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Q6ZYA7

- GPD2_CYBJA

UniProt

Q6ZYA7 - GPD2_CYBJA

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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)] 2

Gene

gpd2

Organism
Cyberlindnera jadinii (Torula yeast) (Pichia jadinii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei152 – 1521NAD; via amide nitrogenBy similarity
Binding sitei152 – 1521SubstrateBy similarity
Binding sitei185 – 1851NAD; via amide nitrogenBy similarity
Active sitei243 – 2431Proton acceptorBy similarity
Binding sitei308 – 3081NADBy similarity
Binding sitei337 – 3371NADBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi41 – 466NADBy similarity

GO - Molecular functioni

  1. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: UniProtKB-EC
  2. NAD binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. glycerol-3-phosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)] 2 (EC:1.1.1.8)
Gene namesi
Name:gpd2
OrganismiCyberlindnera jadinii (Torula yeast) (Pichia jadinii)
Taxonomic identifieri4903 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeCyberlindnera

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 394394Glycerol-3-phosphate dehydrogenase [NAD(+)] 2PRO_0000138094Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ6ZYA7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni308 – 3092Substrate bindingBy similarity

Sequence similaritiesi

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZYA7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTDIGESESD ISTDVSALPM LSHSVSYTSI QKPPFVVSVI GSGNWGTTVA
60 70 80 90 100
KIIAENTREN PLLFEQKVRM WVYEEEFEGS NLSDIINTEH VNKKYLPGIK
110 120 130 140 150
LPDNLVAVPD LLEAVQYSNI LIFNIPHQHL EKILSQLRGN IDPRARAISC
160 170 180 190 200
LKGLRVNLDG VELLPDIIQD ALGIHCGVLA GANLAQEVAE QRFSETTVGY
210 220 230 240 250
PLPADYKPGD VDHTVLYTLF HRPYFHVHVI EDIAGISCAG ALKNIIAISV
260 270 280 290 300
GFVEGLEWGD NAKAAMLRRG LLEMIKFGRK FFPGCLVSSF TEESAGVADL
310 320 330 340 350
FTTCTGGRNF KLAKIMAQTG KSAHEVEKEI LNGQSAQGLI TAKEIHELIK
360 370 380 390
NKGCEEEFPL FETTYQILFH GVRIGILPYM LENKWSISKP NYSS
Length:394
Mass (Da):43,530
Last modified:March 29, 2005 - v2
Checksum:i5970F34B5D528C15
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ635370 Genomic DNA. Translation: CAG25779.2.
AJ632340 Genomic DNA. Translation: CAG15348.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ635370 Genomic DNA. Translation: CAG25779.2 .
AJ632340 Genomic DNA. Translation: CAG15348.2 .

3D structure databases

ProteinModelPortali Q6ZYA7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProi IPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PANTHERi PTHR11728. PTHR11728. 1 hit.
Pfami PF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSi PR00077. GPDHDRGNASE.
SUPFAMi SSF48179. SSF48179. 1 hit.
TIGRFAMsi TIGR03376. glycerol3P_DH. 1 hit.
PROSITEi PS00957. NAD_G3PDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification of the genes GPD1 and GPD2 of Pichia jadinii."
    Ostermann K., Richter M., Zscharnack M., Rothe R., Walther T., Roedel G.
    DNA Seq. 17:452-457(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 9950 / CBS 5609 / DSM 2361 / NBRC 0998 / NRRL Y-900.

Entry informationi

Entry nameiGPD2_CYBJA
AccessioniPrimary (citable) accession number: Q6ZYA7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: March 29, 2005
Last modified: October 1, 2014
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3