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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)] 2

Gene

gpd2

Organism
Cyberlindnera jadinii (Torula yeast) (Pichia jadinii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei152NAD; via amide nitrogenBy similarity1
Binding sitei152SubstrateBy similarity1
Binding sitei185NAD; via amide nitrogenBy similarity1
Active sitei243Proton acceptorBy similarity1
Binding sitei308NADBy similarity1
Binding sitei337NADBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi41 – 46NADBy similarity6

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)] 2 (EC:1.1.1.8)
Gene namesi
Name:gpd2
OrganismiCyberlindnera jadinii (Torula yeast) (Pichia jadinii)
Taxonomic identifieri4903 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeCyberlindnera

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001380941 – 394Glycerol-3-phosphate dehydrogenase [NAD(+)] 2Add BLAST394

Proteomic databases

PRIDEiQ6ZYA7.

Structurei

3D structure databases

ProteinModelPortaliQ6ZYA7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni308 – 309Substrate bindingBy similarity2

Sequence similaritiesi

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZYA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDIGESESD ISTDVSALPM LSHSVSYTSI QKPPFVVSVI GSGNWGTTVA
60 70 80 90 100
KIIAENTREN PLLFEQKVRM WVYEEEFEGS NLSDIINTEH VNKKYLPGIK
110 120 130 140 150
LPDNLVAVPD LLEAVQYSNI LIFNIPHQHL EKILSQLRGN IDPRARAISC
160 170 180 190 200
LKGLRVNLDG VELLPDIIQD ALGIHCGVLA GANLAQEVAE QRFSETTVGY
210 220 230 240 250
PLPADYKPGD VDHTVLYTLF HRPYFHVHVI EDIAGISCAG ALKNIIAISV
260 270 280 290 300
GFVEGLEWGD NAKAAMLRRG LLEMIKFGRK FFPGCLVSSF TEESAGVADL
310 320 330 340 350
FTTCTGGRNF KLAKIMAQTG KSAHEVEKEI LNGQSAQGLI TAKEIHELIK
360 370 380 390
NKGCEEEFPL FETTYQILFH GVRIGILPYM LENKWSISKP NYSS
Length:394
Mass (Da):43,530
Last modified:March 29, 2005 - v2
Checksum:i5970F34B5D528C15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ635370 Genomic DNA. Translation: CAG25779.2.
AJ632340 Genomic DNA. Translation: CAG15348.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ635370 Genomic DNA. Translation: CAG25779.2.
AJ632340 Genomic DNA. Translation: CAG15348.2.

3D structure databases

ProteinModelPortaliQ6ZYA7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ6ZYA7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGPD2_CYBJA
AccessioniPrimary (citable) accession number: Q6ZYA7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: March 29, 2005
Last modified: October 5, 2016
This is version 59 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.