Domain3630 – 367849TSP type-1 14
Domain3806 – 386257TSP type-1 15
Domain3876 – 392853TSP type-1 16
Domain3942 – 399857TSP type-1 17
Domain4000 – 405556TSP type-1 18
Domain4058 – 411356TIL 7
Domain4155 – 420854TSP type-1 19
Domain4249 – 430456TSP type-1 20
Domain4306 – 436257TSP type-1 21
Domain4364 – 441855TSP type-1 22
Domain4608 – 465952TSP type-1 23
Domain4759 – 481254TSP type-1 24
Domain4978 – 503659VWFC 2
Domain5047 – 513488CTCK
Compositional bias896 – 8994Poly-Thr

Amino acid modifications

Glycosylation881N-linked (GlcNAc...) Potential
Glycosylation1301N-linked (GlcNAc...) Potential
Glycosylation1501N-linked (GlcNAc...) Potential
Glycosylation1671N-linked (GlcNAc...) Potential
Glycosylation6571N-linked (GlcNAc...) Potential
Glycosylation8221N-linked (GlcNAc...) Potential
Glycosylation8951N-linked (GlcNAc...) Potential
Glycosylation9491N-linked (GlcNAc...) Potential
Glycosylation9911N-linked (GlcNAc...) Potential
Glycosylation13571N-linked (GlcNAc...) Potential
Glycosylation16551N-linked (GlcNAc...) Potential
Glycosylation16681N-linked (GlcNAc...) Potential
Glycosylation17251N-linked (GlcNAc...) Potential
Glycosylation18141N-linked (GlcNAc...) Potential
Glycosylation20351N-linked (GlcNAc...) Potential
Glycosylation21301N-linked (GlcNAc...) Potential
Glycosylation21481N-linked (GlcNAc...) Potential
Glycosylation26301N-linked (GlcNAc...) Potential
Glycosylation26791N-linked (GlcNAc...) Potential
Glycosylation29211N-linked (GlcNAc...) Potential
Glycosylation29511N-linked (GlcNAc...) Potential
Glycosylation30461N-linked (GlcNAc...) Potential
Glycosylation31011N-linked (GlcNAc...) Potential
Glycosylation31481N-linked (GlcNAc...) Potential
Glycosylation31581N-linked (GlcNAc...) Potential
Glycosylation32951N-linked (GlcNAc...) Potential
Glycosylation33841N-linked (GlcNAc...) Potential
Glycosylation35061N-linked (GlcNAc...) Potential
Glycosylation35841N-linked (GlcNAc...) Potential
Glycosylation36111N-linked (GlcNAc...) Potential
Glycosylation37871N-linked (GlcNAc...) Potential
Glycosylation39101N-linked (GlcNAc...) Potential
Glycosylation41351N-linked (GlcNAc...) Potential
Glycosylation43451N-linked (GlcNAc...) Potential
Glycosylation44161N-linked (GlcNAc...) Potential
Glycosylation45571N-linked (GlcNAc...) Potential
Glycosylation47271N-linked (GlcNAc...) Potential
Glycosylation47441N-linked (GlcNAc...) Potential
Glycosylation47491N-linked (GlcNAc...) Potential
Glycosylation48991N-linked (GlcNAc...) Potential
Glycosylation49421N-linked (GlcNAc...) Potential
Glycosylation49491N-linked (GlcNAc...) Potential
Glycosylation50551N-linked (GlcNAc...) Potential
Disulfide bond1381 ↔ 1394 By similarity
Disulfide bond1388 ↔ 1407 By similarity
Disulfide bond1401 ↔ 1416 By similarity
Disulfide bond1421 ↔ 1433 By similarity
Disulfide bond1428 ↔ 1446 By similarity
Disulfide bond1440 ↔ 1455 By similarity
Disulfide bond1457 ↔ 1469 By similarity
Disulfide bond1464 ↔ 1482 By similarity
Disulfide bond1476 ↔ 1491 By similarity
Disulfide bond1497 ↔ 1509 By similarity
Disulfide bond1504 ↔ 1522 By similarity
Disulfide bond1516 ↔ 1533 By similarity
Disulfide bond1570 ↔ 1582 By similarity
Disulfide bond1577 ↔ 1595 By similarity
Disulfide bond1589 ↔ 1604 By similarity
Disulfide bond1608 ↔ 1621 By similarity
Disulfide bond1615 ↔ 1634 By similarity
Disulfide bond1628 ↔ 1645 By similarity
Disulfide bond1661 ↔ 1671 By similarity
Disulfide bond1666 ↔ 1684 By similarity
Disulfide bond1678 ↔ 1699 By similarity
Disulfide bond1711 ↔ 1747 By similarity
Disulfide bond1715 ↔ 1752 By similarity
Disulfide bond1726 ↔ 1737 By similarity
Disulfide bond1767 ↔ 1964 By similarity
Disulfide bond1771 ↔ 1969 By similarity
Disulfide bond1781 ↔ 1791 By similarity
Disulfide bond2070 ↔ 2226 By similarity
Disulfide bond2236 ↔ 2248 By similarity
Disulfide bond2243 ↔ 2261 By similarity
Disulfide bond2255 ↔ 2270 By similarity
Disulfide bond2392 ↔ 2404 By similarity
Disulfide bond2399 ↔ 2417 By similarity
Disulfide bond2411 ↔ 2426 By similarity
Disulfide bond2449 ↔ 2461 By similarity
Disulfide bond2456 ↔ 2474 By similarity
Disulfide bond2468 ↔ 2483 By similarity
Disulfide bond2486 ↔ 2522 By similarity
Disulfide bond2497 ↔ 2501 By similarity
Disulfide bond2532 ↔ 2537 By similarity
Disulfide bond2552 ↔ 2589 By similarity
Disulfide bond2556 ↔ 2594 By similarity
Disulfide bond2567 ↔ 2579 By similarity
Disulfide bond2701 ↔ 2739 By similarity
Disulfide bond2712 ↔ 2716 By similarity
Disulfide bond2749 ↔ 2753 By similarity
Disulfide bond2769 ↔ 2807 By similarity
Disulfide bond2773 ↔ 2812 By similarity
Disulfide bond2789 ↔ 2797 By similarity
Disulfide bond2827 ↔ 2862 By similarity
Disulfide bond2831 ↔ 2867 By similarity
Disulfide bond2842 ↔ 2852 By similarity
Disulfide bond2970 ↔ 3008 By similarity
Disulfide bond2981 ↔ 2985 By similarity
Disulfide bond3018 ↔ 3023 By similarity
Disulfide bond3180 ↔ 3229 By similarity
Disulfide bond3184 ↔ 3234 By similarity
Disulfide bond3195 ↔ 3219 By similarity
Disulfide bond3249 ↔ 3286 By similarity
Disulfide bond3253 ↔ 3291 By similarity
Disulfide bond3264 ↔ 3276 By similarity
Disulfide bond3405 ↔ 3448 By similarity
Disulfide bond3409 ↔ 3454 By similarity
Disulfide bond3420 ↔ 3432 By similarity
Disulfide bond3469 ↔ 3504 By similarity
Disulfide bond3472 ↔ 3511 By similarity
Disulfide bond3482 ↔ 3494 By similarity
Disulfide bond3642 ↔ 3672 By similarity
Disulfide bond3646 ↔ 3677 By similarity
Disulfide bond3657 ↔ 3662 By similarity
Disulfide bond3818 ↔ 3856 By similarity
Disulfide bond3822 ↔ 3861 By similarity
Disulfide bond3834 ↔ 3846 By similarity
Disulfide bond3943 ↔ 3979 By similarity
Disulfide bond3954 ↔ 3958 By similarity
Disulfide bond3992 ↔ 3997 By similarity
Disulfide bond4012 ↔ 4049 By similarity
Disulfide bond4016 ↔ 4054 By similarity
Disulfide bond4027 ↔ 4039 By similarity
Disulfide bond4156 ↔ 4192 By similarity
Disulfide bond4167 ↔ 4171 By similarity
Disulfide bond4202 ↔ 4207 By similarity
Disulfide bond4261 ↔ 4298 By similarity
Disulfide bond4265 ↔ 4303 By similarity
Disulfide bond4276 ↔ 4288 By similarity
Disulfide bond4365 ↔ 4402 By similarity
Disulfide bond4376 ↔ 4378 By similarity
Disulfide bond4412 ↔ 4417 By similarity
Disulfide bond4609 ↔ 4643 By similarity
Disulfide bond4620 ↔ 4624 By similarity
Disulfide bond4653 ↔ 4658 By similarity
Disulfide bond4771 ↔ 4806 By similarity
Disulfide bond4775 ↔ 4811 By similarity
Disulfide bond4786 ↔ 4795 By similarity
Disulfide bond5047 ↔ 5095 By similarity
Disulfide bond5061 ↔ 5112 By similarity
Disulfide bond5071 ↔ 5128 By similarity
Disulfide bond5075 ↔ 5130 By similarity
Disulfide bond? ↔ 5133 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q700K0 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 1772AE67F02CA5E3

FASTA5,141550,649
        10         20         30         40         50         60 
MLLPALLFGM LWAPANGHWC EQIETVHVEE EVTPRREDLV PCTSLYHYSR LGWKLDLSWG 

        70         80         90        100        110        120 
GHVGLTRPPA LGLCAIYKPP ETRPATWNRT VRACCPGWGG IHCTEALAEA SPKGHCFVTW 

       130        140        150        160        170        180 
HCQPLAGSAN SSAGSLEECC AQPWGHSWWN SSSQMCLSCS GQHRPGNASS EGLLQPLAGA 

       190        200        210        220        230        240 
VGQLWSQRQR PSATCATWSG FHYQTFDGQH YHFLGQCTYL LAGAMDSTWA VHLRPSVHCP 

       250        260        270        280        290        300 
QPRQCWLVQV IMGPEEVLIQ DGEVSVKGQP VPVGESQLLH GMSLQWQGDW LVLSGGLGVV 

       310        320        330        340        350        360 
VRLDRSSSII ISVDHEFWGR TQGLCGLYNG RPEDDFVEPG GGLAMLAATF GNSWRLPGYE 

       370        380        390        400        410        420 
PGCLDTVEVA RGCEGLLEGT LTGLEAGKLQ AQAQDLCHQL LEDPFSQCHG QVPPDEYHET 

       430        440        450        460        470        480 
CLFAYCVGAT AGSGPEEQVK AVCATFANYA QACARQHIYV HWRKPGFCER LCPGGQLYSD 

       490        500        510        520        530        540 
CISSCPPSCS AVAQGEEGSC GKECVSGCEC PTGLFWDGAL CVPAAHCPCY YRRQRYAPGD 

       550        560        570        580        590        600 
TVKQQCNPCV CQDGRWHCAQ APCPAECAVG GDGHYCTFDG RSFSFRGNPG CQYSLVQDSV 

       610        620        630        640        650        660 
KGQLLVVLEH GACETGSCLH ALSAFLGKTH IQLRYSGAVL VDGQDVDLPW IGAEGFNVSH 

       670        680        690        700        710        720 
ASSTFLLLRW PGAWVLWGVA DPAVYITLDP RHAYQVQGLC GTFTWKQQDD FLTPAGDIET 

       730        740        750        760        770        780 
SVTAFASKFQ VSGDGRCPLV DNTPLSSCST YSQRLAFAEA ACAALHGHAF QECHGLVERE 

       790        800        810        820        830        840 
PFRLRCLESM CSCAPGRDCL CSVLSAYAHH CAQEGVLLQW RNETLCSVPC PGGQVYQECA 

       850        860        870        880        890        900 
PACGHYCGEP EDCKELGSCV AGCNCPPGLL WDLEGQCVPP SMCPCQLGGH RYAFNTTTTL 

       910        920        930        940        950        960 
KDCSHCICQE RGLWNCIAHH CPRQWALCPQ ELIYAPGACL LTCDSLGANH SCLAGSTDGC 

       970        980        990       1000       1010       1020 
VCPSGTVLLD KHCVSPDLCP CRHNGQWYPP NATIQEDCNI CVCQNQRWHC TGQRCSGWCQ 

      1030       1040       1050       1060       1070       1080 
ASGAPHYVTF DGLVFTFPGA CEYLLVREAG GRFSVSIQNL PCGASGLTCT KALAVRLDST 

      1090       1100       1110       1120       1130       1140 
VVHMLRGQAV TVNGVSIKLP KVYTGPGLSL HHAGLFLLLT TRLGLTLLWD GGTRVLVQLS 

      1150       1160       1170       1180       1190       1200 
PHFHGRVTGL CGNFDGDVSN DLRSRQGVLE PTAELTAHSW RLNPLCPEPG DLPHPCSVNA 

      1210       1220       1230       1240       1250       1260 
HRVNWARAHC EVILQPIFAP CHTEVPPQQY YEWCVYDACG CDTGGDCECL CSAIATYADE 

      1270       1280       1290       1300       1310       1320 
CARHRHHVRW RSQELCPLQC EGGQVYEPCG STCPPTCHDH HPELRWHCQA ITCVEGCFCP 

      1330       1340       1350       1360       1370       1380 
EGTLLHGGTC VELTDCPCEW QGSFFPPGAV LQKDCGNCTC QESQWHCNPS GAPCEEMEPG 

      1390       1400       1410       1420       1430       1440 
CAEGEALCRE SGHCVPLEWL CDNQDDCGDG SDEEGCDTSV CGEGQMSCQS GRCLPLSLIC 

      1450       1460       1470       1480       1490       1500 
DGQDDCGDGT DEQGCLCPQG FLACADGRCL PPALLCDGHP DCLDAADEES CLGWVSCTSG 

      1510       1520       1530       1540       1550       1560 
EVSCVDGPCI RTIQLCDGVW DCPDGADEGP VHCSSPSLPT PPAGIGQNPS TSSPDTSPSP 

      1570       1580       1590       1600       1610       1620 
VGSASPASPC SLSEFQCNSG ECTPRGWRCD REEDCTDGSD ELDCGGPCKL YQMPCAHGPH 

      1630       1640       1650       1660       1670       1680 
CLSPGQLCDG VAQCPDGSDE DPDVCEERSA SGGPNGTAVP CPEFSCPNGT CIDFLLVCDG 

      1690       1700       1710       1720       1730       1740 
SPDCELADET EPSLDEQGCG TWGSWGPWEP CSQTCGPGIQ SRNRNCSISS LHVLQNCPGL 

      1750       1760       1770       1780       1790       1800 
QHQSQSCFTE ACPVDGEWSS WSLWSPCSEP CGGTMTRHRQ CRPPQNGGQD CALLPGSTHS 

      1810       1820       1830       1840       1850       1860 
THQTSPCPQE GCLNVTCFGE LVFRPCAPCP LTCDDISGEA VCSPDRPCSS PGCWCPEGKV 

      1870       1880       1890       1900       1910       1920 
LGTEGRCVRP RQCPCLVDGI RYWPGQRIKM DCQLCFCQDG QPHRCRPNPE CAVDCGWSSW 

      1930       1940       1950       1960       1970       1980 
SPWAECLGPC SSQSLQWSFR SPNNPRLSGH GRQCRGIHRK ARRCQTEPCE GCEQWGLTYH 

      1990       2000       2010       2020       2030       2040 
VGERWRGGPC TVCECLHRSI TRCSPYCPIG SCPQSWVLVE GMGESCCHCA LPGKNQTMIP 

      2050       2060       2070       2080       2090       2100 
VTTPAPVPTP SPQIGASLVT YVLPPMSDAC YSPLGLAGLP TWAPSQPLEH STRAAPVEAP 

      2110       2120       2130       2140       2150       2160 
TAGPGPREDA YAEWHTQPLY LQLDLLWPRN LTGIMVQRAG SSAAYISNLS LQFSSDGLQW 

      2170       2180       2190       2200       2210       2220 
HSVLNSLSST LPPPKPSPES SNHMVPEVWT FDQMVQARYI RVWPHGSHLR DNNQQDIFLW 

      2230       2240       2250       2260       2270       2280 
VELLGCKPVP PLAPLCPGTR HRCANGDCAL KGGPCDGAVD CEDGSDEEGC GPLRASTASR 

      2290       2300       2310       2320       2330       2340 
VHSTARTPAL SPTQPGKFPF HPREGLADME HQQPKQESPM PSAGVSPSAS EGLLPVSGQS 

      2350       2360       2370       2380       2390       2400 
MQTLTTTSTF PPGLKSLHPG MAAVTVHSPH SVMPGTPVGQ SVSPRPFPLM RCGPGQVPCD 

      2410       2420       2430       2440       2450       2460 
VLGCVEQEQL CDGREDCLDG SDEQHCASPE PFTVPTTALP GLPASRALCS PSQLSCGSGE 

      2470       2480       2490       2500       2510       2520 
CLPLEHRCDL QVNCQDGSDE DDCVDCVLAP WSGWSDCSRS CGLGLIFQHR ELLRPPLPGG 

      2530       2540       2550       2560       2570       2580 
SCLLDQLRSQ PCFVQACPVA GAWAKWGPWE PCSVSCGGGH QSRQRSCVDP PPKNGGAPCP 

      2590       2600       2610       2620       2630       2640 
GPSHEKVLCN LQLCPGDTDC EPGRVHVNAE LCQKGLLPPC PPSCLDPEAN RSCSGHCVEG 

      2650       2660       2670       2680       2690       2700 
CRCPPGLFLQ DSHCLPLSEC PCLVGQKLMQ PGLAFLLDNC SQCICESGIL LCKPAACSQS 

      2710       2720       2730       2740       2750       2760 
CGWSAWSPWT ACDHSCGSGV RARFRSPTNP PAAFGGSPCE GDRQELQACY TDCGTDIPGW 

      2770       2780       2790       2800       2810       2820 
TPWTSWSSCS QSCLVPGGDP GRRQRSRLCP SSRDTFCPGE ATQEEPCSPS LCPVPSAWGL 

      2830       2840       2850       2860       2870       2880 
WASWSACSAS CNGGIQTRGR SCSGSAPGNP VCLGPHTQTR DCNVHPCTAQ CPGNMVFRSA 

      2890       2900       2910       2920       2930       2940 
EKCLEEGGPC PQLCLAQDPG VECTGSCAPG CSCPPGLFLH NASCLPRSQC PCQLHGQLYA 

      2950       2960       2970       2980       2990       3000 
PGAVARLDCN NCTCSSGEMV CTSERCPVAC GWSPWTPWSP CSQSCNVGIR RRFRAGTAPP 

      3010       3020       3030       3040       3050       3060 
AAFGGAECRG PNLDAEFCTL RPCQGPGAAW SSWTPCSVPC GGGYRNRTQG SGRHSPVEFS 

      3070       3080       3090       3100       3110       3120 
TCSLQPCAGP VPGVCPKDQQ WLDCAQGPAS CAHLSTPREA NQTCHPGCYC LSGMLLLNNV 

      3130       3140       3150       3160       3170       3180 
CVPAQDCPCA HRGRLHSPGS AVILPCENCS CVSGLITNCS SWPCEEGQPA WSSWTPWSVC 

      3190       3200       3210       3220       3230       3240 
SASCSPARRH RRRFCVRPST TAPFSLDLPT TVAAPTMLCP GPEAEEEPCL LPGCNQAGVW 

      3250       3260       3270       3280       3290       3300 
GPWSPWSGCS RSCGGGLRSR TRACDKPPPQ GLGDFCEGPQ AQGEACQAQP CPVANCSTIE 

      3310       3320       3330       3340       3350       3360 
GAEYSPCGPP CPRSCDDLVH CMWHCQPGCY CPPGKVLSAD GAICVQPHHC SCLDLLTGKR 

      3370       3380       3390       3400       3410       3420 
HHPGSQLMRP DGCNHCTCME GRLNCTDLPC QVSGDWCPWS EWTACSQPCR GQTRTRSRAC 

      3430       3440       3450       3460       3470       3480 
VCPAPQHGGA PCPEEAGETG VQHQMEACPN PTACPVDGAW SPWGSWSPCD ACLGQSYRSR 

      3490       3500       3510       3520       3530       3540 
MCSHPPPSDG GTPCLGGHQQ SRPCRNSSTP CTDCGGGQDL LPCGQPCPHS CQDLSLGSTC 

      3550       3560       3570       3580       3590       3600 
QPGSSGCQSG CGCPPGQLSQ DGLCVFPADC HCHFQPKAMG IPENQSRSVG SALSSWESLE 

      3610       3620       3630       3640       3650       3660 
PGEVVTGPCD NCTCVAGVLQ CHEVPSCPGP GIWSSWGPWE KCSVPCGGGE QLRSRQCARP 

      3670       3680       3690       3700       3710       3720 
PCPGLAQQSR TCHIHVCRET GCPAGRLYRE CQPSEGCPFS CAHVTGQVAC FSESCEEGCH 

      3730       3740       3750       3760       3770       3780 
CPEGTFQHHS ACVQECPCVL TVSLLQELGV ASTALRSYPV LLGDEGQPLG PGDELDPGQM 

      3790       3800       3810       3820       3830       3840 
LQTVCGNCSC VHGKLSCSME ECSRVRGYFG PWGMWSLCSH SCGGLGTRTR TRQCVLPTLA 

      3850       3860       3870       3880       3890       3900 
PAGLSCRGPL QDLEYCFSPE CPGTAGSTVE PVTGLAGGWG PWSPWSPCSH SCTDLTHPAW 

      3910       3920       3930       3940       3950       3960 
RSRTRLCLAN CTVGDSSQER PCNLPSCTTL PLCPGPGCGS ENCFWTSWAP WEPCSRSCGV 

      3970       3980       3990       4000       4010       4020 
GQQRRLRAYH PPGPGGHWCP DILTAYQERR FCNLRACPVP GGWSHWSPWS WCDRSCGGGR 

      4030       4040       4050       4060       4070       4080 
SLRSRSCSSP PPKNGGASCV GERHHVRSCN PMPCEKDCPA GMEMVSCANR CPYSCSDLQE 

      4090       4100       4110       4120       4130       4140 
AVMCQEDQAC QLGCRCSEGF LEQDGGCVPV GHCECTDAQG RSWAPGSQHQ DACNNCSCQA 

      4150       4160       4170       4180       4190       4200 
GQLSCTAQPC PPPAHCAWSH WSAWSACSHS CGPHGQQSRF RSSTSGSWAL ECQKEQSQSQ 

      4210       4220       4230       4240       4250       4260 
PCPEDPCPPL CLHEAHLHVL GDNWLHGECQ QCSCTPEGVI CKDTDCAVPG GWTLWSSWSY 

      4270       4280       4290       4300       4310       4320 
CSVSCGGGSQ VRTRSCMVSA PQHGSPSCQG PDTQTQHCGQ QLCLQLLEIC SWGPWGPCSR 

      4330       4340       4350       4360       4370       4380 
SCGTGLASRS GSCPCLLTKE DSECNDTFSG LDTQACYPGP CQEDCMWSDW SSWTRCSCKI 

      4390       4400       4410       4420       4430       4440 
LVQQRYRHQV PAPGQAGEGT LCTGLDGHFR PCAIGNCSED SCLPPFEFQS CGSPCAGLCA 

      4450       4460       4470       4480       4490       4500 
THLSHQLCQD LPPCQPGCYC PMGLLEQDGG CILPEQCNCW HTSGEGARVT LAPGHRLQLG 

      4510       4520       4530       4540       4550       4560 
CKECVCQSGE LQCSSQGCEG LLPLTGWSEW SPCGPCLPQS ALAPDSRTAL EVHWPLNTSV 

      4570       4580       4590       4600       4610       4620 
TLLASEQYRH RLCLDPETGR PWAGDPALCT VPLSQQRLCS DPGACHDTCQ WGPWGPWSPC 

      4630       4640       4650       4660       4670       4680 
QVPCSGGFKL RWREASDNSV GECRGPWAQT ESCNMGSCPG ESCETRDTVF TLDCANQCPR 

      4690       4700       4710       4720       4730       4740 
SCADLWEGVQ CLQGPCSPGC RCPPGQLVQD GHCVPISSCR CGLPSANASW ELAPTQVVQL 

      4750       4760       4770       4780       4790       4800 
DCHNCTCING TLMCPYPECP VLGPWSPWSE CSAVCGGGTM VRYRSCEEHP DSAPCQALDM 

      4810       4820       4830       4840       4850       4860 
EQRVECNLQT CPECPPGQVL STCATLCPSF CSHLWPGTIC VREPCQLGCG CPGGQLLHSG 

      4870       4880       4890       4900       4910       4920 
TCIPPEACPC TRLSLPWGLT LPLEEQAQEL PSGTVLTWNC THCTCQGGVF TCSHTDCQEC 

      4930       4940       4950       4960       4970       4980 
PPGEILQLGE LRPCEKTCLE MNKTQAWSNC TEAQVPGCVC QLGHFRSHTG LCVPEDHCEC 

      4990       5000       5010       5020       5030       5040 
WHHGSPHLPG SEWQEACESC RCLHGKSVCT QHCPELSCAQ GEVVVQEPGS CCPICQQDTL 

      5050       5060       5070       5080       5090       5100 
EEEPVSCRHL TELRNLTKGP CHLDQVEVSY CSGHCRSSTN VMTEEPYLQS QCDCCSYRLD 

      5110       5120       5130       5140 
PDSPVRILNL LCPDGRTEPV LLPVIHNCHC SACQGGEFSK H 

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References

[1]"Conservation of mammalian SCO-spondin."
Meiniel O.
Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ629845 mRNA. Translation: CAF33425.1.
RefSeqNP_001007017.1. NM_001007016.1.
UniGeneRn.124116.

3D structure databases

ProteinModelPortalQ700K0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ700K0. 1 interaction.
STRING10116.ENSRNOP00000037189.

Proteomic databases

PaxDbQ700K0.
PRIDEQ700K0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000035906; ENSRNOP00000037189; ENSRNOG00000025848.
GeneID474348.
KEGGrno:474348.
UCSCRGD:1549716. rat.

Organism-specific databases

CTD23145.
RGD1549716. Sspo.

Phylogenomic databases

eggNOGNOG12793.
GeneTreeENSGT00730000110607.
HOGENOMHOG000154433.
HOVERGENHBG080794.
InParanoidQ700K0.
OMACLDPEAN.
OrthoDBEOG73V6J9.
PhylomeDBQ700K0.
TreeFamTF344272.

Gene expression databases

GenevestigatorQ700K0.

Family and domain databases

Gene3D2.60.120.260. 1 hit.
4.10.400.10. 10 hits.
InterProIPR000421. Coagulation_fac_5/8-C_type_dom.
IPR006207. Cys_knot_C.
IPR008979. Galactose-bd-like.
IPR023415. LDLR_class-A_CS.
IPR002172. LDrepeatLR_classA_rpt.
IPR028504. SCO-spondin.
IPR000884. Thrombospondin_1_rpt.
IPR002919. TIL_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR006552. VWC_out.
IPR001007. VWF_C.
IPR001846. VWF_type-D.
[Graphical view]
PANTHERPTHR22905. PTHR22905. 1 hit.
PfamPF08742. C8. 3 hits.
PF00754. F5_F8_type_C. 1 hit.
PF00057. Ldl_recept_a. 8 hits.
PF01826. TIL. 14 hits.
PF00090. TSP_1. 22 hits.
PF00093. VWC. 1 hit.
PF00094. VWD. 3 hits.
[Graphical view]
PRINTSPR00261. LDLRECEPTOR.
SMARTSM00832. C8. 3 hits.
SM00192. LDLa. 10 hits.
SM00209. TSP1. 25 hits.
SM00214. VWC. 4 hits.
SM00215. VWC_out. 1 hit.
SM00216. VWD. 3 hits.
[Graphical view]
SUPFAMSSF49785. SSF49785. 1 hit.
SSF57424. SSF57424. 10 hits.
SSF57567. SSF57567. 15 hits.
SSF82895. SSF82895. 25 hits.
PROSITEPS01225. CTCK_2. 1 hit.
PS01186. EGF_2. 2 hits.
PS50022. FA58C_3. 1 hit.
PS01209. LDLRA_1. 8 hits.
PS50068. LDLRA_2. 10 hits.
PS50092. TSP1. 24 hits.
PS01208. VWFC_1. 1 hit.
PS50184. VWFC_2. 2 hits.
PS51233. VWFD. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio697202.
PROQ700K0.

Entry information

Entry nameSSPO_RAT
AccessionPrimary (citable) accession number: Q700K0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families