Glycerol-3-phosphate dehydrogenase [NAD+] 1 - Pichia jadinii (Yeast)

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Reviewed, UniProtKB/Swiss-Prot Q6ZZF4 (GPD1_PICJA)

Last modified November 25, 2008. Version 27. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein names

Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD+] 1
EC=1.1.1.8

Gene names

Name:

gpd1

Organism

Pichia jadinii (Yeast) (Candida utilis)

Taxonomic identifier

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Pichia

Protein attributes

Sequence length	393 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH.
Sequence similarities	Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro glycerol-3-phosphate catabolic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	glycerol-3-phosphate dehydrogenase complex Inferred from electronic annotation. Source: InterPro
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro glycerol-3-phosphate dehydrogenase (NAD+) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

393

Glycerol-3-phosphate dehydrogenase [NAD+] 1

PRO_0000138093

Regions

Nucleotide binding

6

NAD By similarity

Region

2

Substrate binding By similarity

Sites

Active site

1

Proton acceptor By similarity

Binding site

1

NAD By similarity

Binding site

1

NAD; via amide nitrogen By similarity

Binding site

1

Substrate By similarity

Binding site

1

NAD; via amide nitrogen By similarity

Binding site

1

NAD By similarity

Binding site

1

NAD By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

Q6ZZF4-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: A87107CBB8B605D9
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393

42,957

        10         20         30         40         50         60 
MLRIGKLNLS TMSSAQQRLA QVGSHLTAQK QSLAPQRPYK ITVIGSGNWG TTIAKVLAEN 

        70         80         90        100        110        120 
AGLRPHLFQH QVDMWVFEEK INGVNLTEII NTQHENVKYL PGIKLPKNLH AEPSIVKAAE 

       130        140        150        160        170        180 
GADLLVFNIP HQFLPGICKQ LSKATLKPHV RAISCLKGLE VTPNGCKLLS TYITEHLGVH 

       190        200        210        220        230        240 
CGALSGANLA PEVAKEKWSE TTVAYRLPND FQGHGKDIDR YVLRAAFHRP YFHVRVIEDV 

       250        260        270        280        290        300 
AGVSLAGALK NVVALGVGFV HGLNWGDNAA SAIQRFGLNE TIKFAEVFFP GETNQDTFTK 

       310        320        330        340        350        360 
ESAGVADLIT TCSGGRNVRV AKAMAITGKS AVEVERELLN GQSAQGIITS KEVHELLAAK 

       370        380        390 
NLTKEFPLFE AIYQIVYGTE SIERLPELIE EDE

References

[1]

"Identification of the genes GPD1 and GPD2 of Pichia jadinii."
Ostermann K., Richter M., Zscharnack M., Rothe R., Walther T., Roedel G.
DNA Seq. 17:452-457(2006) [PubMed: 17381046] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 9950 / CBS 5609 / DSM 2361 / IFO 0998 / NRRL Y-900.

Cross-references

Sequence databases
	AJ632339 Genomic DNA. Translation: CAG15347.1. AJ632341 Genomic DNA. Translation: CAG15350.1.
3D structure databases
HSSP	HSSP built from PDB template 1JDJ based on UniProtKB P90551.
ModBase	Search...
Family and domain databases
InterPro	IPR013328. DHase_multihelical. IPR016040. NAD(P)-bd. IPR017751. NAD-dep_Gly3P_DH_euk. IPR006168. NAD-dep_Gly3P_DHase. IPR011128. NAD-dep_Gly3P_DHase_N. IPR006109. NAD_Gly3P_DHase_C. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
PANTHER	PTHR11728. NAD_Gly3P_DH. 1 hit.
Pfam	PF07479. NAD_Gly3P_dh_C. 1 hit. PF01210. NAD_Gly3P_dh_N. 1 hit. [Graphical view]
PIRSF	PIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTS	PR00077. GPDHDRGNASE.
ProDom	PD001278. NAD_Gly3P_C. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00957. NAD_G3PDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GPD1_PICJA

Accession

Primary (citable) accession number: Q6ZZF4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	July 5, 2004
Last modified:	November 25, 2008
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents