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Q6ZYA7 (GPD2_CYBJA) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)] 2

EC=1.1.1.8
Gene names
Name:gpd2
OrganismCyberlindnera jadinii (Torula yeast) (Pichia jadinii)
Taxonomic identifier4903 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeCyberlindnera

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 394394Glycerol-3-phosphate dehydrogenase [NAD(+)] 2
PRO_0000138094

Regions

Nucleotide binding41 – 466NAD By similarity
Region308 – 3092Substrate binding By similarity

Sites

Active site2431Proton acceptor By similarity
Binding site1521NAD; via amide nitrogen By similarity
Binding site1521Substrate By similarity
Binding site1851NAD; via amide nitrogen By similarity
Binding site3081NAD By similarity
Binding site3371NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6ZYA7 [UniParc].

Last modified March 29, 2005. Version 2.
Checksum: 5970F34B5D528C15

FASTA39443,530
        10         20         30         40         50         60 
MTDIGESESD ISTDVSALPM LSHSVSYTSI QKPPFVVSVI GSGNWGTTVA KIIAENTREN 

        70         80         90        100        110        120 
PLLFEQKVRM WVYEEEFEGS NLSDIINTEH VNKKYLPGIK LPDNLVAVPD LLEAVQYSNI 

       130        140        150        160        170        180 
LIFNIPHQHL EKILSQLRGN IDPRARAISC LKGLRVNLDG VELLPDIIQD ALGIHCGVLA 

       190        200        210        220        230        240 
GANLAQEVAE QRFSETTVGY PLPADYKPGD VDHTVLYTLF HRPYFHVHVI EDIAGISCAG 

       250        260        270        280        290        300 
ALKNIIAISV GFVEGLEWGD NAKAAMLRRG LLEMIKFGRK FFPGCLVSSF TEESAGVADL 

       310        320        330        340        350        360 
FTTCTGGRNF KLAKIMAQTG KSAHEVEKEI LNGQSAQGLI TAKEIHELIK NKGCEEEFPL 

       370        380        390 
FETTYQILFH GVRIGILPYM LENKWSISKP NYSS 

« Hide

References

[1]"Identification of the genes GPD1 and GPD2 of Pichia jadinii."
Ostermann K., Richter M., Zscharnack M., Rothe R., Walther T., Roedel G.
DNA Seq. 17:452-457(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 9950 / CBS 5609 / DSM 2361 / NBRC 0998 / NRRL Y-900.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ635370 Genomic DNA. Translation: CAG25779.2.
AJ632340 Genomic DNA. Translation: CAG15348.2.

3D structure databases

ProteinModelPortalQ6ZYA7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. SSF48179. 1 hit.
TIGRFAMsTIGR03376. glycerol3P_DH. 1 hit.
PROSITEPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGPD2_CYBJA
AccessionPrimary (citable) accession number: Q6ZYA7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: March 29, 2005
Last modified: October 16, 2013
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families